A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Reference Report

Reference
Citation Roberts, P.A., Broderick, D.J. (1982). Properties and evolutionary potential of newly induced tandem duplications in Drosophila melanogaster.  Genetics 102(): 75--89.
FlyBase ID FBrf0038073
Type of publication Research paper
Offprint Available No
External Crossreferences
PubMed ID 6813191
PubMed Abstract Most of some 33 X-ray-induced duplications recovered as Suppressors of Minute loci proved to be direct tandem duplications. When heterozygous, most duplications were crossover suppressors, and duplications of short to moderate size did not reduce the fitness of their bearers. Crossover suppression by tandem duplication may be attributed to intrastrand foldbacks of the type regularly seen in somatic polytene chromosomes. As a consequence, linkage disequilibrium between duplicated elements and normal chromosomes should be more profound than has been supposed. Tandem duplications appear to be predisposed by reason of frequency of generation, crossover suppression and fitness effects to serve as the primary source of new genes.
Biosis
Zoological record
hide Associated Information
Comments
Text of personal communication
Associated files
hide Related Publications
hide Also Published As
hide Other Reference Information
Secondary IDs
Language of publication English
Additional language(s) of abstract
ISBN
Place of publication
hide Published In
Abbreviation Genetics
Title Genetics
Authors
Volume range 1-
Year range 1916-
Page range
Publisher
Place of publication Austin, TX, etc
Language of publication English
ISBN/ISSN 0016-6731
CODEN GENTAE
hide Data from Reference
hideAberrations (33)
hideAlleles (2)
hideGenes (3)