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Reference
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| Citation |
Huber, A., Schulz, S., Bentrop, J., Groell, C., Wolfrum, U., Paulsen, R. (1997). Molecular cloning of Drosophila Rh6 rhodopsin: the visual pigment of a subset of R8 photoreceptor cells. FEBS Lett. 406(1-2): 6--10. |
| FlyBase ID |
FBrf0093128 |
| Type of publication |
Research paper |
| Offprint Available |
Yes |
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External Crossreferences
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| PubMed ID |
9109375 |
| PubMed Abstract |
By screening retinal cDNA libraries for photoreceptor-specifically expressed genes we have isolated and sequenced a cDNA clone
encoding the rhodopsin (Rh6) of a subset of R8 photoreceptor cells of the Drosophila compound eye. Compared to the other visual
pigments of Drosophila, this rhodopsin is equally homologous to Rh1 and Rh2 (51% amino acid identity) but shows only 32% and
33% amino acid identity with Rh3 and Rh4, respectively. The open reading frame codes for a protein of 369 amino acids (MW
= 41691). The primary structure of Rh6 displays sites typical for rhodopsin molecules in general, for example, a chromophore
binding site in transmembrane domain VII, sequence motifs in the intracellular loops 2 and 3 required for the binding of a
heterotrimeric G-protein, and a glycosylation site near the N-terminus which seems to be important for protein transport and
maturation. Since R8 cells are founder cells in the developing compound eye, the isolation of a rhodopsin gene expressed in
these cells may aid the understanding of terminal differentiation of photoreceptor cells.
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| Biosis |
99517842 |
| Zoological record |
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Associated Information
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| Text of personal communication |
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Also Published As
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Other Reference Information
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| Secondary IDs |
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| Language of publication |
English |
| Additional language(s) of abstract |
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| ISBN |
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Published In
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| Abbreviation |
FEBS Lett. |
| Title |
FEBS Letters (Federation of European Biochemical Societies) |
| Authors |
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| Volume range |
1- |
| Year range |
1968- |
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| Publisher |
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| Place of publication |
Amsterdam |
| Language of publication |
English |
| ISBN/ISSN |
0014-5793 |
| CODEN |
FEBLAL |
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Data from Reference
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| Alleles (3)
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| Genes (4)
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