A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Reference Report

Reference
Citation Scott, M.P., Weiner, A.J., Hazelrigg, T., Polisky, B.A., Pirrotta, V., Scalenghe, F., Kaufman, T.C. (1983). The molecular organization of the Antennapedia locus of Drosophila.  Cell 35(): 763--776.
FlyBase ID FBrf0039012
Type of publication Research paper
Offprint Available Yes
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PubMed ID 6418389
PubMed Abstract The Antennapedia complex (ANT-C) of Drosophila is a cluster of genes involved in the regulation of morphogenesis, including at least three homoeotic loci (Antp, Scr, and pb), in which mutations cause switches of cell fates from one developmental pathway to another. We have isolated DNA clones containing most of the ANT-C, a region of about 300 kb. Antp mutations are distributed across more than 100 kb of the ANT-C. Dominant Antp mutations are associated with certain chromosome rearrangements and insertions that interrupt the 100 kb region; other chromosome breaks within the region cause recessive lethality and have no dominant effects. Two prominent transcripts (3.5 and 5.0 kb) are derived from exons within and at the two ends of the 100 kb region.
Biosis 77075144
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Language of publication English
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Abbreviation Cell
Title Cell
Authors
Volume range 1-
Year range 1974-
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Publisher Cell Press
Place of publication Cambridge, MA
Language of publication English
ISBN/ISSN 0092-8674
CODEN CELLB5
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