A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\CG11107

General Information
SymbolDmel\CG11107SpeciesD. melanogaster
NameCG11107Annotation symbolCG11107
Feature typeprotein_coding_geneFlyBase IDFBgn0033160
Created / Updated2003-12-02/2003-12-02
Genomic Location
Chromosome (arm)2RRecombination map
Cytogenetic map43B2-43B2Sequence location2R:3,274,719..3,278,529 [+]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
This gene is referred to in FlyBase by the symbol CG11107 (FBgn0033160). It has the cytological map location 43B2. Its sequence location is 2R:3274719..3278529. Its molecular function is described as: RNA helicase activity; ATP-dependent RNA helicase activity; ATP-dependent helicase activity; RNA splicing factor activity, transesterification mechanism; structural constituent of ribosome; ATP binding; nucleic acid binding. It is involved in the biological processes: nuclear mRNA splicing, via spliceosome; translation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
43B2-43B2  
Limits computationally determined from genome sequence between P{lacW}cosk16101 and P{EP}CG1600EP398  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Please see the GBrowse view of Dmel\CG11107 for information on other features
detailed view FBtr0089015 FBtr0088966 FBtr0089014 FBtr0110820 FBpp0088087 FBpp0088040 FBpp0088086 FBpp0110117 FBti0026265 FBti0039771 FBti0006375 FBti0059288 FBti0018636 FBti0028389
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
CG11107-RA
FBtr0088966
 NM_136425
  2721
  729
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
CG11107-PA  
FBpp0088040  
82.7  
729  
7.07  
  NP_610269
  AAF59269
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
•
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
DNA/RNA helicase, C-terminal (IPR001650)
Ribosomal protein L29 (IPR001854)
Helicase-associated region (IPR007502)
Region of unknown function DUF1605 (IPR011709)
DEAD-like helicase, N-terminal (IPR014001)
Helicase, superfamily 1 and 2, ATP-binding (IPR014021)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AA202009
 
AA203093
 
AA246626
 
AA263561
 
AA264827
 
AA440794
 
AA441677
 
AA695018
 
AA696529
 
AA803479
 
AA942109
 
AA950488
 
AA951205
 
AA979471
 
AE003841
AAF59269
 
AI124258
 
AI456341
 
AI456571
 
AI456817
 
AI513927
 
AI513928
 
AI515504
 
AI518812
 
AI518952
 
AI519259
 
AI532452
 
AI532462
 
AI543358
 
AI544240
 
AI546520
 
AI546666
 
AY058484
AAL13713
 
BF488350
 
BF492340
 
BF494051
 
BF496142
 
BF502863
 
BF506453
 
BG635520
 
BH214601
 
BI141779
 
BI165220
 
BI166131
 
BI169932
 
BI173898
 
BI212555
 
BI227877
 
BI229550
 
BI230387
 
BI231612
 
BI231670
 
BI233083
 
BI233174
 
BI234190
 
BI234966
 
BI239870
 
BI353483
 
BI353602
 
BI354788
 
BI356266
 
BI357607
 
BI366984
 
BI368694
 
BI373279
 
BI483398
 
BI580244
 
BI637992
 
BI638353
 
CO177622
 
CO185060
 
CO194046
 
CO271919
 
CO280311
 
CO307963
 
CO318786
 
CO331445
 
CO332039
 
CO344674
 
EC051042
 
EC052296
 
EC052557
 
EC053580
 
EC055129
 
EC055574
 
EC056661
 
EC058182
 
EC071638
 
EC079219
 
EC084783
 
EC202217
 
EC227207
 
EC228068
 
EC248431
 
EC255130
 
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    (BDGP Project Members, 2000-)
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        BDGP expression data
        •
        Show all BDGP original images, annotations and embryonic microarray data for CG11107
        FlyExpress - Embryonic expression images (BDGP data)
        •
        Show all FlyExpress processed images for CG11107
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Phenotype manifest in
        Allele
        hide Classical Alleles ( 1 )
        For All Classical Alleles Show

        Allele of CG11107ClassMutagenStocksKnown lesion
        CG11107KG027271 --
        hide Alleles Carried on Transgenic Constructs ( 1 )
        For All Alleles Carried on Transgenic Constructs Show

        Allele of CG11107ClassMutagenStocksKnown lesion
        CG11107GD71992 Yes
        hide Aneuploid Aberrations
        Useful deficiency
         
        hide Transgenic Constructs & Insertions
        Transgenic Constructs
        Type of construct
        Name
        Expression data
        UAS construct
        P{GD7199}
        NA
        Insertions
        Type of insertions
        Name
        Expression data
        miscellaneous insertions
        P{SUPor-P}CG11107KG02727
        NA
        insertion of mobile activating element
        P{GSV1}C371C371
        NA
        hide Related Comments
        Please look at the allele reports for the complete phenotype data
        hide Gene Ontology: Function, Process & Cellular Component ( 11 )
        hide Molecular Function
        CV term
        Evidence
        References
        ATP binding
        inferred from electronic annotation with InterPro:IPR001650
        (FlyBase Curators et al., 2004-)
        ATP-dependent RNA helicase activity
        inferred from sequence or structural similarity with SGD_LOCUS:PRP43; SGD:S0003088
        (Lasko, 2000)
        ATP-dependent helicase activity
        inferred from sequence or structural similarity with EMBL:AB001636
        (FlyBase, 1992-)
        RNA helicase activity
        inferred from sequence or structural similarity
        (Liang and Biggin, 1998)
        inferred from sequence or structural similarity with NCBI_NP:011395 AND inferred from sequence or structural similarity with SGD_LOCUS:PRP43; SGD:S0003088
        (Mount and Salz, 2000)
        RNA splicing factor activity, transesterification mechanism
        inferred from sequence or structural similarity with SGD_LOCUS:PRP43; SGD:S0003088
        (Mount and Salz, 2000)
        nucleic acid binding
        inferred from electronic annotation with InterPro:IPR001650
        (FlyBase Curators et al., 2004-)
        structural constituent of ribosome
        inferred from electronic annotation with InterPro:IPR001854
        (FlyBase Curators et al., 2004-)
        hide Biological Process
        CV term
        Evidence
        References
        nuclear mRNA splicing, via spliceosome
        inferred from sequence or structural similarity with NCBI_NP:011395 AND inferred from sequence or structural similarity with SGD_LOCUS:PRP43; SGD:S0003088
        (Mount and Salz, 2000)
        translation
        inferred from electronic annotation with InterPro:IPR001854
        (FlyBase Curators et al., 2004-)
        hide Cellular Component
        CV term
        Evidence
        References
        ribosome
        inferred from electronic annotation with InterPro:IPR001854
        (FlyBase Curators et al., 2004-)
        spliceosome
        inferred from sequence or structural similarity with SGD_LOCUS:PRP43; SGD:S0003088
        (Mount and Salz, 2000)
        inferred from electronic annotation
        (Roth and Foulger, 2002.4.24)
        hide Sequence Ontology: Class of Gene
        protein_coding_gene
         
        nuclear_gene
         
        hide Interactions & Pathways
        hide Summary of Genetic Interactions
        Interacts with
        Please look at the allele data for full details of the genetic interactions
        CG11107 allele
        Gene
        References
        hide External Data
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        hide Orthologs
        Genome-wide drosophilid orthologs
        Curated drosophilid orthologs
         
        Linkouts
        InParanoid orthologs - Eukaryotic orthologs
        •
        hide Functional Complementation between Species
        hide Inter-Species Misexpression Data
        Produces phenotype in
        Produces NO phenotype in
        hide Stocks & Reagents
        hide Stocks Listed in FlyBase ( 3 )
        VDRC
        v38447
        w1118; P{GD7199}v38447
        v44119
        w1118; P{GD7199}v44119/CyO
        Bloomington
        12911
        y1; P{SUPor-P}CG11107KG02727/CyO; ry506
        hide Genomic Clones ( 1 )
        hide cDNA Clones ( 81 )
        Please Note
        This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
        cDNA Clones, Fully Sequenced
        BDGP DGC clones
        Other clones
        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        hide RNAi & Array Information
        Affy Oligo
        Linkouts
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        hide Antibody Information
        hide Other Information
        hide Discoverer
        hide Etymology
        hide Identification
        hide Position Effect Variegation Data
        hide Relationship to Other Genes
        Source for database identity of
        Source for database merge of
        Source for merge of: CG11107 anon-EST:Liang-1.18
        (Ashburner, 2004.6.30)
        Additional comments
        hide Comments About Role
        hide Comments About Molecular Function
        hide Other Comments
        hide External Crossreferences & Linkouts
        Sequence Crossreferences
        RefSeq (Transcripts)
        •
        RefSeq (Proteins)
        •
        DDBJ / EMBL / GenBank
        •
        UniProtKB/TrEMBL
        •
        Other Crossreferences