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Reference
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| Citation |
Biessmann, H. (1985). Molecular analysis of the yellow gene (y) region of Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 82(): 7369--7373. |
| FlyBase ID |
FBrf0043479 |
| Type of publication |
Research paper |
| Offprint Available |
No |
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External Crossreferences
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| PubMed ID |
3933004 |
| PubMed Abstract |
The yellow gene (y) is involved in pattern-specific melanin pigmentation of the cuticle of the adult fly and of larval mouth
parts of Drosophila melanogaster. I have isolated some 70 kilobases (kb) of contiguous DNA from the y region. Chromosomal
aberrations of y1-type alleles (null alleles) and y2-type alleles that give rise to characteristic pattern mosaicism of pigmentation
were mapped by Southern blot analysis. The y2 allele is associated with the insertion of a "gypsy" transposable element 0.9
kb distal to the putative y coding region. A 3.1-kb region to which breakpoints of all y1-type alleles could be mapped is
homologous to a 2.0-kb polyadenylylated mRNA, the expression of which is specifically regulated in development. This putative
y gene transcript is present at high levels in pupae when melanization of the adult cuticle occurs, but its steady-state levels
change dramatically during development, being highest in late embryos prior to hatching. This suggests that, in addition to
melanin synthesis and/or deposition, the y gene product may have a role in other possibly neural functions.
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| Biosis |
81042615 |
| Zoological record |
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Associated Information
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| Text of personal communication |
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Also Published As
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Other Reference Information
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| Secondary IDs |
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| Language of publication |
English |
| Additional language(s) of abstract |
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| ISBN |
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Published In
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| Abbreviation |
Proc. Natl. Acad. Sci. USA |
| Title |
Proceedings of the National Academy of Sciences of the United States of America |
| Authors |
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| Volume range |
1- |
| Year range |
1915- |
| Page range |
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| Publisher |
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| Place of publication |
Washington, DC |
| Language of publication |
English |
| ISBN/ISSN |
0027-8424 |
| CODEN |
PNASA6 |
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Data from Reference
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| Aberrations (3)
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| Alleles (23)
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| Genes (1)
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