Gene Dmel\CG18476

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General Information

Symbol

Dmel\CG18476

Species

D. melanogaster

Name

CG18476

Annotation symbol

CG18476

Feature type

protein_coding_gene

FlyBase ID

FBgn0037931

Created / Updated

2003-12-01/2003-12-01

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

86E15-86E15

Sequence location

3R:7,500,631..7,503,835 [-]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol CG18476 (FBgn0037931). It has the cytological map location 86E15. Its sequence location is 3R:7500631..7503835. Its molecular function is described as: zinc ion binding; nucleic acid binding. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

86E15-86E15

Limits computationally determined from genome sequence between P{PZ}tho¹&P{PZ}l(3)04629⁰⁵²⁷⁵ and P{EP}Lk6^EP886

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\CG18476 for information on other features

Comments on Gene Model

DGC clone appears problematic (GH20378): incomplete CDS.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG18476-RA

FBtr0082443

NM_169419

2954

936

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG18476-PA

FBpp0081919

109.1

936

8.15

NP_731615

AAF54675

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

PANTHER - Protein classification by function, families, and pathways

•

FBgn0037931

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Zinc finger, C2H2-type (IPR007087)

Zinc finger, AD-type (IPR012934)

Zinc finger, C2H2-type/integrase, DNA-binding (IPR013087)

Zinc finger, C2H2-like (IPR015880)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Maps to

Does NOT map to

Identified with

(BDGP Project Members, 2000-)

IP01261

(Hoskins et al., 2005)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

DEDB - Drosophila exon database: splicing graphs

•

9064

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Microarray Data

Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002)

Untitled Document detailed view

AA820394
AI389251

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0037931

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0037931

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0037931

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of CG18476	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG18476	Class	Mutagen	Stocks	Known lesion
CG18476^GD1692		in vitro construct \| RNAi in vitro construct \| regulatory fusion	1	Yes

Aneuploid Aberrations

Useful deficiency

Df(3R)M-Kx1

Useful duplication

Dp(3;3)M86D⁺2

Disrupted in

Df(3R)Exel7309

(Ryder, 2004.4.26)

Df(3R)Exel8154

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD1692}

Insertions

Type of insertions

Name

Expression data

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 3 )

Molecular Function

CV term

Evidence

References

nucleic acid binding

inferred from electronic annotation with InterPro:IPR013087

(FlyBase Curators et al., 2004-)

zinc ion binding

inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR012934, InterPro:IPR015880

(FlyBase Curators et al., 2004-)

Biological Process

CV term

Evidence

References

Cellular Component

CV term

Evidence

References

nucleus

inferred from electronic annotation with InterPro:IPR012934

(FlyBase Curators et al., 2004-)

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG18476 allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

66531

Drosophila PIMRider - The Drosophila Protein Interaction map

•

522453

Orthologs

Genome-wide drosophilid orthologs

Dana\GF16627

Dere\GG17206

Dgri\GH19322

Dmoj\GI23545

Dper\GL12260

Dpse\GA14950

Dsec\GM26084

Dsim\GD20647

Dvir\GJ10292

Dwil\GK11228

Dyak\GE10099

Curated drosophilid orthologs

Dpse\GA14950

Linkouts

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 1 )

VDRC

v6527

w¹¹¹⁸; P{GD1692}v6527/TM3

Genomic Clones ( 1 )

BACR11G22

cDNA Clones ( 12 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

EK123734

RNAi & Array Information

Affy Oligo

Linkouts

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0037931

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0037931

Antibody Information

Other Information

Discoverer

Etymology

Identification

Position Effect Variegation Data

Relationship to Other Genes

Source for database identity of

Source for database merge of

Source for merge of: CG17822 CG18476

(Whitfield, 2000.5.4)

Additional comments

Release 1 annotation CG17822 corresponds to part of release 3.2 annotation CG18476.

(FlyBase, 1996-)

Comments About Role

Comments About Molecular Function

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_169419

RefSeq (Proteins)

•

NP_731615

DDBJ / EMBL / GenBank

•

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Zinc finger, C2H2-type (IPR007087)

Zinc finger, AD-type (IPR012934)

Zinc finger, C2H2-type/integrase, DNA-binding (IPR013087)

Zinc finger, C2H2-like (IPR015880)

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

66531

DEDB - Drosophila exon database: splicing graphs

•

9064

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0037931

Drosophila PIMRider - The Drosophila Protein Interaction map

•

522453

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0037931

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0037931

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0037931

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0037931

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0037931

PANTHER - Protein classification by function, families, and pathways

•

FBgn0037931

University of Chicago Dev. Expression

•

FBgn0037931

Synonyms & Secondary IDs ( 2 )

Reported As

Symbol Synonym

CG17822

CG18476

(Hoskins et al., 2005)

Name Synonym

CG18476

Secondary FlyBase IDs

FBgn0037932

References ( 11 )

Research paper

Hoskins et al., 2005, Nucleic Acids Res. 33(21): e185: Rapid and efficient cDNA library screening by self-ligation of inverse PCR products (SLIP). [FBrf0191341]

Supplementary material

Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]

Personal communication to FlyBase

Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]
Whitfield, 2000.5.4, FlyBase error report for CG17822 on Thu May 4 02:22:31 2000.: FlyBase error report for CG17822 on Thu May 4 02:22:31 2000. [FBrf0129030]

FlyBase analysis

FlyBase, 1996-, FlyBase inference based on genome sequence analysis.: FlyBase inference based on genome sequence analysis. [FBrf0104946]
FlyBase, 1992-, FlyBase curation: FlyBase curation. [FBrf0105495]

Computer file

BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.: Berkeley Drosophila Genome Project. [FBrf0125078]

Automatic genome annotation

FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126705]

Curated genome annotation

Li, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126682]