A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Gene Dmel\CG10949

General Information
SymbolDmel\CG10949SpeciesD. melanogaster
NameCG10949Annotation symbolCG10949
Feature typeprotein_coding_geneFlyBase IDFBgn0032858
Created / Updated2004-08-09/2004-08-09
Genomic Location
Chromosome (arm)2LRecombination map
Cytogenetic map 38C6-38C6 Sequence location2L:20,415,171..20,416,918 [-]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
This gene is referred to in FlyBase by the symbol CG10949 (FBgn0032858). It has the cytological map location 38C6. Its sequence location is 2L:20415171..20416918. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
38C6-38C6  
Limits computationally determined from genome sequence between P{EP}CG16798EP401&P{lacW}k07219 and P{lacW}k02501&P{lacW}k14810  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
In direction of increasing cytology: anon-38C.45+ CG10949- Arc-p34+
(Butler et al., 2001)
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Please see the GBrowse view of Dmel\CG10949 for information on other features
detailed view FBtr0081367 FBtr0081358 FBpp0080899 FBpp0080890 FBti0075460 FBti0026332 FBti0075956 FBti0048761 FBti0025970 FBti0023148
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
CG10949-RA
FBtr0081367
 NM_136188
  1691
  459
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
CG10949-PA  
FBpp0080899  
53.2  
459  
5.11  
  NP_610032
  AAF53891
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
•
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
MADF (IPR006578)
HMG-I and HMG-Y, DNA-binding (IPR000637)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AA699158
 
AC006402
 
AE003666
AAF53891
 
AI402729
 
AY058441
AAL13670
 
BF504410
 
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
    Maps to
    (Butler et al., 2001)
    Does NOT map to
    Identified with
    (BDGP Project Members, 2000-, Butler, 2001)
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide Microarray Data
        Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002)
        Untitled Document detailed view FBtr0081367 FBtr0081358
        AI402729
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Phenotype manifest in
        Allele
        hide Classical Alleles ( 1 )
        For All Classical Alleles Show

        Allele of CG10949ClassMutagenStocksKnown lesion
        CG10949EY211711 --
        hide Alleles Carried on Transgenic Constructs ( 1 )
        For All Alleles Carried on Transgenic Constructs Show

        Allele of CG10949ClassMutagenStocksKnown lesion
        CG10949GD71402 Yes
        hide Aneuploid Aberrations
        Useful deficiency
         
        Disrupted in
        (Ryder, 2004.4.26)
        hide Transgenic Constructs & Insertions
        Transgenic Constructs
        Type of construct
        Name
        Expression data
        UAS construct
        P{GD7140}
        NA
        Insertions
        Type of insertions
        Name
        Expression data
        insertion of mobile activating element
        P{EPgy2}CG10949EY21171
        NA
        insertion of enhancer trap
        P{lacW}l(2)SH0251SH0251
        No
        hide Related Comments
        Please look at the allele reports for the complete phenotype data
        hide Gene Ontology: Function, Process & Cellular Component ( 0 )
        hide Molecular Function
        CV term
        Evidence
        References
        hide Biological Process
        CV term
        Evidence
        References
        hide Cellular Component
        CV term
        Evidence
        References
        hide Sequence Ontology: Class of Gene
        protein_coding_gene
         
        nuclear_gene
         
        hide Interactions & Pathways
        hide Summary of Genetic Interactions
        Interacts with
        Please look at the allele data for full details of the genetic interactions
        CG10949 allele
        Gene
        References
        hide External Data
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        hide Orthologs
        Genome-wide drosophilid orthologs
        Curated drosophilid orthologs
         
        Linkouts
        hide Functional Complementation between Species
        hide Inter-Species Misexpression Data
        Produces phenotype in
        Produces NO phenotype in
        hide Stocks & Reagents
        hide Stocks Listed in FlyBase ( 4 )
        VDRC
        v38426
        w1118; P{GD7140}v38426
        v38425
        w1118; P{GD7140}v38425/TM3
        Szeged
        -
        P{lacW}l(2)SH0251SH0251
        Bloomington
        22455
        y1 w67c23; P{EPgy2}CG10949EY21171
        hide Genomic Clones ( 2 )
        hide cDNA Clones ( 3 )
        cDNA Clones, Fully Sequenced
        BDGP DGC clones
        Other clones
        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        hide RNAi & Array Information
        Affy Oligo
        Linkouts
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        hide Antibody Information
        hide Other Information
        hide Discoverer
        hide Etymology
        hide Identification
        hide Position Effect Variegation Data
        hide Relationship to Other Genes
        Source for database identity of
        Source for database merge of
        Additional comments
        hide Comments About Role
        hide Comments About Molecular Function
        hide Other Comments
        hide External Crossreferences & Linkouts
        Sequence Crossreferences
        RefSeq (Transcripts)
        •
        RefSeq (Proteins)
        •
        DDBJ / EMBL / GenBank
        •
        UniProtKB/TrEMBL
        •
        Other Crossreferences
        InterPro domains - A database of protein families, domains, and functional sites
        •
        MADF (IPR006578)
        HMG-I and HMG-Y, DNA-binding (IPR000637)
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        DEDB - Drosophila exon database: splicing graphs
        •
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        PANTHER - Protein classification by function, families, and pathways
        •
        University of Chicago Dev. Expression
        •
        hide Synonyms & Secondary IDs ( 3 )
        Reported As
        Symbol Synonym
        38C.46
        (McGill Drosophila Genome Project, 2001.9.25, Butler, 2001, Butler et al., 2001)
        CG10949
         
        FBgn0032858
        (Raychaudhuri et al., 2003)
        Name Synonym
        CG10949
         
        Secondary FlyBase IDs
          hide References ( 14 )
          Research paper
          Raychaudhuri et al., 2003, Nucleic Acids Res. 31(15): 4553--4560
          The computational analysis of scientific literature to define and recognize gene expression clusters. [FBrf0160870]
          Arbeitman et al., 2002, Science 297(5590): 2270--2275
          Gene expression during the life cycle of Drosophila melanogaster. [FBrf0152339]
          Butler et al., 2001, Genetics 158(4): 1597--1614
          Map position and expression of the genes in the 38 region of Drosophila. [FBrf0138405]
          Ponting et al., 2001, Genome Res. 11(12): 1996--2008
          Novel protein domains and repeats in Drosophila melanogaster: insights into structure, function, and evolution. [FBrf0141558]
          Supplementary material
          Giot et al., 2003, Science 302(5651):
          Tables S1 to S7. [FBrf0166452]
          Oh et al., 2003, Genetics 163(1):
          Table S1. [FBrf0157097]
          Butler, 2001, Genetics 158(4):
          Supplemental Material 3. Gene predictions and transcripts of the cytological region 38. [FBrf0139854]
          Personal communication to FlyBase
          Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center
          RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
          Bellen, 2006.8.3, MBBatch686_2.xml
          MBBatch686_2.xml [FBrf0191805]
          Ryder, 2004.4.26, Exelixis CG deletion data.
          Exelixis CG deletion data. [FBrf0184335]
          McGill Drosophila Genome Project, 2001.9.25, FASTA sequences of Gene Predictions of the 38 region.
          FASTA sequences of Gene Predictions of the 38 region. [FBrf0139855]
          FlyBase analysis
          FlyBase, 1992-, FlyBase curation
          FlyBase curation. [FBrf0105495]
          Computer file
          BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.
          Berkeley Drosophila Genome Project. [FBrf0125078]
          Automatic genome annotation
          FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.]
          [Annotations performed at the Celera Jamboreee.] [FBrf0126705]