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Gene Dmel\CG31121

General Information
Symbol	Dmel\CG31121	Species	D. melanogaster
Name	CG31121	Annotation symbol	CG31121
Feature type	protein_coding_gene	FlyBase ID	FBgn0051121
Created / Updated	2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	96B2-96B4	Sequence location	3R:20,707,180..20,720,327 [-]
Map ( GBrowse )	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol CG31121 (FBgn0051121). It has the cytological map location 96B2-96B4. Its sequence location is 3R:20707180..20720327. Its molecular function is described as: ATPase activity, coupled to transmembrane movement of substances; transporter activity; ATP binding. It is involved in the biological process transport. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 96B2-96B4   Limits computationally determined from genome sequence between P{EP}CycB3EP3127 and P{PZ}ssh01207
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology) References Gene Order (overall orientation not stated) References
Gene Model & Products
Please see the GBrowse view of Dmel\CG31121 for information on other features
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG31121-RA FBtr0084723  NM_170179   3304   911 CG31121-RB FBtr0084724  NM_170180   3144   911
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kD) Length (aa) Theoretical pI RefSeq ID GenBank protein CG31121-PA   FBpp0084098   99.7   911   8.13     NP_733058   AAF56359 CG31121-PB   FBpp0084099   99.7   911   8.13     NP_733059   AAF56360
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts	PANTHER - Protein classification by function, families, and pathways • FBgn0051121
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • ABC transporter-like (IPR003439) ABC-2 type transporter (IPR013525)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE003749 AAF56359   AE003749 AAF56360   AI258231   AI388478   AY089579 AAL90317   AY118799 AAM50659   BI165002   BI169884   CK657465   CO267395   CO268053   CO278765   CO315792   CO322537   CO339183   CZ470191   CZ490060   EC052803   EC053276   EC054257   EC054768   EC055193   EC057928   EC077459   EC082447   EC083958   EC084623   EC089289   EC230705   EC235571   EC246490   EC258889
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8SXK9 Q9VC17 Q0KI14
Maps to
Does NOT map to
Identified with	GH19411 RE11181 (BDGP Project Members, 2000-)
Mapped Features & Mutations
Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here Type Symbol & Location Additional Notes References
External Data
Linkouts	DEDB - Drosophila exon database: splicing graphs • 10670
Crossreferences
Expression Data
FlyBase-Curated Data
Transcript and Protein data	Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
Summary of Transcript Expression
Stage Tissue/Position Reference
Marker for
Subcellular Localization
CV Term
Summary of Polypeptide Expression
Stage Tissue/Position Reference
Marker for
Subcellular Localization
CV Term
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0051121 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • FBgn0051121 GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies • FBgn0051121 BDGP expression data • Show all BDGP original images, annotations and embryonic microarray data for CG31121 FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG31121 Stage(s) 4-6 Stage(s) 9-10 Stage(s) 11-12 Stage(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG31121d06890 Sterility Allele fertile CG31121d06890 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of CG31121 Class Mutagen Stocks Known lesion CG31121MB01633 1 -- CG31121c05696 piggyBac transposase 1 -- CG31121d06890 P-element activity 2 -- CG31121f07249 piggyBac transposase 2 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG31121 Class Mutagen Stocks Known lesion CG31121GD255 in vitro construct | RNAi in vitro construct | regulatory fusion 2 Yes
Aneuploid Aberrations
Useful deficiency	Df(3R)96B
Useful duplication	Dp(3;3)Su8
Disrupted in	Df(3R)Exel6200 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD255} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{PB}CG31121c05696 NA PBac{WH}CG31121f07249 NA insertion of enhancer trap binary system Mi{ET1}CG31121MB01633 No insertion of mobile activating element P{XP}CG31121d06890 NA
Related Comments
	Please look at the allele reports for the complete phenotype data
Gene Ontology: Function, Process & Cellular Component ( 5 )
Molecular Function
CV term Evidence References
ATP binding inferred from electronic annotation with InterPro:IPR003439 (FlyBase Curators et al., 2004-)
ATPase activity, coupled to transmembrane movement of substances inferred from sequence or structural similarity with UniProtKB:Q9H221 (FlyBase, 1992-)
transporter activity inferred from sequence or structural similarity with UniProtKB:Q9H221 (FlyBase, 1992-)
Biological Process
CV term Evidence References
transport inferred from sequence or structural similarity with UniProtKB:Q9H221 (FlyBase, 1992-)
Cellular Component
CV term Evidence References
ATP-binding cassette (ABC) transporter complex inferred from sequence or structural similarity with UniProtKB:Q9H221 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	protein_coding_gene   nuclear_gene
Interactions & Pathways
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG31121 allele Gene References
External Data
Linkouts	BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions • 67898
Orthologs
Genome-wide drosophilid orthologs	Dana\GF18680 Dere\GG12304 Dgri\GH14262 Dmoj\GI23153 Dper\GL23078 Dpse\GA16025 Dsec\GM23447 Dsim\GD18254 Dvir\GJ10456 Dwil\GK14275 Dyak\GE10759
Curated drosophilid orthologs	Dpse\GA16025
Linkouts	InParanoid orthologs - Eukaryotic orthologs • ENSANGP00000019849 Anopheles gambiae (Ensembl)
Functional Complementation between Species
Inter-Species Misexpression Data
Produces phenotype in
Produces NO phenotype in
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Harvard	- P{XP}CG31121d06890 - PBac{PB}CG31121c05696 - PBac{WH}CG31121f07249
VDRC	v43980 w1118; P{GD255}v43980 v43981 w1118; P{GD255}v43981
Bloomington	19254 w1118; P{XP}CG31121d06890 23749 y1 w67c23; Mi{ET1}CG31121MB01633 19061 w1118; PBac{WH}CG31121f07249/TM6B, Tb1
Genomic Clones ( 1 )
	BACR33F18
cDNA Clones ( 16 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH19411 RE11181
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP23782 LP01372 RE04794
Other clones	EC053276 EK262449 EP01028 EK131518 EC054257 EC055193 EK090033 EK150024 EC054768 EK188333 EC052803
RNAi & Array Information
Affy Oligo
Linkouts	DRSC - RNAi screening (Harvard): high-throughput cell culture data and design • FBgn0051121 GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data • FBgn0051121
Antibody Information
Other Information
Discoverer
Etymology
Identification
Position Effect Variegation Data
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG18633 CG18655 Annotations CG18633, CG18655 merged as CG31121 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003) Source for merge of: CG18655 CG11764 Source for merge of: CG31121 BcDNA:GH19411 Source for merge of CG18655 CG11764 was sequence comparison (date:001104). Source for merge of CG31121 BcDNA:GH19411 was a shared cDNA (date:030728). (FlyBase, 1996-)
Additional comments
Comments About Role
Comments About Molecular Function
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_170179 NM_170180 RefSeq (Proteins) • NP_733058 NP_733059 DDBJ / EMBL / GenBank • AE003749 AAF56359 AAF56360 AI388478 AY089579 AAL90317 AY118799 AAM50659 BI169884 CZ470191 CZ490060 UniProtKB/TrEMBL • Q8SXK9 Q9VC17 Q0KI14
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • ABC transporter-like (IPR003439) ABC-2 type transporter (IPR013525)
Linkouts
	BDGP expression data • Show all BDGP original images, annotations and embryonic microarray data for CG31121 BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions • 67898 DEDB - Drosophila exon database: splicing graphs • 10670 DRSC - RNAi screening (Harvard): high-throughput cell culture data and design • FBgn0051121 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0051121 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • FBgn0051121 FlyExpress - Embryonic expression images (BDGP data) • FBgn0051121 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0051121 GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies • FBgn0051121 GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data • FBgn0051121 InParanoid orthologs - Eukaryotic orthologs • ENSANGP00000019849 Anopheles gambiae (Ensembl) PANTHER - Protein classification by function, families, and pathways • FBgn0051121
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	BcDNA:GH19411   CG11764   CG18633 (Dean et al., 2001, ) CG18655   CG31121
Name Synonym	CG31121
Secondary FlyBase IDs
	FBgn0039242 FBgn0039243 FBgn0042211 FBgn0063237
References ( 15 )
Supplementary material	Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Review	Dean et al., 2001, Genome Res. 11: 1156--1166 The human ATP-binding cassette (ABC) transporter superfamily. [FBrf0159553]
Personal communication to FlyBase	Bellen, 2007.2.1, Batch706FlyBase_cyto_update.xml Batch706FlyBase_cyto_update.xml [FBrf0191799] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886] FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Ketchum, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126677]