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Gene Dmel\stai

General Information
Symbol	Dmel\stai	Species	D. melanogaster
Name	stathmin	Annotation symbol	CG31641
Feature type	protein_coding_gene	FlyBase ID	FBgn0051641
Created / Updated	2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	26B5-26B7	Sequence location	2L:6,100,378..6,123,905 [+]
Map ( GBrowse )	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene stathmin is referred to in FlyBase by the symbol stai (CG31641, FBgn0051641). It has the cytological map location 26B5-26B7. Its sequence location is 2L:6100378..6123905. Its molecular function is described as microtubule binding. It is involved in the biological processes: microtubule-based process; germ cell migration; nervous system development; intracellular signaling cascade. 18 alleles are reported. The phenotypes of these alleles are annotated with: pole cell; embryonic central nervous system; embryonic peripheral nervous system; ventral nerve cord commissure; longitudinal connective. It has 3 annotated transcripts and 3 annotated polypeptides.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 26B5-26B7   Limits computationally determined from genome sequence between P{EP}chicEP713&P{EP}chicEP1095 and P{lacW}Gef26k13720
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology) References Gene Order (overall orientation not stated) References
Gene Model & Products
Please see the GBrowse view of Dmel\stai for information on other features
Comments on Gene Model
	Gene split based on EST and BLASTX data.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) stai-RA FBtr0079198  NM_164684   2059   250 stai-RB FBtr0079197  NM_164683   2215   302 stai-RC FBtr0079196  NM_164682   1864   257
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kD) Length (aa) Theoretical pI RefSeq ID GenBank protein stai-PA   FBpp0078829   28.5   250   10.26     NP_723158   AAF52345 stai-PB   FBpp0078828   34.7   302   10.20     NP_723157   AAN10581 stai-PC   FBpp0078827   29.6   257   8.65     NP_723156   AAN10580
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts	PANTHER - Protein classification by function, families, and pathways • FBgn0051641
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Stathmin (IPR000956)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201179   AA802209   AA979429   AE003612 AAF52345   AE003612 AAN10580   AE003612 AAN10581   AF202773 AAG35627   AF202774 AAG35628   AF202989 AAG35632   AF202990 AAG35633   AI106974   AW941543   AY058786   AY061071 AAL28619   BF493658   BG633629   BG635733   BI141713   BI170474   BI170714   BI172961   BI212883   BI229061   BI230960   BI238390   BI240010   BI241800   BI243744   BI358456   BI363041   BI363051   BI363120   BI374722   BI375236   BI375340   BI376060   BI485418   BI570467   BI570742   BI577340   BI589923   BI611288   BI616930   BI637770   BP541407   BP546938   BP552841   BP553585   BP553586   BP555524   BP555525   BP556450   BP556451   BP558668   BP558669   BP560383   BT001751 AAN71506   CA803225   CA803907   CA804564   CA806856   CO177526   CO182649   CO183620   CO185179   CO186299   CO187657   CO191016   CO195923   CO264044   CO264147   CO265953   CO271474   CO271588   CO272092   CO272419   CO274463   CO275195   CO293661   CO299578   CO301888   CO303683   CO304069   CO306541   CO306727   CO307500   CO308333   CO309025   CO309156   CO309472   CO309845   CO310117   CO310282   CO311356   CO312185   CO314806   CO323634   CO324160   CO324199   CO325698   CO328056   CO330430   CO331099   CO332094   CO340075   CO340361   CO342032   CO343374   CO344073   CZ467571   CZ467882   CZ467883   CZ469182   CZ469183   CZ471284   CZ471285   CZ476364   CZ476365   CZ478049   CZ478565   CZ479369   CZ484934   CZ486218   CZ489334   EC060106   EC066409   EC071889   EC074669   EC078944   EC087703   EC088546   EC197608   EC205071   EC210395   EC211070   EC216586   EC224292   EC224293   EC224989   EC234670   EC235411   EC240548   EC244768   EC245589   EC246626   EC246744   EC247961   EC248767   EC254939   EC256595   EC258544   EC260285   GM04023
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IPK0 Q9GQR3 Q9GQR4 Q9GQR5 Q9GQR6 Q9VMH3
Maps to
Does NOT map to
Identified with	GM04023 (Ozon et al., 2002) LD04103 RH02809 (BDGP Project Members, 2000-) LD33989 (Toba et al., 1999, Seong et al., 2002)
Mapped Features & Mutations
Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here Type Symbol & Location Additional Notes References
External Data
Linkouts	DEDB - Drosophila exon database: splicing graphs • 6615
Crossreferences
Expression Data
FlyBase-Curated Data
Transcript and Protein data	Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
Summary of Transcript Expression
Stage Tissue/Position Reference
Marker for
Subcellular Localization
CV Term
Summary of Polypeptide Expression
Stage Tissue/Position Reference
Marker for
Subcellular Localization
CV Term
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0051641 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • FBgn0051641
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | embryonic stage staidsRNA.cOa lethal, with Scer\GAL4Act5C staiGD8550 semi-lethal, with Scer\GAL429BD staiGS2209 Other Phenotypes Allele wild-type, with Scer\GAL4dpp.blk1 staiGS2209 wild-type, with Scer\GAL4c355 staiGS2209 wild-type, with Scer\GAL4hs.2sev staiGS2209 long lived, with Scer\GAL4hs.PB staiGS2209 Phenotype manifest in Allele pole cell staidsRNA.cOa embryonic central nervous system staidsRNA.cOa embryonic peripheral nervous system staidsRNA.cOa ventral nerve cord commissure staidsRNA.cOa longitudinal connective staidsRNA.cOa chordotonal organ & embryo staidsRNA.cOa
Classical Alleles ( 16 )
For All Classical Alleles Show
Allele of stai Class Mutagen Stocks Known lesion staiB200 0 -- staiC002 1 -- staiGS-A1533 Δ2-3 0 -- staiGS2209 Δ2-3 P-element activity 1 Yes staic01639 piggyBac transposase 2 -- staic01943 piggyBac transposase 0 -- staic02350 piggyBac transposase 1 -- staic04330 piggyBac transposase 0 -- staic07142 piggyBac transposase 1 -- staid08679 P-element activity 1 -- staie00153 piggyBac transposase 0 -- staie00713 piggyBac transposase 0 -- staie01559 piggyBac transposase 0 -- staif02420 piggyBac transposase 1 -- staif03641 piggyBac transposase 1 -- staif06633 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of stai Class Mutagen Stocks Known lesion staiGD8550 in vitro construct | RNAi in vitro construct | regulatory fusion 1 Yes staidsRNA.cOa in vitro construct | RNAi 0 Yes
Aneuploid Aberrations
Useful deficiency	Df(2L)E110
Useful duplicati