Gene Dmel\CG1600

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General Information

Symbol

Dmel\CG1600

Species

D. melanogaster

Name

CG1600

Annotation symbol

CG1600

Feature type

protein_coding_gene

FlyBase ID

FBgn0033188

Created / Updated

2003-12-02/2003-12-02

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

43D2-43D3

Sequence location

2R:3,413,623..3,420,487 [-]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol CG1600 (FBgn0033188). It has the cytological map location 43D2-43D3. Its sequence location is 2R:3413623..3420487. Its molecular function is described as: zinc ion binding; oxidoreductase activity. It is involved in the biological process metabolic process. 5 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

43D2-43D3

Limits computationally determined from genome sequence between P{lacW}cos^k16101 and P{EP}CG1600^EP398

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\CG1600 for information on other features

Comments on Gene Model

EST data support existence of multiple transcripts

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG1600-RA

FBtr0088956

NM_165538

2022

381

CG1600-RB

FBtr0088958

NM_165539

1863

381

CG1600-RC

FBtr0088957

NM_136449

2050

434

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG1600-PA

FBpp0088030

41.4

381

5.94

NP_724572

AAF59235

CG1600-PB

FBpp0088032

41.4

381

5.94

NP_724573

AAF59234

CG1600-PC

FBpp0088031

47.0

434

6.05

NP_610293

AAM71096

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

PANTHER - Protein classification by function, families, and pathways

•

FBgn0033188

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Alcohol dehydrogenase superfamily, zinc-containing (IPR002085)

GroES-like (IPR011032)

Alcohol dehydrogenase GroES-like (IPR013154)

NAD(P)-binding (IPR016040)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Maps to

Does NOT map to

Identified with

GH18014

(BDGP Project Members, 2000-)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

DEDB - Drosophila exon database: splicing graphs

•

13502

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Microarray Data

Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002)

Untitled Document detailed view

AI387473
AI405728

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0033188

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0033188

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0033188

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

CG1600^CB03410

Phenotype manifest in

Allele

Classical Alleles ( 4 )

For All Classical Alleles Show

Allele of CG1600	Mutagen	Stocks	Known lesion
CG1600^CB03410	P-element activity	0	Yes
CG1600^EP2327	P-element activity	1	--
CG1600^EP398	P-element activity	2	--
CG1600^KG03987	P-element activity	1	--

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG1600	Class	Mutagen	Stocks	Known lesion
CG1600^GD9158		in vitro construct \| RNAi in vitro construct \| regulatory fusion	2	Yes

Aneuploid Aberrations

Useful deficiency

Df(2R)tor-rx6

Disrupted in

Df(2R)Exel6052

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD9158}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

P{PTT-GB}CG1600^CB03410

P{SUPor-P}CG1600^KG03987

insertion of enhancer trap

P{lacW}l(2)SH1499^SH1499

insertion of mobile activating element

P{EP}CG1600^EP2327

P{EP}CG1600^EP398

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 3 )

Molecular Function

CV term

Evidence

References

oxidoreductase activity

inferred from electronic annotation with InterPro:IPR002085, InterPro:IPR013154

(FlyBase Curators et al., 2004-)

zinc ion binding

inferred from electronic annotation with InterPro:IPR002085

(FlyBase Curators et al., 2004-)

Biological Process

CV term

Evidence

References

metabolic process

inferred from electronic annotation with InterPro:IPR016040

(FlyBase Curators et al., 2004-)

Cellular Component

CV term

Evidence

References

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG1600 allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

61563

Orthologs

Genome-wide drosophilid orthologs

Dana\GF11713

Dere\GG10734

Dgri\GH19809

Dmoj\GI19095

Dper\GL20107

Dpse\GA14040

Dsec\GM20780

Dsim\GD10242

Dvir\GJ20069

Dwil\GK10697

Dyak\GE23849

Curated drosophilid orthologs

Dpse\GA14040

Linkouts

InParanoid orthologs - Eukaryotic orthologs

•

ENSANGP00000024014
Anopheles gambiae (Ensembl)
ENSCINP00000017957
Ciona intestinalis (Ensembl)
WBGene00028509
Caenorhabditis briggsae (Wormbase)
WBGene00014096
Caenorhabditis elegans (Wormbase)

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 7 )

Szeged

P{EP}CG1600^EP398

P{EP}CG1600^EP2327

P{lacW}l(2)SH1499^SH1499

VDRC

v19636

w¹¹¹⁸; P{GD9158}v19636

v19637

w¹¹¹⁸; P{GD9158}v19637

Bloomington

17280

w¹¹¹⁸; P{EP}CG1600^EP398/CyO

13973

y¹ w^67c23; P{SUPor-P}CG1600^KG03987

Genomic Clones ( 2 )

cDNA Clones ( 52 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones