Gene Dmel\CG33523

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General Information

Symbol

Dmel\CG33523

Species

D. melanogaster

Name

CG33523

Annotation symbol

CG33523

Feature type

protein_coding_gene

FlyBase ID

FBgn0053523

Created / Updated

2004-11-23/2004-11-23

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

64F5-65A1

Sequence location

3L:5,917,155..5,923,228 [+]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol CG33523 (FBgn0053523). It has the cytological map location 64F5-65A1. Its sequence location is 3L:5917155..5923228. Its molecular function is described as structural molecule activity. The biological processes in which it is involved are not known. 10 alleles are reported. The phenotype of these alleles is annotated with anterior fascicle. It has 4 annotated transcripts and 4 annotated polypeptides.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

64F5-65A1

Limits computationally determined from genome sequence between P{PZ}vn¹⁰⁵⁶⁷ and P{PZ}loj⁰⁴⁰²⁶

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\CG33523 for information on other features

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG33523-RA

FBtr0091478

NM_001014566

1508

234

CG33523-RB

FBtr0091476

NM_001014568

1360

206

CG33523-RC

FBtr0091477

NM_001014567

1664

240

CG33523-RD

FBtr0091475

NM_001014569

2383

498

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG33523-PA

FBpp0090957

25.8

234

9.29

NP_001014566

AAF50728

CG33523-PB

FBpp0090955

22.7

206

9.30

NP_001014568

AAN12234

CG33523-PC

FBpp0090956

26.4

240

9.06

NP_001014567

AAN12233

CG33523-PD

FBpp0090954

56.4

498

7.74

NP_001014569

AAN12232

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Major sperm protein (IPR000535)

Cellular retinaldehyde-binding/triple function, C-terminal (IPR001251)

PapD-like (IPR008962)

Vesicle-associated membrane protein (IPR016763)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Maps to

Does NOT map to

Identified with

(BDGP Project Members, 2000-)

(Oliver, 2001.8.16)

GH09028

(BDGP Project Members, 2000-, Oliver, 2001.8.16)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

DEDB - Drosophila exon database: splicing graphs

•

5093

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Microarray Data

Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002)

Untitled Document detailed view

AA941761

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0053523

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

Other Phenotypes

Allele

neuroanatomy defective | larval stage, with Scer\GAL4^elav-C155

CG33523^EP3539

Sterility

Allele

fertile

Phenotype manifest in

Allele

anterior fascicle & synapse, with Scer\GAL4^elav-C155

CG33523^EP3539

anterior fascicle, with Scer\GAL4^elav-C155

CG33523^EP3539

Classical Alleles ( 8 )

For All Classical Alleles Show

Allele of CG33523	Mutagen	Stocks	Known lesion
CG33523^EP3539	P-element activity	1	Yes
CG33523^EP3647	P-element activity	1	--
CG33523^EP3648	P-element activity	1	--
CG33523^EY01207		1	--
CG33523^c03097	piggyBac transposase	1	--
CG33523^c04974	piggyBac transposase	1	--
CG33523^c05404	piggyBac transposase	1	--
CG33523^e03176	piggyBac transposase	2	--

Alleles Carried on Transgenic Constructs ( 2 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG33523	Class	Mutagen	Stocks	Known lesion
CG33523^GD10886		in vitro construct \| RNAi in vitro construct \| regulatory fusion	0	Yes
CG33523^GD2326		in vitro construct \| RNAi in vitro construct \| regulatory fusion	3	Yes

Aneuploid Aberrations

Useful deficiency

Df(3L)XAS96

Useful duplication

Dp(3;3)M34

Disrupted in

Df(3L)Exel7210

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD10886}

P{GD2326}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

PBac{PB}CG33523^c03097

PBac{PB}CG33523^c04974

PBac{PB}CG33523^c05404

PBac{RB}CG33523^e03176

insertion of mobile activating element

P{EPgy2}CG33523^EY01207

P{EP}CG33523^EP3539

P{EP}CG33523^EP3647

P{EP}CG33523^EP3648

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 3 )

Molecular Function

CV term

Evidence

References

structural molecule activity

inferred from electronic annotation with InterPro:IPR000535

(FlyBase Curators et al., 2004-)

Biological Process

CV term

Evidence

References

biological_process

no biological data available

(FlyBase Curators, 2002-)

Cellular Component

CV term

Evidence

References

cellular_component

no biological data available

(FlyBase Curators, 2002-)

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG33523 allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

64128

Orthologs

Genome-wide drosophilid orthologs

Dana\GF24005

Dere\GG15302

Dgri\GH14689

Dmoj\GI13304

Dper\GL21079

Dpse\GA28323

Dsec\GM14735

Dvir\GJ12072

Dwil\GK16664

Dyak\GE21523

Curated drosophilid orthologs

Linkouts

InParanoid orthologs - Eukaryotic orthologs

•

ENSANGP00000029204
Anopheles gambiae (Ensembl)
ENSBTAP00000015423
Bos taurus (Ensembl)
ENSCAFP00000017492
Canis familiaris (Ensembl)
ENSCINP00000010917
Ciona intestinalis (Ensembl)
NEWSINFRUP00000144789
Takifugu rubripes (Ensembl)
ENSGALP00000026692
Gallus gallus (Ensembl)
ENSP00000252430
Homo sapiens (Ensembl)
ENSMMUP00000023459
Macaca mulatta (Ensembl)
ENSMODP00000021552
Monodelphis domestica (Ensembl)
ENSPTRP00000037145
Pan troglodytes (Ensembl)
ENSRNOP00000004533
Rattus norvegicus (Ensembl)
GSTENP00026062001
Tetraodon nigroviridis (Ensembl)
ENSXETP00000021985
Xenopus tropicalis (Ensembl)
WBGene00030678
Caenorhabditis briggsae (Wormbase)
WBGene00015148
Caenorhabditis elegans (Wormbase)
ZDB-CDNA-041114-1
Danio rerio (Zfin)
ZDB-GENE-041114-1
Danio rerio (Zfin)
MGI:1924013
Mus musculus (Informatics)
SPAC589.09
Schizosaccharomyces pombe (Sanger)

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 12 )

PBac{PB}CG33523^c03097

PBac{PB}CG33523^c04974

PBac{PB}CG33523^c05404

PBac{RB}CG33523^e03176

VDRC

v37237

w¹¹¹⁸; P{GD2326}v37237

v37238

w¹¹¹⁸; P{GD2326}v37238

v44377

w¹¹¹⁸; P{GD2326}v44377

Bloomington

18128

w¹¹¹⁸; PBac{RB}CG33523^e03176

15331

y¹ w^67c23; P{EPgy2}CG33523^EY01207

Genomic Clones ( 2 )

cDNA Clones ( 36 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones