A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Reference Report

Reference
Citation Song, S.U., Gerasimova, T., Kurkulos, M., Boeke, J.D., Corces, V.G. (1994). An env-like protein encoded by a Drosophila retroelement: evidence that gypsy is an infectious retrovirus.  Genes Dev. 8(17): 2046--2057.
FlyBase ID FBrf0076503
Type of publication Research paper
Offprint Available Yes
External Crossreferences
PubMed ID 7958877
PubMed Abstract The gypsy element of Drosophila differs from most LTR retrotransposons in containing a third open reading frame that resembles retroviral env genes. The protein encoded by ORF3 is glycosylated and processed, like all retroviral envelope proteins. The protein is expressed at high levels in fly strains in which gypsy elements are active. In these strains the protein is found primarily in viral particles. When larvae of fly strains in which gypsy is normally inactive are exposed to sucrose gradient fractions containing these particles, a high level of gypsy insertion activity is observed in their progeny. Thus, gypsy has the expected properties of an insect retrovirus.
Biosis 97495598
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Language of publication English
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Abbreviation Genes Dev.
Title Genes & Development
Authors
Volume range 1-
Year range 1987-
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Place of publication Cold Spring Harbor, NY
Language of publication English
ISBN/ISSN 0890-9369
CODEN GEDEEP
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hideAlleles (15)
hideGenes (5)
hideInsertions (11)
hideNatural transposons (1)