Reference Report

Reference
Citation	Ronsseray, S., Lehmann, M., Nouaud, D., Anxolabehere, D. (1996). The regulatory properties of autonomous subtelomeric P elements are sensitive to a Suppressor of variegation in Drosophila melanogaster. Genetics 143(4): 1663--1674.
FlyBase ID	FBrf0089801
Type of publication	Research paper
Offprint Available	Yes
External Crossreferences
PubMed ID	8844154
PubMed Abstract	Genetic recombination was used in Drosophila melanogaster to isolate P elements, inserted at the telomeres of X chromosomes (cytological site IA) from natural populations, in a genetic background devoid of other P elements. We show that complete maternally inherited P repression in the germline (P cytotype) can be elicited by only two autonomous P elements at 1A and that a single element at this site has partial regulatory properties. The analysis of the surrounding chromosomal regions of the P elements at 1A shows that in all cases these elements are flanked by Telomeric Associated Sequences, tandemly repetitive noncoding sequences that have properties of heterochromatin. In addition, we show that the regulatory properties of P elements at 1A can be inhibited by some of the mutant alleles of the Su(var)205 gene and by a deficiency of this gene. However, the regulatory properties of reference P strains (Harwich and Texas 007) are not impaired by Su(var)205 mutations. Su(var)205 encodes Heterochromatin Protein 1 (HP1). These results suggest that the HP1 dosage effect on the P element properties is site-dependent and could involve the structure of the chromatin.
Biosis	99134424
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Erratum	The regulatory properties of autonomous subtelomeric P elements are sensitive to a Suppressor of variegation in Drosophila melanogaster. Ronsseray et al., 1996, Genetics 144(3): 1329 [FBrf0091286]
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Language of publication	English
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Place of publication
Published In
Abbreviation	Genetics
Title	Genetics
Authors
Volume range	1-
Year range	1916-
Page range
Publisher
Place of publication	Austin, TX, etc
Language of publication	English
ISBN/ISSN	0016-6731
CODEN	GENTAE
Data from Reference
Aberrations (1)
	Df(2L)TE29Aa-11
Alleles (10)
	Ecol\lacZ^vas-BC69 Pc¹⁶ Su(var)205¹ Su(var)205² Su(var)205⁴ Su(var)205⁵ Su(z)2^Arp1 sn³ sn^e sn^w
Genes (14)
	Ecol\lacZ Pc Psc Su(var)2-1 Su(var)205 Su(z)2 TAS anon-Ch-P anon-E24 anon-E60 ph-d ph-p sn trx
Insertions (3)
	P{A92}vas^BC69 P{}sn^wa P{}sn^wb
Natural transposons (1)
	P-element