HomeReference Report
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| Citation | Biessmann, H., Mason, J.M. (1988). Progressive loss of DNA sequences from terminal chromosome deficiencies in Drosophila melanogaster. EMBO J. 7: 1081--1086. |
| FlyBase ID | FBrf0047919 |
| Type of publication | Research paper |
| Offprint Available | Yes |
| External Crossreferences | |
| PubMed ID | 2841109 |
| PubMed Abstract | Terminal deficiencies at the tip of the X chromosome can be induced at a high frequency (0.2-0.3%) by irradiating Drosophila females carrying a homozygous mutator (mu-2) with low doses of X-rays. These terminal deficiencies are unstable, since over a period of 3 1/2 years DNA sequences were lost from their distal ends at a rate of 75 bp per generation, presumably due to the absence of a complete wild-type telomeric structure. Breakpoints of these deletions in the 5' upstream regulatory region of the yellow gene, giving rise to a mosaic cuticle pigmentation pattern typical of the y2 type, were used to define the location of tissue-specific cis-acting regulatory elements that are required for body, wing or bristle pigmentation. |
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| Secondary IDs | |
| Language of publication | English |
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| Abbreviation | EMBO J. |
| Title | The EMBO Journal |
| Authors | |
| Volume range | 1- |
| Year range | 1982- |
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| Place of publication | Oxford |
| Language of publication | English |
| ISBN/ISSN | 0261-4189 |
| CODEN | EMJODG |
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Data from Reference
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| Aberrations (249)
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| Alleles (1)
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| Genes (4)
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