Dhet\Uhu

General Information
Symbol	Dhet\Uhu	Species	D.heteroneura
Name	Uhu element	FlyBase ID	FBte0000190
Feature type	natural transposable element	Created / Updated	2006-12-04/2006-12-04
Sequences & Components
Complete element (bp)
Terminal repeat (bp)
Reference sequence	transposon_sequence_set.embl.txt.gz
Component genes	Dhet\Uhu\T
Sequence Accessions
	DDBJ/EMBL/GenBank X63029 X63028 X17356
Sequence Ontology (SO)
Transposon type	transposable_element
Insertions & Copy Number
Copy number and comments
Search for	All insertions of this transposon Insertions in the sequenced genome Insertions in other genomes
Target Site Duplication
Size (bp)
Orthologs
Curated drosophilid orthologs	Dpin\Uhu (Biemont and Cizeron, 1999) Dmel\Uhu Dsil\Uhu Dset\Uhu Dpla\Uhu Dpic\Uhu Dpec\Uhu Dorn\Uhu Dnig\Uhu Dmic\Uhu Dgri\Uhu Ddif\Uhu Dadu\Uhu Dadi\Uhu
Comments
	Distribution of the Uhu element is studied in several species of the Hawaiian Drosophila. An inverse correlation between the copy number and the age of the island on which the species is epidemic exists suggesting a relationship between speciation and the activity of the transposable element. (Wisotzkey et al., 1997) DNA sequence of three Dhet\Uhu isolates has been determined, and compared to sequences from four other Hawaiian species, D.silvestris, D.differens, D.planitibia and D.picticornis, and D.melanogaster. The element arose at least 5Myr ago, at the time of divergence of D.picticornis from the other species examined. Uhu elements may have been transmitted vertically and that transposition may have been activated at the time of the formation of each species as it colonized the newly formed islands of the Hawaiian archipelago. (Brezinsky et al., 1992) A Dhet\Uhu element has been cloned and sequenced. Dhet\Uhu is a transposable element approximately 1650bp long, with 46-50bp inverse imperfect repeats, and contains a large open reading frame potentially encoding a 192 amino acid protein. (Brezinsky et al., 1990)
Other Information
Etymology

External Crossreferences
Sequence Crossreferences
	DDBJ/EMBL/GenBank X63029 X63028 X17356
Other Crossreferences

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Dhet\Uhu uhu (Biemont and Cizeron, 1999)
Name Synonym	Uhu element
Secondary FlyBase IDs
	FBgn0003948
References ( 8 )
Research paper	Biemont and Cizeron, 1999, Genetica 105(1): 43--62 Distribution of transposable elements in Drosophila species. [FBrf0111330] Wisotzkey et al., 1997, Chromosoma 106(7): 465--477 Biogeographic analysis of the UHU and LOA elements in the Hawaiian Drosophila. [FBrf0099782] Felger and Hunt, 1993, Methods Enzymol. 224: 322--334 Detection and characterization of transposable elements. [FBrf0068485] Brezinsky et al., 1992, Genetica 86: 21--35 Evolution of the transposable element Uhu in five species of Hawaiian Drosophila. [FBrf0056184] Kidwell, 1992, Genetica 86: 275--286 Horizontal transfer of P-elements and other short inverted repeat transposons. [FBrf0056188] Brezinsky et al., 1990, Nucleic Acids Res. 18: 2053--2059 The transposable element Uhu from Hawaiian Drosophila - member of the widely dispersed class of Tc1-like transposons. [FBrf0052715]
Review	Robertson, 1995, J. Insect Physiol. 41(2): 99--105 The Tc1-mariner superfamily of transposons in animals. [FBrf0080353]
Abstract	Wisotzkey and Hunt, 1994, A. Dros. Res. Conf. 35 Suppl.: 366A An ancient origin of the transposable element Uhu in the Hawaiian Drosophila. [FBrf0067655]