A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Reference Report

Reference
Citation Ashburner, M. (1982). The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for Alcohol dehydrogenase. III. Hypomorphic and hypermorphic mutations affecting the expression of Hairless. Genetics 101(): 447--459.
FlyBase ID FBrf0038053
Type of publication Research paper
Offprint Available Yes
External Crossreferences
PubMed ID 6816670
PubMed Abstract A lethal locus (l(2)br7;35B6-10), near Adh on chromosome arm 2L of D. melanogaster, is identified with Plunkett's dominant suppressor of Hairless (H). Of eight new alleles, seven act as dominant suppressors of H, the eighth is a dominant enhancer of H. One of the suppressor alleles is both a leaky lethal and a weak suppressor of H. Confirming Nash (1970), deletions of l(2)br7 are dominant suppressors, and duplications are dominant enhancers of H. A simple model is proposed to account for the interaction of l(2)br7 and H, assuming that amorphic (or hypomorphic) alleles of l(2)br7 suppress H and that hypermorphic alleles enhance H.
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Language of publication English
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Abbreviation Genetics
Title Genetics
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Volume range 1-
Year range 1916-
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Place of publication Austin, TX, etc
Language of publication English
ISBN/ISSN 0016-6731
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