Gene Dmel\CG32372

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General Information

Symbol

Dmel\CG32372

Species

D. melanogaster

Name

CG32372

Annotation symbol

CG32372

Feature type

protein_coding_gene

FlyBase ID

FBgn0052372

Created / Updated

2003-12-01/2003-12-01

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

66A3-66A4

Sequence location

3L:7,512,588..7,521,116 [+]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol CG32372 (FBgn0052372). It has the cytological map location 66A3-66A4. Its sequence location is 3L:7512588..7521116. Its molecular function is described as protein binding. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

66A3-66A4

Limits computationally determined from genome sequence between P{PZ}l(3)07217⁰⁸²²³&P{EP}Rac2^EP3118 and P{lacW}Nmt^j1C7

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\CG32372 for information on other features

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG32372-RA

FBtr0076793

NM_168218

3620

817

Additional Transcript Data & Comments

Reported size (kB)

4.7, 4.4 (northern blot)

(Casal and Leptin, 1996)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG32372-PA

FBpp0076507

90.8

817

4.70

NP_729265

AAF50544

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

PANTHER - Protein classification by function, families, and pathways

•

FBgn0052372

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Leucine-rich repeat (IPR001611)

Leucine-rich repeat, typical subtype (IPR003591)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Maps to

Does NOT map to

Identified with

RE09158

(BDGP Project Members, 2000-, Han et al., 2006)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

DEDB - Drosophila exon database: splicing graphs

•

4902

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

embryonic stage | stage 11

mesoderm | segmentally repeated

(Casal and Leptin, 1996)

embryonic stage | stage 17

embryonic/larval fat body

(Casal and Leptin, 1996)

embryonic stage | stage 8

head

(Casal and Leptin, 1996)

embryonic stage | stage >5

mesoderm

(Casal and Leptin, 1996)

embryonic stage | stage 5

mesoderm anlagen

(Casal and Leptin, 1996)

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Microarray Data

Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002)

Untitled Document detailed view

AI134973

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0052372

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0052372

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0052372

BDGP expression data

•

Show all BDGP original images, annotations and embryonic microarray data for CG32372

FlyExpress - Embryonic expression images (BDGP data)

•

Show all FlyExpress processed images for CG32372

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

CG32372^c06895

Sterility

Allele

fertile

CG32372^c06895

Phenotype manifest in

Allele

Classical Alleles ( 2 )

For All Classical Alleles Show

Allele of CG32372	Class	Mutagen	Stocks	Known lesion
CG32372^MB01691			1	--
CG32372^c06895		piggyBac transposase	2	--

Alleles Carried on Transgenic Constructs ( 2 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG32372	Class	Mutagen	Stocks	Known lesion
CG32372^GD5859		in vitro construct \| RNAi in vitro construct \| regulatory fusion	1	Yes
CG32372^hs.PH		in vitro construct \| regulatory fusion	0	Yes

Aneuploid Aberrations

Useful deficiency

Df(3L)pbl-X1

Useful duplication

Dp(3;3)M67C⁺2

Disrupted in

Df(3L)Exel8104

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD5859}

heat-shock construct

P{hs-CG32372.H}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

PBac{PB}CG32372^c06895

insertion of enhancer trap binary system

Mi{ET1}CG32372^MB01691

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 1 )

Molecular Function

CV term

Evidence

References

protein binding

inferred from electronic annotation with InterPro:IPR001611

(FlyBase Curators et al., 2004-)

Biological Process

CV term

Evidence

References

Cellular Component

CV term

Evidence

References

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG32372 allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

64282

Orthologs

Genome-wide drosophilid orthologs

Dana\GF10651

Dere\GG14437

Dgri\GH14894

Dmoj\GI12870

Dper\GL26536

Dpse\GA16850

Dsec\GM14853

Dsim\GD14023

Dvir\GJ13011

Dwil\GK17391

Dyak\GE21627

Curated drosophilid orthologs

Dpse\GA16850

Linkouts

InParanoid orthologs - Eukaryotic orthologs

•

ENSANGP00000010703
Anopheles gambiae (Ensembl)

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 4 )

Harvard

PBac{PB}CG32372^c06895

VDRC

v18977

w¹¹¹⁸; P{GD5859}v18977

Bloomington

17786

w¹¹¹⁸; PBac{PB}CG32372^c06895

23342

y¹ w^67c23; Mi{ET1}CG32372^MB01691

Genomic Clones ( 1 )

BACR10H23

cDNA Clones ( 20 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

RE09158

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Affy Oligo

Linkouts

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0052372

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0052372

Antibody Information

Other Information

Discoverer

Etymology

Identification

Position Effect Variegation Data

Relationship to Other Genes

Source for database identity of

Source for database merge of

Source for merge of: CG14836 CG7545 Annotations CG14836, CG7545 merged as CG32372 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Source for merge of: CG32372 anon-EST:CL1a11 Source for merge of CG32372 anon-EST:CL1a11 was sequence comparison (date:030620).

(FlyBase, 1996-)

Additional comments

Comments About Role

Comments About Molecular Function

ChEST reveals this is a target of Mef2.

(Junion et al., 2005)

Other Comments

Identification: isolated from a subtractive cDNA library enriched in sequences expressed in the mesoderm.

(Casal and Leptin, 1996)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_168218

RefSeq (Proteins)

•

NP_729265

DDBJ / EMBL / GenBank

•

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Leucine-rich repeat (IPR001611)

Leucine-rich repeat, typical subtype (IPR003591)

Linkouts

BDGP expression data

•

Show all BDGP original images, annotations and embryonic microarray data for CG32372

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

64282

DEDB - Drosophila exon database: splicing graphs

•

4902

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0052372

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0052372

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0052372

FlyExpress - Embryonic expression images (BDGP data)

•

FBgn0052372

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0052372

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0052372

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0052372

InParanoid orthologs - Eukaryotic orthologs

•

ENSANGP00000010703
Anopheles gambiae (Ensembl)

PANTHER - Protein classification by function, families, and pathways

•

FBgn0052372

Synonyms & Secondary IDs ( 6 )

Reported As

Symbol Synonym

anon-EST:CL1a11

CG7545

(Junion et al., 2005, )

CG14836

CG32372

(Biemar et al., 2006, Han et al., 2006, Sandmann et al., 2007, Hueber et al., 2007)

CT15760

(Hynes and Zhao, 2000)

(Casal and Leptin, 1996)

Name Synonym

CG32372

Secondary FlyBase IDs

FBgn0019866
FBgn0035794
FBgn0040836

References ( 21 )

Generate a list of

All references relating to this gene ( 21 )

List References by type

Recent research papers ( 4 )

Hueber et al., 2007, Development 134(2): 381--392: Comparative analysis of Hox downstream genes in Drosophila. [FBrf0193798]
Sandmann et al., 2007, Genes Dev. 21(4): 436--449: A core transcriptional network for early mesoderm development in Drosophila melanogaster. [FBrf0195237]
Biemar et al., 2006, Proc. Natl. Acad. Sci. USA 103(34): 12763--12768: Comprehensive identification of Drosophila dorsal-ventral patterning genes using a whole-genome tiling array. [FBrf0191950]
Han et al., 2006, Cell 127(4): 847--858: The fly CAMTA transcription factor potentiates deactivation of rhodopsin, a G protein-coupled light receptor. [FBrf0192912]

Show all research papers ...