A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\Or85d

General Information
SymbolDmel\Or85dSpeciesD. melanogaster
NameOdorant receptor 85dAnnotation symbolCG11742
Feature typeprotein_coding_geneFlyBase IDFBgn0037594
Created / Updated2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)3RRecombination map
Cytogenetic map85A3-85A3Sequence location3R:4,378,330..4,379,690 [+]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
The gene Odorant receptor 85d is referred to in FlyBase by the symbol Or85d (CG11742, FBgn0037594). It has the cytological map location 85A3. Its sequence location is 3R:4378330..4379690. Its molecular function is described as: olfactory receptor activity; odorant binding. It is involved in the biological process sensory perception of smell. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
85A3-85A3  
Limits computationally determined from genome sequence between P{EP}EP833 and P{lacW}l(3)L4740L4740  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Please see the GBrowse view of Dmel\Or85d for information on other features
detailed view FBtr0081872 FBpp0081361 FBti0075522 FBti0042487
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
Or85d-RA
FBtr0081872
 NM_079557
  1239
  412
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
Or85d-PA  
FBpp0081361  
48.0  
412  
8.86  
  NP_524281
  AAF54249
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
•
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
Olfactory receptor, Drosophila (IPR004117)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AE003679
AAF54249
 
EL869673
 
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Lethality
        Allele
        viable
        Sterility
        Allele
        fertile
        Phenotype manifest in
        Allele
        hide Classical Alleles ( 2 )
        For All Classical Alleles Show

        Allele of Or85dClassMutagenStocksKnown lesion
        Or85dMB02185
          		1 --
          Or85df057362 --
          hide Alleles Carried on Transgenic Constructs ( 1 )
          For All Alleles Carried on Transgenic Constructs Show

          Allele of Or85dClassMutagenStocksKnown lesion
          Or85dGD6720 Yes
          hide Aneuploid Aberrations
          Useful deficiency
           
          Useful duplication
           
          Disrupted in
          (Ryder, 2004.4.26)
          hide Transgenic Constructs & Insertions
          Transgenic Constructs
          Type of construct
          Name
          Expression data
          UAS construct
          P{GD672}
          NA
          characterization construct
          P{Or85d-Mmus\Cd8a.GFP}
          NA
          Insertions
          Type of insertions
          Name
          Expression data
          miscellaneous insertions
          PBac{WH}Or85df05736
          NA
          insertion of enhancer trap binary system
          Mi{ET1}Or85dMB02185
          No
          hide Related Comments
          Please look at the allele reports for the complete phenotype data
          hide Gene Ontology: Function, Process & Cellular Component ( 5 )
          hide Molecular Function
          CV term
          Evidence
          References
          odorant binding
          inferred from electronic annotation with InterPro:IPR004117
          (FlyBase Curators et al., 2004-)
          olfactory receptor activity
          inferred from sequence or structural similarity
          (Swiss-Prot Project Members, 2000.5.1)
          inferred from electronic annotation with InterPro:IPR004117
          (FlyBase Curators et al., 2004-)
          hide Biological Process
          CV term
          Evidence
          References
          sensory perception of smell
          inferred from sequence or structural similarity
          (Swiss-Prot Project Members, 2000.5.1)
          inferred from electronic annotation with InterPro:IPR004117
          (FlyBase Curators et al., 2004-)
          hide Cellular Component
          CV term
          Evidence
          References
          integral to membrane
          inferred from sequence or structural similarity
          (Swiss-Prot Project Members, 2000.5.1)
          membrane
          inferred from electronic annotation with InterPro:IPR004117
          (FlyBase Curators et al., 2004-)
          hide Sequence Ontology: Class of Gene
          protein_coding_gene
           
          nuclear_gene
           
          hide Interactions & Pathways
          hide Summary of Genetic Interactions
          Interacts with
          Please look at the allele data for full details of the genetic interactions
          Or85d allele
          Gene
          References
          hide External Data
          Linkouts
          BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
          •
          hide Orthologs
          Genome-wide drosophilid orthologs
          Curated drosophilid orthologs
           
          Linkouts
          hide Functional Complementation between Species
          hide Inter-Species Misexpression Data
          Produces phenotype in
          Produces NO phenotype in
          hide Stocks & Reagents
          hide Stocks Listed in FlyBase ( 3 )
          Harvard
          -
          PBac{WH}Or85df05736
          Bloomington
          18902
          w1118; PBac{WH}Or85df05736
          23471
          w1118; Mi{ET1}Or85dMB02185
          hide Genomic Clones ( 2 )
          hide cDNA Clones ( 1 )
          Please Note
          This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
          cDNA Clones, Fully Sequenced
          BDGP DGC clones
          Other clones
          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
          Other clones
          hide RNAi & Array Information
          Affy Oligo
          Linkouts
          DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
          •
          GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
          •
          hide Antibody Information
          hide Other Information
          hide Discoverer
          hide Etymology
          hide Identification
          hide Position Effect Variegation Data
          hide Relationship to Other Genes
          Source for database identity of
          Source for identity of: Or85d CG11742
          (Warr and Vosshall, 2000.5.19)
          Source for database merge of
          Additional comments
          hide Comments About Role
          hide Comments About Molecular Function
          hide Other Comments
          hide External Crossreferences & Linkouts
          Sequence Crossreferences
          RefSeq (Transcripts)
          •
          RefSeq (Proteins)
          •
          DDBJ / EMBL / GenBank
          •
          UniProtKB/Swiss-Prot
          •
          Other Crossreferences
          InterPro domains - A database of protein families, domains, and functional sites
          •
          Olfactory receptor, Drosophila (IPR004117)
          Linkouts
          BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
          •
          DEDB - Drosophila exon database: splicing graphs
          •
          DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
          •
          FLIGHT - Cell culture data for RNAi and other high-throughput technologies
          •
          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
          •
          FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
          •
          GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
          •
          GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
          •
          PANTHER - Protein classification by function, families, and pathways
          •
          hide Synonyms & Secondary IDs ( 7 )
          Reported As
          Symbol Synonym
          85.2
          (Warr and Vosshall, 2000.5.19)
          85A.2
          (Warr and Vosshall, 2000.5.19)
          85d
          (Vogt et al., 2002)
          CG11742
           
          DOR114
          (Warr and Vosshall, 2000.5.19)
          Or85d
          (de Bruyne and Warr, 2006, Goldman et al., 2005)
          Name Synonym
          Odorant receptor 85d
           
          Secondary FlyBase IDs
            hide References ( 19 )
            Research paper
            Couto et al., 2005, Curr. Biol. 15(17): 1535--1547
            Molecular, anatomical, and functional organization of the Drosophila olfactory system. [FBrf0187305]
            Goldman et al., 2005, Neuron 45(5): 661--666
            Coexpression of two functional odor receptors in one neuron. [FBrf0184216]
            Heeger et al., 2005, Genes Dev. 19(17): 2041--2053
            Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog. [FBrf0187592]
            Robertson et al., 2003, Proc. Natl. Acad. Sci. USA 100(Supplement 2): 14537--14542
            Molecular evolution of the insect chemoreceptor gene superfamily in Drosophila melanogaster. [FBrf0168007]
            Vogt et al., 2002, J. exp. Biol. 205(6): 719--744
            A comparative study of odorant binding protein genes: differential expression of the PBP1-GOBP2 gene cluster in Manduca sexta (Lepidoptera) and the organization of OBP genes in Drosophila melanogaster (Diptera). [FBrf0147124]
            Vosshall et al., 2000, Cell 102(2): 147--159
            An olfactory sensory map in the fly brain. [FBrf0130146]
            Supplementary material
            Dietzl et al., 2007, Nature 448(7150):
            Supplementary Table 1. [FBrf0202579]
            Review
            de Bruyne and Warr, 2006, BioEssays 28(1): 23--34
            Molecular and cellular organization of insect chemosensory neurons. [FBrf0189797]
            Otaki and Yamamoto, 2003, J. Theor. Biol. 223(1): 27--37
            Length analyses of Drosophila odorant receptors. [FBrf0160830]
            Personal communication to FlyBase
            Bellen, 2007.4.5, batch731.xml
            batch731.xml [FBrf0191801]
            Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase.
            Exelixis insertion alleles that are not in FlyBase. [FBrf0179797]
            FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.
            Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
            Ryder, 2004.4.26, Exelixis CG deletion data.
            Exelixis CG deletion data. [FBrf0184335]
            Warr and Vosshall, 2000.5.19, Odorant receptors.
            Odorant receptors. [FBrf0128191]
            FlyBase analysis
            FlyBase, 1992-, FlyBase curation
            FlyBase curation. [FBrf0105495]
            Protein sequence record
            Swiss-Prot Project Members, 2000.5.1, UniProtKB: Q9VHQ2
            PUTATIVE ODORANT RECEPTOR 85D. [FBrf0132016]
            Automatic genome annotation
            FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.]
            [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
            Curated genome annotation
            Vosshall, 1999.11, [Annotations performed at the Celera Jamboreee.]
            [Annotations performed at the Celera Jamboreee.] [FBrf0126694]
            Letter
            Warr et al., 2000, Cell 102(2): 145--146
            A unified nomenclature system for the Drosophila odorant receptors. [FBrf0130157]