Gene Dmel\CG30183

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General Information

Symbol

Dmel\CG30183

Species

D. melanogaster

Name

CG30183

Annotation symbol

CG30183

Feature type

protein_coding_gene

FlyBase ID

FBgn0050183

Created / Updated

2003-12-01/2007-03-20

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

59F6-59F6

Sequence location

2R:19,578,314..19,585,198 [-]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol CG30183 (FBgn0050183). It has the cytological map location 59F6. Its sequence location is 2R:19578314..19585198. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

59F6-59F6

Limits computationally determined from genome sequence between P{PZ}apt⁰³⁰⁴¹ and P{EP}egl^EP938

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\CG30183 for information on other features

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG30183-RA

FBtr0072099

NM_137975

4768

1555

CG30183-RB

FBtr0273300

3316

1065

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG30183-PA

FBpp0072008

173.8

1555

9.12

NP_611819

CG30183-PB

FBpp0271808

119.3

1065

9.63

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

PANTHER - Protein classification by function, families, and pathways

•

FBgn0050183

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Pleckstrin-like (IPR001849)

Pleckstrin homology-type (IPR011993)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Maps to

Does NOT map to

Identified with

AT15782

(BDGP Project Members, 2000-)

bs18b03

(Oliver, 2001.8.16)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

DEDB - Drosophila exon database: splicing graphs

•

1606

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0050183

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0050183

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0050183

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of CG30183	Class	Mutagen	Stocks	Known lesion
CG30183^KG08388		P-element activity	1	--

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG30183	Class	Mutagen	Stocks	Known lesion
CG30183^GD10018		in vitro construct \| RNAi in vitro construct \| regulatory fusion	2	Yes

Aneuploid Aberrations

Useful deficiency

Df(2R)egl2

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD10018}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

P{SUPor-P}CG30183^KG08388

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 0 )

Molecular Function

CV term

Evidence

References

Biological Process

CV term

Evidence

References

Cellular Component

CV term

Evidence

References

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG30183 allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

63347

Orthologs

Genome-wide drosophilid orthologs

Dana\GF11828

Dere\GG20008

Dgri\GH21554

Dmoj\GI19526

Dper\GL17593

Dpse\GA15707

Dsec\GM15520

Dsim\GD25024

Dvir\GJ21095

Dwil\GK23171

Dyak\GE11544

Curated drosophilid orthologs

Dpse\GA15707

Linkouts

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 3 )

VDRC

v25594

w¹¹¹⁸; P{GD10018}v25594

v25595

w¹¹¹⁸; P{GD10018}v25595

Bloomington

14951

y¹; P{SUPor-P}CG30183^KG08388/CyO; ry⁵⁰⁶

Genomic Clones ( 2 )

cDNA Clones ( 18 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

AT15782

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Affy Oligo

Linkouts

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0050183

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0050183

Antibody Information

Other Information

Discoverer

Etymology

Identification

Position Effect Variegation Data

Relationship to Other Genes

Source for database identity of

Source for database merge of

Source for merge of: CG4093 CG4530 Annotations CG4093, CG4530 merged as CG30183 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Additional comments

Comments About Role

Comments About Molecular Function

Other Comments

dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R⁺ cell morphology.

(Kiger et al., 2003)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_137975

RefSeq (Proteins)

•

NP_611819

DDBJ / EMBL / GenBank

•

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Pleckstrin-like (IPR001849)

Pleckstrin homology-type (IPR011993)

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

63347

DEDB - Drosophila exon database: splicing graphs

•

1606

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0050183

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0050183

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0050183

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0050183

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0050183

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0050183

PANTHER - Protein classification by function, families, and pathways

•

FBgn0050183

Synonyms & Secondary IDs ( 3 )

Reported As

Symbol Synonym

CG4093

CG4530

CG30183

Name Synonym

CG30183

Secondary FlyBase IDs

FBgn0034891
FBgn0034892

References ( 9 )

Supplementary material

Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]
Kiger et al., 2003, J. Biol. 2(4):: Additional data file 1: The gene identity and primer sequences for dsRNAs used in the RNAi screens. [FBrf0174231]

Personal communication to FlyBase

Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348).: File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]

FlyBase analysis

FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome.: Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886]
FlyBase, 1992-, FlyBase curation: FlyBase curation. [FBrf0105495]

Computer file

Gene Disruption Project members, 2001-, [title not yet available]: [title not yet available] [FBrf0132177]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.: Berkeley Drosophila Genome Project. [FBrf0125078]

Automatic genome annotation

FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126705]