Gene Dmel\snky

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\snky for information on other features

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

snky-RA

FBtr0075827

NM_140376

2145

714

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

snky-PA

FBpp0075569

83.0

714

9.23

NP_648633

AAF49838

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Zinc finger, RING-type (IPR001841)

DC-STAMP-like (IPR012858)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VU52

Maps to

Does NOT map to

Identified with

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

External Data & Images

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

lethal | paternal effect | recessive

Sterility

Allele

male sterile

snky¹

male sterile (with Df(3L)Syx13-01470R5)

snky¹

male sterile | recessive

female fertile

snky¹

Phenotype manifest in

Allele

male pronucleus

snky¹

plasma membrane & spermatozoon

snky¹

Classical Alleles ( 4 )

For All Classical Alleles Show

Allele of snky	Mutagen	Known lesion
snky¹		--
snky²	ethyl nitrosourea	--
snky^Z0566	ethyl methanesulfonate	Yes
snky^Z4482	ethyl methanesulfonate	Yes

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of snky	Mutagen	Stocks	Known lesion
snky^+t7.3	in vitro construct \| genomic fragment	0	Yes
snky^GD2451	in vitro construct \| RNAi in vitro construct \| regulatory fusion	2	Yes
snky^{T:Avic\GFP-EGFP}	in vitro construct \| site directed mutagenesis	0	Yes

Aneuploid Aberrations

Useful duplication

Dp(3;3)M71

Useful deficiency

Df(3L)VW1

Disrupted in

Df(3L)Exel6261

(Ryder, 2004.4.26)

Df(3L)Syx13-01470R5

In(3LR)C190^LUbx^42TR

(FlyBase Curators et al., 2004-)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD2451}

characterization construct

P{snky.EGFP}

P{snky^+t7.3}

Insertions

Type of insertions

Name

Expression data

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 8 )

Molecular Function

CV term

Evidence

References

protein binding

inferred from electronic annotation with InterPro:IPR001841

zinc ion binding

inferred from electronic annotation with InterPro:IPR001841

(FlyBase Curators et al., 2004-)

Biological Process

CV term

Evidence

References

fertilization, exchange of chromosomal proteins

inferred from mutant phenotype

sperm chromatin decondensation

single fertilization

non-traceable author statement

(Fitch et al., 1999)

inferred from mutant phenotype

sperm plasma membrane disassembly

inferred from mutant phenotype

inferred from mutant phenotype

Cellular Component

CV term

Evidence

References

acrosome

inferred from direct assay

(FlyBase Curators et al., 2004-)

inferred from direct assay

(Wilson et al., 2004)

integral to membrane

inferred from electronic annotation with InterPro:IPR012858

Sequence Ontology: Class of Gene

gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

snky allele

Gene

References

External Data

Orthologs

Genome-wide drosophilid orthologs

Curated drosophilid orthologs

Dpse\GA10888

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 2 )

VDRC

v5246

w¹¹¹⁸; P{GD2451}v5246

v5247

w¹¹¹⁸; P{GD2451}v5247

Genomic Clones ( 1 )

BACR13C22

cDNA Clones ( 3 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Affy Oligo

Antibody Information

Other Information

Discoverer

Etymology

Identification

Position Effect Variegation Data

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Source for merge of: snky CG11281

Comments About Role

snky is required for the initial response of the sperm to cytoplasmic cues in the egg and for the subsequent initiation of embryogenesis.