A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\CG10743

General Information
SymbolDmel\CG10743SpeciesD. melanogaster
NameCG10743Annotation symbolCG10743
Feature typeprotein_coding_geneFlyBase IDFBgn0036376
Created / Updated2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)3LRecombination map
Cytogenetic map70B4-70B4Sequence location3L:13,506,354..13,509,376 [+]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
This gene is referred to in FlyBase by the symbol CG10743 (FBgn0036376). It has the cytological map location 70B4. Its sequence location is 3L:13506354..13509376. Its molecular function is described as: receptor signaling protein tyrosine kinase signaling protein activity; transporter activity. It is involved in the biological process transport. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.

hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
70B4-70B4  
Limits computationally determined from genome sequence between P{lacW}l(3)L5212L5212&P{PZ}l(3)0587105871 and P{EP}EP3561EP3561  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Please see the GBrowse view of Dmel\CG10743 for information on other features
detailed view FBtr0075818 FBtr0075813 FBtr0075814 FBtr0075817 FBpp0075560 FBpp0075556 FBpp0075555 FBpp0075559 FBti0044943 FBti0009942 FBti0030119 FBti0076110
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
CG10743-RA
FBtr0075814
 NM_140404
  2792
  680
CG10743-RB
FBtr0075813
 NM_168556
  2813
  680
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
CG10743-PA  
FBpp0075556  
75.6  
680  
7.86  
  NP_648661
  AAF49801
CG10743-PB  
FBpp0075555  
75.6  
680  
7.86  
  NP_729920
  AAN11829
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
•
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
Major intrinsic protein (IPR000425)
Sterile alpha motif SAM (IPR001660)
Sterile alpha motif homology (IPR010993)
Sterile alpha motif homology 2 (IPR011510)
Sterile alpha motif-type (IPR013761)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AA201927
 
AA246321
 
AA246507
 
AA391362
 
AA391469
 
AA438951
 
AA440017
 
AA440899
 
AA538896
 
AA539664
 
AA540121
 
AA816910
 
AA817544
 
AA820254
 
AA820481
 
AA941837
 
AA950144
 
AA950655
 
AA951058
 
AA951811
 
AA990799
 
AE003537
AAF49801
 
AE003537
AAN11829
 
AI511686
 
AI514351
 
AI514386
 
AI514698
 
AI515239
 
AI519689
 
AI519901
 
AI519942
 
AI520168
 
BF490011
 
BF496730
 
BG635067
 
BI163638
 
BI169491
 
BI231009
 
BI235228
 
BI236019
 
BI236513
 
BI242928
 
BI243313
 
BI357082
 
BI357730
 
BI358303
 
BI361593
 
BI363602
 
BI368672
 
BI374431
 
BI486640
 
BI637284
 
BP549161
 
BP549162
 
BT010308
AAQ23626
 
CK086490
 
CO196630
 
EC056883
 
EC202181
 
EC247331
 
EC251174
 
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    (BDGP Project Members, 2000-)
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide Microarray Data
        Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002)
        Untitled Document detailed view FBtr0075818 FBtr0075813 FBtr0075814 FBtr0075817
        AA951811
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Phenotype manifest in
        Allele
        hide Classical Alleles ( 1 )
        For All Classical Alleles Show

        Allele of CG10743ClassMutagenStocksKnown lesion
        CG10743EY229991 --
        hide Alleles Carried on Transgenic Constructs ( 1 )
        For All Alleles Carried on Transgenic Constructs Show

        Allele of CG10743ClassMutagenStocksKnown lesion
        CG10743GD59022 Yes
        hide Aneuploid Aberrations
        Useful deficiency
         
        Useful duplication
         
        Disrupted in
        (Ryder, 2004.4.26)
        hide Transgenic Constructs & Insertions
        Transgenic Constructs
        Type of construct
        Name
        Expression data
        UAS construct
        P{GD5902}
        NA
        Insertions
        Type of insertions
        Name
        Expression data
        insertion of mobile activating element
        P{EPgy2}CG10743EY22999
        NA
        hide Related Comments
        Please look at the allele reports for the complete phenotype data
        hide Gene Ontology: Function, Process & Cellular Component ( 4 )
        hide Molecular Function
        CV term
        Evidence
        References
        receptor signaling protein tyrosine kinase signaling protein activity
        inferred from sequence or structural similarity with EMBL:AF034803
        (FlyBase, 1992-)
        transporter activity
        inferred from electronic annotation with InterPro:IPR000425
        (FlyBase Curators et al., 2004-)
        hide Biological Process
        CV term
        Evidence
        References
        transport
        inferred from electronic annotation with InterPro:IPR000425
        (FlyBase Curators et al., 2004-)
        hide Cellular Component
        CV term
        Evidence
        References
        membrane
        inferred from electronic annotation with InterPro:IPR000425
        (FlyBase Curators et al., 2004-)
        hide Sequence Ontology: Class of Gene
        protein_coding_gene
         
        nuclear_gene
         
        hide Interactions & Pathways
        hide Summary of Genetic Interactions
        Interacts with
        Please look at the allele data for full details of the genetic interactions
        CG10743 allele
        Gene
        References
        hide External Data
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        hide Orthologs
        Genome-wide drosophilid orthologs
        Curated drosophilid orthologs
         
        Linkouts
        InParanoid orthologs - Eukaryotic orthologs
        •
        hide Functional Complementation between Species
        hide Inter-Species Misexpression Data
        Produces phenotype in
        Produces NO phenotype in
        hide Stocks & Reagents
        hide Stocks Listed in FlyBase ( 3 )
        VDRC
        v16850
        w1118; P{GD5902}v16850
        v16851
        w1118; P{GD5902}v16851
        Bloomington
        22658
        y1 w67c23; P{EPgy2}CG10743EY22999
        hide Genomic Clones ( 2 )
        hide cDNA Clones ( 52 )
        Please Note
        This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
        cDNA Clones, Fully Sequenced
        BDGP DGC clones
        Other clones
        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        hide RNAi & Array Information
        Affy Oligo
        Linkouts
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        hide Antibody Information
        hide Other Information
        hide Discoverer
        hide Etymology
        hide Identification
        hide Position Effect Variegation Data
        hide Relationship to Other Genes
        Source for database identity of
        Source for database merge of
        Additional comments
        FlyBase curator comment: Correspondence with author Astigarraga revealed that 'Liprin-β' = 'CG10743'.
        (Astigarraga et al., 2008)
        hide Comments About Role
        hide Comments About Molecular Function
        hide Other Comments
        hide External Crossreferences & Linkouts
        Sequence Crossreferences
        RefSeq (Transcripts)
        •
        RefSeq (Proteins)
        •
        DDBJ / EMBL / GenBank
        •
        UniProtKB/TrEMBL
        •
        Other Crossreferences
        InterPro domains - A database of protein families, domains, and functional sites
        •
        Major intrinsic protein (IPR000425)
        Sterile alpha motif SAM (IPR001660)
        Sterile alpha motif homology (IPR010993)
        Sterile alpha motif homology 2 (IPR011510)
        Sterile alpha motif-type (IPR013761)
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        DEDB - Drosophila exon database: splicing graphs
        •
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        InParanoid orthologs - Eukaryotic orthologs
        •
        PANTHER - Protein classification by function, families, and pathways
        •
        hide Synonyms & Secondary IDs ( 2 )
        Reported As
        Symbol Synonym
        CG10743
         
        Liprin-β
        (Astigarraga et al., 2008)
        Name Synonym
        CG10743
         
        Secondary FlyBase IDs
          hide References ( 10 )
          Supplementary material
          Giot et al., 2003, Science 302(5651):
          Tables S1 to S7. [FBrf0166452]
          Personal communication to FlyBase
          Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center
          RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
          Bellen, 2006.8.3, MBBatch686_2.xml
          MBBatch686_2.xml [FBrf0191805]
          FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.
          Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
          Ryder, 2004.4.26, Exelixis CG deletion data.
          Exelixis CG deletion data. [FBrf0184335]
          Abstract
          Astigarraga et al., 2008, A. Dros. Res. Conf. 49: 548B
          Role of the Liprin family of proteins in axon targeting and synapse formation. [FBrf0203737]
          FlyBase analysis
          FlyBase, 1992-, FlyBase curation
          FlyBase curation. [FBrf0105495]
          Computer file
          BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.
          Berkeley Drosophila Genome Project. [FBrf0125078]
          Automatic genome annotation
          FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.]
          [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
          Curated genome annotation
          Zhao, 1999.11, [Annotations performed at the Celera Jamboreee.]
          [Annotations performed at the Celera Jamboreee.] [FBrf0126701]