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Reference
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| Citation |
Nguyen, D.N., Liu, Y., Litsky, M.L., Reinke, R. (1997). The sidekick gene, a member of the immunoglobulin superfamily, is required for pattern formation in the Drosophila eye. Development 124(17): 3303--3312. |
| FlyBase ID |
FBrf0098319 |
| Type of publication |
Research paper |
| Offprint Available |
Yes |
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External Crossreferences
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| PubMed ID |
9310325 |
| PubMed Abstract |
In the Drosophila eye imaginal disc the photoreceptor cells (R cells) differentiate according to a precise spatial and temporal
order. The sidekick (sdk) gene is necessary to prevent extra R cells from differentiating during eye disc development. The
extra cell appears between R3 and R4 early in R cell clusters and is most likely the result of the mystery cell inappropriately
differentiating as an R cell. Mosaic analysis shows that sdk is required neither in the R cells nor in the extra cell, suggesting
that sdk is necessary in the surrounding undifferentiated cells. The sdk gene codes for a protein that is a member of the
immunoglobulin superfamily, having six immunoglobulin domains, thirteen fibronectin repeats and a transmembrane domain. The
protein structure is consistent with its participation in cell-cell interaction during eye development.
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| Biosis |
99783778 |
| Zoological record |
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Associated Information
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| Comments |
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| Text of personal communication |
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| Associated files |
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Related Publications
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Also Published As
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Other Reference Information
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| Secondary IDs |
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| Language of publication |
English |
| Additional language(s) of abstract |
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| ISBN |
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| Place of publication |
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Published In
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| Abbreviation |
Development |
| Title |
Development |
| Authors |
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| Volume range |
99- |
| Year range |
1987- |
| Page range |
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| Publisher |
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| Place of publication |
Cambridge |
| Language of publication |
English |
| ISBN/ISSN |
0950-1991 |
| CODEN |
DEVPED |
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Data from Reference
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| Aberrations (9)
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| Alleles (7)
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| Genes (11)
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| Insertions (3)
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