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| Citation | Dimitratos, S.D., Woods, D.F., Bryant, P.J. (1997). Camguk, lin-2, and CASK: novel membrane-associated guanylate kinase homologs that also contain CaM kinase domains. Mech. Dev. 63(1): 127--130. |
| FlyBase ID | FBrf0093421 |
| Type of publication | Research paper |
| Offprint Available | Yes |
| External Crossreferences | |
| PubMed ID | 9178262 |
| PubMed Abstract | MAGUKs (membrane-associated guanylate kinase homologs) are proteins involved in cell junction organization, tumor suppression, and signalling. Their structure includes one or three copies of a DHR or PDZ domain (discs-large homologous region or PSD-95/SAP90, discs-large ZO-1 homologous domain), an SH3 domain, and a guanylate kinase domain. MAGUKs were classified into two subfamilies: Dlg-like with three DHR/PDZ domains and p55-like with a single DHR/PDZ domain. There is now a new subfamily whose members have a novel domain structure: a calcium/calmodulin-dependent protein kinase domain in the N-terminus as well as the DHR/PDZ, SH3 and GUK domains in the C-terminus. These new MAGUKs may regulate transmembrane molecules that bind calcium, calmodulin, or nucleotides, camguk (cmg) is a Drosophila member of this novel MAGUK subfamily; we report its sequence and domain structure. |
| Biosis | 99611951 |
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| Secondary IDs | |
| Language of publication | English |
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| Abbreviation | Mech. Dev. |
| Title | Mechanisms of Development |
| Authors | |
| Volume range | 33- |
| Year range | 1990- |
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| Publisher | |
| Place of publication | Shannon |
| Language of publication | English |
| ISBN/ISSN | 0925-4773 |
| CODEN | MEDVE6 |
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