A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\CG18012

General Information
SymbolDmel\CG18012SpeciesD. melanogaster
NameCG18012Annotation symbolCG18012
Feature typeprotein_coding_geneFlyBase IDFBgn0038552
Created / Updated2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)3RRecombination map
Cytogenetic map90C6-90C6Sequence location3R:13,635,117..13,636,854 [-]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
This gene is referred to in FlyBase by the symbol CG18012 (FBgn0038552). It has the cytological map location 90C6. Its sequence location is 3R:13635117..13636854. Its molecular function is described as beta-1,4-mannosyltransferase activity. It is involved in the biological process protein amino acid glycosylation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
90C6-90C6  
Limits computationally determined from genome sequence between P{PZ}l(3)0788207882 and P{EP}cpoEP3679  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Please see the GBrowse view of Dmel\CG18012 for information on other features
detailed view FBtr0083524 FBtr0083523 FBtr0083514 FBpp0082948 FBpp0082947 FBti0041907 FBti0028028 FBti0072508 FBti0039456 FBti0059332 FBti0054418
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
CG18012-RA
FBtr0083523
 NM_142405
  1619
  446
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
CG18012-PA  
FBpp0082947  
51.0  
446  
7.01  
  NP_650662
  AAF55475
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
•
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
Glycosyl transferase, group 1 (IPR001296)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AA141173
 
AA817319
 
AA978980
 
AE003719
AAF55475
 
AI257231
 
AI455280
 
AI534999
 
AY118918
AAM50778
 
BF501372
 
BF505135
 
BG636795
 
BI212479
 
BI229605
 
BI358294
 
BI372508
 
BI564378
 
BI567082
 
BI567863
 
BI568215
 
BI572629
 
BI572673
 
BI575391
 
BI575467
 
BI575731
 
BI576603
 
BI583872
 
BI586036
 
BI586061
 
BI588384
 
BI591159
 
BI593249
 
BI610402
 
BI610786
 
BI626612
 
BI630060
 
BI634223
 
BI639239
 
CK660029
 
CO190675
 
CO285174
 
CO285652
 
CO301015
 
CO335594
 
EC057181
 
EC069512
 
EC074121
 
EC200380
 
EC218297
 
EC223305
 
EC234454
 
EC262798
 
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    (BDGP Project Members, 2000-)
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Phenotype manifest in
        Allele
        hide Classical Alleles ( 1 )
        For All Classical Alleles Show

        Allele of CG18012ClassMutagenStocksKnown lesion
        CG18012DG306111 --
        hide Alleles Carried on Transgenic Constructs ( 1 )
        For All Alleles Carried on Transgenic Constructs Show

        Allele of CG18012ClassMutagenStocksKnown lesion
        CG18012GD95001 Yes
        hide Aneuploid Aberrations
        Useful deficiency
         
        Useful duplication
         
        hide Transgenic Constructs & Insertions
        Transgenic Constructs
        Type of construct
        Name
        Expression data
        UAS construct
        P{GD9500}
        NA
        Insertions
        Type of insertions
        Name
        Expression data
        miscellaneous insertions
        P{wHy}CG18012DG30611
        NA
        insertion of mobile activating element
        P{Mae-UAS.6.11}UY2517UY2517
        NA
        hide Related Comments
        Please look at the allele reports for the complete phenotype data
        hide Gene Ontology: Function, Process & Cellular Component ( 2 )
        hide Molecular Function
        CV term
        Evidence
        References
        beta-1,4-mannosyltransferase activity
        inferred from sequence or structural similarity with SGD_LOCUS:ALG1; SGD:S0000314
        (FlyBase, 1992-)
        hide Biological Process
        CV term
        Evidence
        References
        protein amino acid glycosylation
        inferred from sequence or structural similarity with SGD_LOCUS:ALG1; SGD:S0000314
        (FlyBase, 1992-)
        hide Cellular Component
        CV term
        Evidence
        References
        hide Sequence Ontology: Class of Gene
        protein_coding_gene
         
        nuclear_gene
         
        hide Interactions & Pathways
        hide Summary of Genetic Interactions
        Interacts with
        Please look at the allele data for full details of the genetic interactions
        CG18012 allele
        Gene
        References
        hide External Data
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        hide Orthologs
        Genome-wide drosophilid orthologs
        Curated drosophilid orthologs
        Linkouts
        InParanoid orthologs - Eukaryotic orthologs
        •
        hide Functional Complementation between Species
        hide Inter-Species Misexpression Data
        Produces phenotype in
        Produces NO phenotype in
        hide Stocks & Reagents
        hide Stocks Listed in FlyBase ( 3 )
        VDRC
        v20580
        w1118; P{GD9500}v20580
        Bloomington
        6765
        y1 w*; P{Mae-UAS.6.11}UY2517UY2517
        21333
        y1 w67c23; P{wHy}CG18012DG30611/TM3, Sb1 Ser1
        hide Genomic Clones ( 2 )
        hide cDNA Clones ( 40 )
        Please Note
        This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
        cDNA Clones, Fully Sequenced
        BDGP DGC clones
        Other clones
        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        hide RNAi & Array Information
        Affy Oligo
        Linkouts
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        hide Antibody Information
        hide Other Information
        hide Discoverer
        hide Etymology
        hide Identification
        hide Position Effect Variegation Data
        hide Relationship to Other Genes
        Source for database identity of
        Source for database merge of
        Additional comments
        hide Comments About Role
        hide Comments About Molecular Function
        hide Other Comments
        hide External Crossreferences & Linkouts
        Sequence Crossreferences
        RefSeq (Transcripts)
        •
        RefSeq (Proteins)
        •
        DDBJ / EMBL / GenBank
        •
        UniProtKB/TrEMBL
        •
        Other Crossreferences
        InterPro domains - A database of protein families, domains, and functional sites
        •
        Glycosyl transferase, group 1 (IPR001296)
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        DEDB - Drosophila exon database: splicing graphs
        •
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        InParanoid orthologs - Eukaryotic orthologs
        •
        PANTHER - Protein classification by function, families, and pathways
        •
        hide Synonyms & Secondary IDs ( 1 )
        Reported As
        Symbol Synonym
        CG18012
         
        Name Synonym
        CG18012
         
        Secondary FlyBase IDs
          hide References ( 10 )
          Research paper
          Bjorklund et al., 2006, Nature 439(7079): 1009--1013
          Identification of pathways regulating cell size and cell-cycle progression by RNAi. [FBrf0191233]
          Orian et al., 2003, Genes Dev. 17(9): 1101--1114
          Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. [FBrf0158942]
          Monnier et al., 2002, genesis 34(1-2): 76--79
          Modulation of oxidative stress resistance in Drosophila melanogaster by gene overexpression. [FBrf0152382]
          Supplementary material
          Giot et al., 2003, Science 302(5651):
          Tables S1 to S7. [FBrf0166452]
          Personal communication to FlyBase
          BDGP TI submission, 2008.3.31, DG.xml
          DG.xml [FBrf0204101]
          Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center
          RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
          Myrick et al., 2005.5.16, Deletion Generator Project genomic insertion collection.
          Deletion Generator Project genomic insertion collection. [FBrf0188490]
          FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.
          Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
          FlyBase analysis
          FlyBase, 1992-, FlyBase curation
          FlyBase curation. [FBrf0105495]
          Computer file
          BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.
          Berkeley Drosophila Genome Project. [FBrf0125078]