• Home
• Tools
  • BLAST
  • GBrowse
  • QueryBuilder
  • TermLink
  • ImageBrowse
  • Interactions Browser
  • Apollo
  • CytoSearch
  • QuickSearch
  • Batch Download
  • Coordinate Converter
  • Google™ FlyBase
  • Find A Person
  • Update An Address
  • Add A New Person
• Files
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases FTP
  • Genomes FTP
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Synteny Table
  • Drosophilidae
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All resources
  • Interactive Fly
  • Textpresso for Fly
  • AAA site
  • BDGP
  • DHGP
  • DGRC
  • Model Organisms
  • Stock Collections:
  • Bloomington
  • DrosDel
  • Ehime
  • Exelixis (Harvard)
  • GDP (Baylor)
  • Kyoto
  • NIG-Fly
  • Szeged
  • Tucson
  • VDRC
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Known Problems
  • Contact FlyBase
• Archives
  • Prior Home Page
  • R4.3 BLAST
  • R4.3 GBrowse
  • Older Archives

Gene Dmel\CG8979

General Information
Symbol	Dmel\CG8979	Species	D. melanogaster
Name	CG8979	Annotation symbol	CG8979
Feature type	protein_coding_gene	FlyBase ID	FBgn0033669
Created / Updated	2003-12-02/2003-12-02
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	48D5-48D5	Sequence location	2R:7,854,841..7,856,348 [-]
Map ( GBrowse )	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol CG8979 (FBgn0033669). It has the cytological map location 48D5. Its sequence location is 2R:7854841..7856348. Its molecular function is described as proteasome inhibitor activity. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 48D5-48D5   Limits computationally determined from genome sequence between P{lacW}l(2)k06612k06612 and P{lacW}jebk05644
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology) References Gene Order (overall orientation not stated) References
Gene Model & Products
Please see the GBrowse view of Dmel\CG8979 for information on other features
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG8979-RA FBtr0088051  NM_136871   1132   270 CG8979-RB FBtr0088053  NM_165854   1120   270 CG8979-RC FBtr0088052  NM_165855   1179   270
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kD) Length (aa) Theoretical pI RefSeq ID GenBank protein CG8979-PA   FBpp0087157   30.1   270   5.18     NP_610715   AAF58602 CG8979-PB   FBpp0087159   30.1   270   5.18     NP_725092   AAM68701 CG8979-PC   FBpp0087158   30.1   270   5.18     NP_725093   AAM68702
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts	PANTHER - Protein classification by function, families, and pathways • FBgn0033669
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE003824 AAF58602   AE003824 AAM68701   AE003824 AAM68702   AI062169   AI062170   AI109860   AI259892   AI513094   AI517243   AI546699   AI944752   AI946119   AI947037   AY058250 AAL13479   BE975188   BF486743   BF498952   BF501235   BF502978   BI361966   BI369246   BI578231   BI578312   BI580534   BI637369   BI640943   BP551295   BP551296   CA805953   CA806901   CO292763   CO304062   EC064800   EC227070   EC247043
UniProtKB/Swiss-Prot	Q9V637
UniProtKB/TrEMBL
Maps to
Does NOT map to
Identified with	bs21b04 bs05b01 bs34c12 LP03412 SD10439 (Oliver, 2001.8.16) GH01278 (BDGP Project Members, 2000-, Oliver, 2001.8.16)
Mapped Features & Mutations
Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here Type Symbol & Location Additional Notes References
External Data
Linkouts	DEDB - Drosophila exon database: splicing graphs • 12883
Crossreferences
Expression Data
FlyBase-Curated Data
Transcript and Protein data	Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
Summary of Transcript Expression
Stage Tissue/Position Reference
Marker for
Subcellular Localization
CV Term
Summary of Polypeptide Expression
Stage Tissue/Position Reference
Marker for
Subcellular Localization
CV Term
Microarray Data
	Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002) AI062170
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033669 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • FBgn0033669 GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies • FBgn0033669 BDGP expression data • Show all BDGP original images, annotations and embryonic microarray data for CG8979 FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG8979 Stage(s) 1-3 Stage(s) 4-6 Stage(s) 7-8 Stage(s) 9-10 Stage(s) 11-12 Stage(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG8979 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG8979 Class Mutagen Stocks Known lesion CG8979GD13764 in vitro construct | RNAi in vitro construct | regulatory fusion 2 Yes
Aneuploid Aberrations
Useful duplication	Dp(2;2)Y3b
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13764} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{SUPor-P}KG03360 NA
Related Comments
	Please look at the allele reports for the complete phenotype data
Gene Ontology: Function, Process & Cellular Component ( 1 )
Molecular Function
CV term Evidence References
proteasome inhibitor activity inferred from sequence or structural similarity with EMBL:D88378; protein_id:BAA13603 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 2001.8.20)
Biological Process
CV term Evidence References
Cellular Component
CV term Evidence References
Sequence Ontology: Class of Gene
	protein_coding_gene   nuclear_gene
Interactions & Pathways
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG8979 allele Gene References
External Data
Linkouts	BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions • 62061
Orthologs
Genome-wide drosophilid orthologs	Dana\GF11798 Dere\GG22619 Dgri\GH20402 Dmoj\GI19589 Dper\GL10241 Dpse\GA21450 Dsec\GM20399 Dsim\GD25873 Dvir\GJ18358 Dwil\GK22249 Dyak\GE13488
Curated drosophilid orthologs	Dpse\GA21450
Linkouts	InParanoid orthologs - Eukaryotic orthologs • ENSANGP00000019186 Anopheles gambiae (Ensembl) ENSBTAP00000024505 Bos taurus (Ensembl) ENSCAFP00000010190 Canis familiaris (Ensembl) ENSGALP00000000338 Gallus gallus (Ensembl) ENSP00000327704 Homo sapiens (Ensembl) ENSMMUP00000006258 Macaca mulatta (Ensembl) ENSMODP00000024375 Monodelphis domestica (Ensembl) ENSPTRP00000022517 Pan troglodytes (Ensembl) ENSRNOP00000038926 Rattus norvegicus (Ensembl) DDB0232963 Dictyostelium discoideum (Dictybase) MGI:1346072 Mus musculus (Informatics)
Functional Complementation between Species
Inter-Species Misexpression Data
Produces phenotype in
Produces NO phenotype in
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v28858 w1118; P{GD13764}v28858 v28860 w1118; P{GD13764}v28860/TM3
Bloomington	14089 y1 w67c23; P{SUPor-P}KG03360
Genomic Clones ( 1 )
	BACR14L19
cDNA Clones ( 25 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH01278
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE55368 AT21258 SD23981 GH01277 RE72165 SD10439 GH09242 AT16506 RE74742 RE46408 AT18854 SD19363 RE72074 LP03412 GH27918 AT13441
Other clones	ESG015c.B21_B07 bs34c12 EK200920 ESG0120b.B21_H06 EK243543 bs05b01 bs21b04 bs39f02
RNAi & Array Information
Affy Oligo
Linkouts	DRSC - RNAi screening (Harvard): high-throughput cell culture data and design • FBgn0033669 GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data • FBgn0033669
Antibody Information
Other Information
Discoverer
Etymology
Identification
Position Effect Variegation Data
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Comments About Role
Comments About Molecular Function
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136871 NM_165855 NM_165854 RefSeq (Proteins) • NP_610715 NP_725093 NP_725092 DDBJ / EMBL / GenBank • AE003824 AAF58602 AAM68701 AAM68702 AI062170 AI259892 AI513094 AI546699 AI944752 AI946119 AI947037 AY058250 AAL13479 UniProtKB/Swiss-Prot • Q9V637
Other Crossreferences
Linkouts
	BDGP expression data • Show all BDGP original images, annotations and embryonic microarray data for CG8979 BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions • 62061 DEDB - Drosophila exon database: splicing graphs • 12883 DRSC - RNAi screening (Harvard): high-throughput cell culture data and design • FBgn0033669 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0033669 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • FBgn0033669 FlyExpress - Embryonic expression images (BDGP data) • FBgn0033669 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0033669 GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies • FBgn0033669 GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data • FBgn0033669 InParanoid orthologs - Eukaryotic orthologs • ENSANGP00000019186 Anopheles gambiae (Ensembl) ENSBTAP00000024505 Bos taurus (Ensembl) ENSCAFP00000010190 Canis familiaris (Ensembl) ENSGALP00000000338 Gallus gallus (Ensembl) ENSP00000327704 Homo sapiens (Ensembl) ENSMMUP00000006258 Macaca mulatta (Ensembl) ENSMODP00000024375 Monodelphis domestica (Ensembl) ENSPTRP00000022517 Pan troglodytes (Ensembl) ENSRNOP00000038926 Rattus norvegicus (Ensembl) DDB0232963 Dictyostelium discoideum (Dictybase) MGI:1346072 Mus musculus (Informatics) PANTHER - Protein classification by function, families, and pathways • FBgn0033669 University of Chicago Dev. Expression • FBgn0033669
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	cg8979 (Herold et al., 2003) CG8979
Name Synonym	CG8979
Secondary FlyBase IDs
References ( 9 )
Research paper	Herold et al., 2003, EMBO J. 22(10): 2472--2483 Genome-wide analysis of nuclear mRNA export pathways in Drosophila. [FBrf0158900]
Supplementary material	Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Protein sequence record	Swiss-Prot Project Members, 2001.8.20, UniProtKB: Q9V637 Putative proteasome inhibitor. [FBrf0151077]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Curated genome annotation	Anonymous, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126650]