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Reference
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| Citation |
Pultz, M.A., Carson, G.S., Baker, B.S. (1994). A genetic analysis of hermaphrodite, a pleiotropic sex determination gene in Drosophila melanogaster. Genetics 136(1): 195--207. |
| FlyBase ID |
FBrf0068639 |
| Type of publication |
Research paper |
| Offprint Available |
Yes |
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External Crossreferences
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| PubMed ID |
8138157 |
| PubMed Abstract |
Sex determination in Drosophila is controlled by a cascade of regulatory genes. Here we describe hermaphrodite (her), a new
component of this regulatory cascade with pleiotropic zygotic and maternal functions. Zygotically, her+ function is required
for female sexual differentiation: when zygotic her+ function is lacking, females are transformed to intersexes. Zygotic her+
function may also play a role in male sexual differentiation. Maternally, her+ function is needed to ensure the viability
of female progeny: a partial loss of her+ function preferentially kills daughters. In addition, her has both zygotic and maternal
functions required for viability in both sexes. Temperature sensitivity prevails for all known her alleles and for all of
the her phenotypes described above, suggesting that her may participate in an intrinsically temperature-sensitive process.
This analysis of four her alleles also indicates that the zygotic and maternal components of of her function are differentially
mutable. We have localized her cytologically to 36A3-36A11.
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| Biosis |
97123840 |
| Zoological record |
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Associated Information
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| Comments |
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| Text of personal communication |
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| Associated files |
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Related Publications
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Also Published As
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Other Reference Information
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| Secondary IDs |
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| Language of publication |
English |
| Additional language(s) of abstract |
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| ISBN |
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| Place of publication |
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Published In
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| Abbreviation |
Genetics |
| Title |
Genetics |
| Authors |
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| Volume range |
1- |
| Year range |
1916- |
| Page range |
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| Publisher |
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| Place of publication |
Austin, TX, etc |
| Language of publication |
English |
| ISBN/ISSN |
0016-6731 |
| CODEN |
GENTAE |
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Data from Reference
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| Aberrations (9)
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| Alleles (5)
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| Genes (2)
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