A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\Tsp97E

General Information
SymbolDmel\Tsp97ESpeciesD. melanogaster
NameTetraspanin 97EAnnotation symbolCG6323
Feature typeprotein_coding_geneFlyBase IDFBgn0039465
Created / Updated2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)3RRecombination map
Cytogenetic map97D11-97D11Sequence location3R:22,787,446..22,790,547 [-]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
The gene Tetraspanin 97E is referred to in FlyBase by the symbol Tsp97E (CG6323, FBgn0039465). It has the cytological map location 97D11. Its sequence location is 3R:22787446..22790547. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
97D11-97D11  
Limits computationally determined from genome sequence between P{PZ}sda03884 and P{PZ}btzrL203  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
97E-97E
 
(Todres, 2000.6.1)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Please see the GBrowse view of Dmel\Tsp97E for information on other features
detailed view FBtr0273309 FBtr0273310 FBtr0085082 FBtr0085081 FBpp0271817 FBpp0271818 FBpp0084454 FBpp0084453 FBti0042536
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
Tsp97E-RA
FBtr0085082
 NM_079800
  1442
  228
Tsp97E-RC
FBtr0273309
 
  1021
  144
Tsp97E-RD
FBtr0273310
 
  1319
  221
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
Tsp97E-PA  
FBpp0084454  
25.0  
228  
6.62  
  NP_524524
 
Tsp97E-PC  
FBpp0271817  
16.0  
144  
4.60  
 
 
Tsp97E-PD  
FBpp0271818  
24.1  
221  
6.68  
 
 
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
•
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
CD9/CD37/CD63 antigen (IPR000301)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AA201125
 
AA201875
 
AA949943
 
AA952241
 
AE003758
AAF56643
 
AE003758
AAN14096
 
AF274020
AAF90146
 
AI260172
 
AI455060
 
AI514708
 
AI514801
 
AI516465
 
AI517808
 
AY060360
AAL25399
 
BG632408
 
BG637067
 
BI212916
 
BI229819
 
BI229827
 
BI240332
 
BI240952
 
BI243952
 
BI486396
 
BI487172
 
BI580414
 
BI628806
 
BI638333
 
BQ103659
 
CO177373
 
CO266079
 
CO266349
 
CO272560
 
CO277391
 
CO283679
 
CO283682
 
CO296400
 
CO302527
 
CO302844
 
CO305644
 
CO327057
 
CO329279
 
CO333847
 
CO343444
 
EC053815
 
EC054330
 
EC055211
 
EC060348
 
EC083194
 
EC195662
 
EC201723
 
EC205421
 
EC210400
 
EC220163
 
EC226305
 
EC233486
 
EC237266
 
EC239312
 
EC246227
 
EC246387
 
EC247168
 
EC260180
 
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    (BDGP Project Members, 2000-, Todres, 2000.6.1)
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Phenotype manifest in
        Allele
        hide Classical Alleles ( 0 )
        For All Classical Alleles Show

        Allele of Tsp97EClassMutagenStocksKnown lesion
        hide Alleles Carried on Transgenic Constructs ( 1 )
        For All Alleles Carried on Transgenic Constructs Show

        Allele of Tsp97EClassMutagenStocksKnown lesion
        Tsp97EGD3101 Yes
        hide Aneuploid Aberrations
        Useful deficiency
         
        Useful duplication
         
        hide Transgenic Constructs & Insertions
        Transgenic Constructs
        Type of construct
        Name
        Expression data
        UAS construct
        P{GD310}
        NA
        Insertions
        Type of insertions
        Name
        Expression data
        hide Related Comments
        Please look at the allele reports for the complete phenotype data
        hide Gene Ontology: Function, Process & Cellular Component ( 1 )
        hide Molecular Function
        CV term
        Evidence
        References
        hide Biological Process
        CV term
        Evidence
        References
        hide Cellular Component
        CV term
        Evidence
        References
        integral to membrane
        inferred from sequence or structural similarity
        (Todres et al., 2000)
        inferred from electronic annotation with InterPro:IPR000301
        (FlyBase Curators et al., 2004-)
        hide Sequence Ontology: Class of Gene
        protein_coding_gene
         
        nuclear_gene
         
        hide Interactions & Pathways
        hide Summary of Genetic Interactions
        Interacts with
        Please look at the allele data for full details of the genetic interactions
        Tsp97E allele
        Gene
        References
        hide External Data
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        hide Orthologs
        Genome-wide drosophilid orthologs
        Curated drosophilid orthologs
         
        Linkouts
        InParanoid orthologs - Eukaryotic orthologs
        •
        hide Functional Complementation between Species
        hide Inter-Species Misexpression Data
        Produces phenotype in
        Produces NO phenotype in
        hide Stocks & Reagents
        hide Stocks Listed in FlyBase ( 1 )
        VDRC
        v4391
        w1118; P{GD310}v4391
        hide Genomic Clones ( 1 )
        hide cDNA Clones ( 42 )
        Please Note
        This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
        cDNA Clones, Fully Sequenced
        BDGP DGC clones
        Other clones
        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        hide RNAi & Array Information
        Affy Oligo
        Linkouts
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        hide Antibody Information
        hide Other Information
        hide Discoverer
        hide Etymology
        hide Identification
        hide Position Effect Variegation Data
        hide Relationship to Other Genes
        Source for database identity of
        Source for identity of: Tsp97E CG6323 Source for identity of Tsp97E CG6323 was sequence comparison (date:000815).
        (FlyBase, 1996-)
        Source for database merge of
        Additional comments
        hide Comments About Role
        hide Comments About Molecular Function
        hide Other Comments
        hide External Crossreferences & Linkouts
        Sequence Crossreferences
        RefSeq (Transcripts)
        •
        RefSeq (Proteins)
        •
        DDBJ / EMBL / GenBank
        •
        UniProtKB/TrEMBL
        •
        Other Crossreferences
        InterPro domains - A database of protein families, domains, and functional sites
        •
        CD9/CD37/CD63 antigen (IPR000301)
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        DEDB - Drosophila exon database: splicing graphs
        •
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        InParanoid orthologs - Eukaryotic orthologs
        •
        PANTHER - Protein classification by function, families, and pathways
        •
        University of Chicago Dev. Expression
        •
        hide Synonyms & Secondary IDs ( 4 )
        Reported As
        Symbol Synonym
        CG6323
        (Schneider et al., 2004, Fradkin et al., 2002, Todres et al., 2000, )
        Dm.Tsp97E
        (Todres et al., 2000)
        Tsp97E
         
        Name Synonym
        Tetraspanin 97E
        (Todres, 2000.6.1)
        Secondary FlyBase IDs
          hide References ( 12 )
          Research paper
          Schneider et al., 2004, Proc. Natl. Acad. Sci. USA 101(26): 9584--9589
          Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila. [FBrf0179434]
          Fradkin et al., 2002, Proc. Natl. Acad. Sci. USA 99(21): 13663--13668
          Genomewide analysis of the Drosophila tetraspanins reveals a subset with similar function in the formation of the embryonic synapse. [FBrf0152316]
          Todres et al., 2000, Insect Molec. Biol. 9(6): 581--590
          The tetraspanin superfamily in insects. [FBrf0132356]
          Supplementary material
          Giot et al., 2003, Science 302(5651):
          Tables S1 to S7. [FBrf0166452]
          Personal communication to FlyBase
          Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center
          RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
          FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.
          Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
          FlyBase analysis
          FlyBase, 1996-, FlyBase inference based on genome sequence analysis.
          FlyBase inference based on genome sequence analysis. [FBrf0104946]
          FlyBase, 1992-, FlyBase curation
          FlyBase curation. [FBrf0105495]
          DNA/RNA sequence record
          Todres, 2000.6.1, GenBank/EMBL/DDBJ: AF274020
          Drosophila melanogaster tetraspanin 97E mRNA, complete cds. [FBrf0130971]
          Computer file
          BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.
          Berkeley Drosophila Genome Project. [FBrf0125078]
          Automatic genome annotation
          FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.]
          [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
          Curated genome annotation
          Mount, 1999.11, [Annotations performed at the Celera Jamboreee.]
          [Annotations performed at the Celera Jamboreee.] [FBrf0126690]