A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Dmel\412{}bw1 Insertion

General Information
Symbol Dmel\412{}bw1 Species D. melanogaster
Name FlyBase ID FBti0014269
Feature type transposable_element Created / Updated 2006-08-22/2006-08-22
Description
Inserted element 412 Localized function
Affected gene(s) bw Expression data
Causes allele(s) bw1 Viability / fertility
LINE ID Stock availability
Genomic Location
Chromosomal location 2R ( 59E2-59E3 ) Sequence location
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Chromosome (arm)
Sequence Location
Orientation
Cytological location
(computed by FlyBase)
59E2-59E3 ( near gene of known cytology )
Cytological location
(reported)
59E2-59E3 (reported as inferred from sequence location)
(Quesneville et al., 2005.6.22)
59E2-59E3 (reported as inferred from sequence location)
(Kaminker et al., 2002)
Chromosome in situ
hide Sequence Data
Flanking sequence
hide Inserted Element
Construct 412
Location-dependent
role 		 
Size
Associated alleles
Molecular map
Transposon class
Element type
hide Affected Gene(s)
Insertion within gene
Insertion may
affect gene
bw
(Dreesen et al., 1988)
Orientation
(relative to gene)
Gene
Orientation
References
 
 
 
hide Alleles and Phenotypes
Causes alleles
bw1
(Dreesen et al., 1988, FlyBase Genome Annotators, 2002-2003)
Lethality
References
Sterility
References
hide Phenotype Manifest In
pigment cell
 
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Statement
Reference
Eye colour: off-white, with In(2LR)Nella.
(Henikoff et al., 1995)
The increased resistance of bw1 homozygous males to enflurane is not enhanced or suppressed by st1/st1. bw1/+, st1/+ males from bw1, st1 homozygous mothers show increased resistance to halothane when tested under red light and a slight increase in this resistance when tested under white light. A maternal effect is necessary for this phenotype as it is not seen in bw1/+, st1/+ males from bw1, st1 homozygous fathers.
(Campbell and Nash, 2001)
Eye colour: brown. Eye colour: light brownish wine on emergence, darkening to garnet. Eye colour: white, with cn1. Eye colour: white, with st1. Eye colour: white, with v1.
 
Malpighian tubule colour: pale yellow. Testes colour: colourless.
(Beadle, 1937)
Red pigments lacking. Xanthommatin mostly replaced by dihydroxanthommatin. Pigment granules present but somewhat smaller than in wild type.
(Phillips et al., 1973)
Affects the formation of drosopterins and reduces level of ommochrome in the eye.
(Tearle, 1991)
Male heterozygous and homozygous bw1 flies have an increased resistance to the anesthetic enflurane compared to wild-type controls, as judged by climbing ability. This effect is true whether enflurane resistance is measured in regular light or red light. bw1 male flies show no increased resistance to the anesthetic halothane compared to wild-type flies when climbing ability is measured in regular light. However, bw1 mutants show increased sensitivity to this anesthetic when climbing ability is measured in red light.
(Campbell and Nash, 2001)
hide Expression Data
Reporter Expression
Stage
Tissue/Position
Reference
Additional Information
Statement
Reference
Assay mode
Marker for
Reflects
expression of
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FlyView (LinkOut)
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Line ID
Origin as a multiple insertion line
hide Progenitor(s) within the Genome
hide Related Aberration or Balancer
Aberration
Balancer
hide Stocks ( 0 )
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hide Synonyms & Secondary IDs
Reported As
Symbol Synonym
412{}878
(FlyBase Genome Annotators, 2002-2003, Kaminker et al., 2002, FlyBase, 1992-)
412{}bw1
(FlyBase, 1992-)
?{}bw1
(Dreesen et al., 1988, FlyBase, 1992-)
TE18870
(FlyBase Genome Annotators, 2002-2003, FlyBase, 1992-)
Secondary FlyBase IDs
  • FBti0018870
hide References ( 11 )
Research paper
Quesneville et al., 2005, PLoS Comput. Biol. 1(2): 166--175
Combined evidence annotation of transposable elements in genome sequences. [FBrf0186342]
Kaminker et al., 2002, GenomeBiol. 3(12): RESEARCH0084.11--0084.20
The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective. [FBrf0155828]
Campbell and Nash, 2001, J. Neurobiol. 49(4): 339--349
Volatile general anesthetics reveal a neurobiological role for the white and brown genes of Drosophila melanogaster. [FBrf0141614]
Henikoff et al., 1995, Genetics 140(3): 1007--1017
Distance and pairing effects on the brown<up>Dominant</up> heterochromatic element in Drosophila. [FBrf0083184]
Tearle, 1991, Genet. Res. 57: 257--266
Tissue specific effects of ommochrome pathway mutations in Drosophila melanogaster. [FBrf0054090]
Dreesen et al., 1988, Molec. Cell. Biol. 8: 5206--5215
The brown protein of Drosophila melanogaster is similar to the white protein and to components of active transport complexes. [FBrf0048677]
Phillips et al., 1973, Genetics 73(1): 45--56
Terminal synthesis of xanthommatin in Drosophila melanogaster. [FBrf0025065]
Beadle, 1937, Genetics 22: 587--611
Development of eye colors in Drosophila: fat bodies and Malpighian tubes as sources of diffusible substances. [FBrf0003911]
Personal communication to FlyBase
Quesneville et al., 2005.6.22, r4 TE data.
r4 TE data. [FBrf0184336]
FlyBase analysis
FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome.
Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886]
FlyBase, 1992-, FlyBase curation
FlyBase curation. [FBrf0105495]