Gene Dmel\CG5319

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General Information

Symbol

Dmel\CG5319

Species

D. melanogaster

Name

CG5319

Annotation symbol

CG5319

Feature type

protein_coding_gene

FlyBase ID

FBgn0038501

Created / Updated

2003-12-01/2007-03-20

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

90A4-90A4

Sequence location

3R:13,211,626..13,215,988 [+]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol CG5319 (FBgn0038501). It has the cytological map location 90A4. Its sequence location is 3R:13211626..13215988. Its molecular function is described as protein binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

90A4-90A4

Limits computationally determined from genome sequence between P{EP}CG5208^EP562&P{EP}Dad^EP3196 and P{PZ}l(3)07882⁰⁷⁸⁸²

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\CG5319 for information on other features

Comments on Gene Model

EST data suggest additional 3' exon(s)

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG5319-RA

FBtr0083435

NM_142361

3525

677

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG5319-PA

FBpp0082876

72.0

677

5.97

NP_650618

AAF55411

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

PANTHER - Protein classification by function, families, and pathways

•

FBgn0038501

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

BTB/POZ-like (IPR000210)

BTB/Kelch-associated (IPR011705)

PHR (IPR012983)

BTB/POZ (IPR013069)

BTB/POZ fold (IPR011333)

Kelch related (IPR013089)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Maps to

Does NOT map to

Identified with

LD01876

(BDGP Project Members, 2000-)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

DEDB - Drosophila exon database: splicing graphs

•

9779

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0038501

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0038501

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0038501

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of CG5319	Class	Mutagen	Stocks	Known lesion
CG5319^KG02251		P-element activity	1	--

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG5319	Class	Mutagen	Stocks	Known lesion
CG5319^GD11604		in vitro construct \| RNAi in vitro construct \| regulatory fusion	2	Yes

Aneuploid Aberrations

Useful deficiency

Df(3R)DG2

Useful duplication

Dp(3;3)C123.3

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD11604}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

P{SUPor-P}CG5319^KG02251

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 1 )

Molecular Function

CV term

Evidence

References

protein binding

inferred from electronic annotation with InterPro:IPR000210, InterPro:IPR011333, InterPro:IPR013069

(FlyBase Curators et al., 2004-)

Biological Process

CV term

Evidence

References

Cellular Component

CV term

Evidence

References

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG5319 allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

67126

Orthologs

Genome-wide drosophilid orthologs

Dana\GF18143

Dere\GG22159

Dgri\GH13476

Dmoj\GI24778

Dper\GL23567

Dpse\GA18801

Dsec\GM15225

Dsim\GD19151

Dvir\GJ24428

Dwil\GK11641

Dyak\GE10124

Curated drosophilid orthologs

Dpse\GA18801

Linkouts

InParanoid orthologs - Eukaryotic orthologs

•

ENSANGP00000013336
Anopheles gambiae (Ensembl)
ENSBTAP00000025703
Bos taurus (Ensembl)
ENSCAFP00000008380
Canis familiaris (Ensembl)
ENSCINP00000008658
Ciona intestinalis (Ensembl)
NEWSINFRUP00000164497
Takifugu rubripes (Ensembl)
ENSGALP00000032570
Gallus gallus (Ensembl)
ENSP00000337054
Homo sapiens (Ensembl)
ENSMMUP00000024883
Macaca mulatta (Ensembl)
ENSMODP00000006059
Monodelphis domestica (Ensembl)
ENSPTRP00000022732
Pan troglodytes (Ensembl)
ENSRNOP00000010835
Rattus norvegicus (Ensembl)
GSTENP00004694001
Tetraodon nigroviridis (Ensembl)
ENSXETP00000048827
Xenopus tropicalis (Ensembl)
WBGene00028486
Caenorhabditis briggsae (Wormbase)
WBGene00006415
Caenorhabditis elegans (Wormbase)
MGI:2385155
Mus musculus (Informatics)

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 3 )

VDRC

v34986

w¹¹¹⁸; P{GD11604}v34986

v34987

w¹¹¹⁸; P{GD11604}v34987

Bloomington

15099

y¹; ry⁵⁰⁶ P{SUPor-P}CG5319^KG02251/TM3, Sb¹ Ser¹

Genomic Clones ( 2 )

cDNA Clones ( 20 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

LD01876

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Affy Oligo

Linkouts

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0038501

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0038501

Antibody Information

Other Information

Discoverer

Etymology

Identification

Position Effect Variegation Data

Relationship to Other Genes

Source for database identity of

Source for database merge of

Source for merge of: CG5319 anon-WO0118547.289 Source for merge of CG5319 anon-WO0118547.289 was sequence comparison (date:051113).

(FlyBase, 1996-)

Additional comments

Comments About Role

Comments About Molecular Function

Other Comments

Area matching Drosophila EST AA264635.

(Davies, 2001.3.15)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_142361

RefSeq (Proteins)

•

NP_650618

DDBJ / EMBL / GenBank

•

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

BTB/POZ-like (IPR000210)

BTB/Kelch-associated (IPR011705)

PHR (IPR012983)

BTB/POZ (IPR013069)

BTB/POZ fold (IPR011333)

Kelch related (IPR013089)

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

67126

DEDB - Drosophila exon database: splicing graphs

•

9779

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0038501

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0038501

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0038501

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0038501

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0038501

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0038501

InParanoid orthologs - Eukaryotic orthologs

•

ENSANGP00000013336
Anopheles gambiae (Ensembl)
ENSBTAP00000025703
Bos taurus (Ensembl)
ENSCAFP00000008380
Canis familiaris (Ensembl)
ENSCINP00000008658
Ciona intestinalis (Ensembl)
NEWSINFRUP00000164497
Takifugu rubripes (Ensembl)
ENSGALP00000032570
Gallus gallus (Ensembl)
ENSP00000337054
Homo sapiens (Ensembl)
ENSMMUP00000024883
Macaca mulatta (Ensembl)
ENSMODP00000006059
Monodelphis domestica (Ensembl)
ENSPTRP00000022732
Pan troglodytes (Ensembl)
ENSRNOP00000010835
Rattus norvegicus (Ensembl)
GSTENP00004694001
Tetraodon nigroviridis (Ensembl)
ENSXETP00000048827
Xenopus tropicalis (Ensembl)
WBGene00028486
Caenorhabditis briggsae (Wormbase)
WBGene00006415
Caenorhabditis elegans (Wormbase)
MGI:2385155
Mus musculus (Informatics)

PANTHER - Protein classification by function, families, and pathways

•

FBgn0038501

Synonyms & Secondary IDs ( 2 )

Reported As

Symbol Synonym

anon-WO0118547.289

CG5319

(Mack et al., 2006)

Name Synonym

CG5319

Secondary FlyBase IDs

FBgn0062117

References ( 10 )

Research paper

Mack et al., 2006, Proc. Natl. Acad. Sci. USA 103(27): 10358--10363: Mating-responsive genes in reproductive tissues of female Drosophila melanogaster. [FBrf0194111]

Personal communication to FlyBase

Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]

FlyBase analysis

FlyBase, 1996-, FlyBase inference based on genome sequence analysis.: FlyBase inference based on genome sequence analysis. [FBrf0104946]
FlyBase, 1992-, FlyBase curation: FlyBase curation. [FBrf0105495]

DNA/RNA sequence record

Davies, 2001.3.15, GenBank/EMBL/DDBJ: AX094165: Sequence 289 from Patent WO0118547. [FBrf0149989]

Patent

Davies et al., 2001, World Patent 0118547:: Essential genes and assays relating thereto. [FBrf0199103]

Computer file

Gene Disruption Project members, 2001-, [title not yet available]: [title not yet available] [FBrf0132177]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.: Berkeley Drosophila Genome Project. [FBrf0125078]

Automatic genome annotation

FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126705]