A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Reference Report

Reference
Citation Kim-Ha, J., Smith, J.L., MacDonald, P.M. (1991). oskar mRNA is localized to the posterior pole of the Drosophila oocyte.  Cell 66(1): 23--35.
FlyBase ID FBrf0053359
Type of publication Research paper
Offprint Available Yes
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PubMed ID 2070416
PubMed Abstract Mutants of the maternal posterior-group genes of Drosophila lack posterior body pattern elements and germ cells, both of which form through the action of determinants localized to the posterior pole of the oocyte. We report that transcripts of one of these genes, oskar, become localized to the posterior pole of oocytes shortly after the oocyte begins to differentiate visibly. Analysis of various posterior-group mutants reveals that localization of oskar mRNA is an early step in the posterior localization pathway. In addition, we find that nonsense oskar mutations disrupt osk mRNA localization, while missense oskar mutations do not.
Biosis 92075569
Zoological record 12900030819
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Language of publication English
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Abbreviation Cell
Title Cell
Authors
Volume range 1-
Year range 1974-
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Publisher Cell Press
Place of publication Cambridge, MA
Language of publication English
ISBN/ISSN 0092-8674
CODEN CELLB5
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