A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\CG15141

General Information
SymbolDmel\CG15141SpeciesD. melanogaster
NameCG15141Annotation symbolCG15141
Feature typeprotein_coding_geneFlyBase IDFBgn0032635
Created / Updated2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)2LRecombination map
Cytogenetic map36C7-36C7Sequence location2L:17,410,657..17,413,505 [+]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
This gene is referred to in FlyBase by the symbol CG15141 (FBgn0032635). It has the cytological map location 36C7. Its sequence location is 2L:17410657..17413505. Its molecular function is described as: protein binding; zinc ion binding; ubiquitin-protein ligase activity. It is involved in the biological process ubiquitin cycle. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
36C7-36C7  
Limits computationally determined from genome sequence between P{lacW}Mhck10423&P{lacW}Cask03902 and P{lacW}Aac11k06710  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Please see the GBrowse view of Dmel\CG15141 for information on other features
detailed view FBtr0080975 FBtr0080976 FBtr0290261 FBtr0080977 FBtr0290265 FBtr0081011 FBtr0080979 FBtr0081010 FBtr0081008 FBtr0081009 FBpp0080529 FBpp0080528 FBpp0288700 FBpp0080530 FBpp0288704 FBpp0080564 FBpp0080532 FBpp0080563 FBpp0080562 FBpp0080561 FBti0078340 FBti0044946 FBti0066731 FBti0065586 FBti0043806 FBti0040969 FBti0034293 FBti0024537
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
CG15141-RA
FBtr0080979
 NM_135993
  1673
  404
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
CG15141-PA  
FBpp0080532  
46.0  
404  
4.56  
  NP_609837
  AAF53607
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
•
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
Zinc finger, N-recognin (IPR003126)
Zinc finger, PHD-type (IPR001965)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AA201371
 
AA390809
 
AA391395
 
AA392224
 
AA441563
 
AA539368
 
AA539439
 
AA540117
 
AA540123
 
AA540129
 
AA803405
 
AA816384
 
AA816480
 
AA820279
 
AA820904
 
AA942014
 
AA950075
 
AA979334
 
AE003655
AAF53607
 
AI109019
 
AI455545
 
AI457046
 
AI511667
 
AI515216
 
AI515828
 
AI517581
 
AI518639
 
AI520234
 
AY051712
AAK93136
 
BH854583
 
BI142096
 
BI167004
 
BI168794
 
BI170512
 
BI173370
 
BI216887
 
BI227611
 
BI231523
 
BI234472
 
BI237035
 
BI238516
 
BI241649
 
BI242258
 
BI356518
 
BI356998
 
BI361671
 
BI362310
 
BI364525
 
BI366647
 
BI369755
 
BI369782
 
BI484779
 
BI578855
 
BI579402
 
BI579522
 
CK658461
 
CO177959
 
CO264997
 
CO275464
 
CO282052
 
CO299989
 
CO309060
 
CO339430
 
EC073566
 
EC089167
 
EC209538
 
EC211091
 
EC241638
 
EC256732
 
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    (BDGP Project Members, 2000-, Oliver, 2001.8.16)
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        FlyExpress - Embryonic expression images (BDGP data)
        •
        Show all FlyExpress processed images for CG15141
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Phenotype manifest in
        Allele
        hide Classical Alleles ( 1 )
        For All Classical Alleles Show

        Allele of CG15141ClassMutagenStocksKnown lesion
        CG15141KG060051 --
        hide Alleles Carried on Transgenic Constructs ( 1 )
        For All Alleles Carried on Transgenic Constructs Show

        Allele of CG15141ClassMutagenStocksKnown lesion
        CG15141GD89191 Yes
        hide Aneuploid Aberrations
        Useful deficiency
         
        Disrupted in
        (Ryder, 2004.4.26)
        (Ryder, 2004.4.26)
        hide Transgenic Constructs & Insertions
        Transgenic Constructs
        Type of construct
        Name
        Expression data
        UAS construct
        P{GD8919}
        NA
        Insertions
        Type of insertions
        Name
        Expression data
        miscellaneous insertions
        P{SUPor-P}CG15141KG06005
        NA
        hide Related Comments
        Please look at the allele reports for the complete phenotype data
        hide Gene Ontology: Function, Process & Cellular Component ( 4 )
        hide Molecular Function
        CV term
        Evidence
        References
        protein binding
        inferred from electronic annotation with InterPro:IPR001965
        (FlyBase Curators et al., 2004-)
        ubiquitin-protein ligase activity
        inferred from electronic annotation with InterPro:IPR003126
        (FlyBase Curators et al., 2004-)
        zinc ion binding
        inferred from electronic annotation with InterPro:IPR001965, InterPro:IPR003126
        (FlyBase Curators et al., 2004-)
        hide Biological Process
        CV term
        Evidence
        References
        ubiquitin cycle
        inferred from electronic annotation with InterPro:IPR003126
        (FlyBase Curators et al., 2004-)
        hide Cellular Component
        CV term
        Evidence
        References
        hide Sequence Ontology: Class of Gene
        protein_coding_gene
         
        nuclear_gene
         
        hide Interactions & Pathways
        hide Summary of Genetic Interactions
        Interacts with
        Please look at the allele data for full details of the genetic interactions
        CG15141 allele
        Gene
        References
        hide External Data
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        hide Orthologs
        Genome-wide drosophilid orthologs
        Curated drosophilid orthologs
         
        Linkouts
        InParanoid orthologs - Eukaryotic orthologs
        •
        hide Functional Complementation between Species
        hide Inter-Species Misexpression Data
        Produces phenotype in
        Produces NO phenotype in
        hide Stocks & Reagents
        hide Stocks Listed in FlyBase ( 2 )
        VDRC
        v19307
        w1118; P{GD8919}v19307/CyO
        Bloomington
        14465
        y1; P{SUPor-P}CG15141KG06005/CyO; ry506
        hide Genomic Clones ( 2 )
        hide cDNA Clones ( 59 )
        Please Note
        This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
        cDNA Clones, Fully Sequenced
        BDGP DGC clones
        Other clones
        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        hide RNAi & Array Information
        Affy Oligo
        Linkouts
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        hide Antibody Information
        hide Other Information
        hide Discoverer
        hide Etymology
        hide Identification
        hide Position Effect Variegation Data
        hide Relationship to Other Genes
        Source for database identity of
        Source for database merge of
        Source for merge of: CG15141 BEST:LD24839
        (Rana, 2004.7.8)
        Additional comments
        hide Comments About Role
        hide Comments About Molecular Function
        hide Other Comments
        hide External Crossreferences & Linkouts
        Sequence Crossreferences
        RefSeq (Transcripts)
        •
        RefSeq (Proteins)
        •
        DDBJ / EMBL / GenBank
        •
        UniProtKB/TrEMBL
        •
        Other Crossreferences
        InterPro domains - A database of protein families, domains, and functional sites
        •
        Zinc finger, N-recognin (IPR003126)
        Zinc finger, PHD-type (IPR001965)
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        DEDB - Drosophila exon database: splicing graphs
        •
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        FlyExpress - Embryonic expression images (BDGP data)
        •
        FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        InParanoid orthologs - Eukaryotic orthologs
        •
        PANTHER - Protein classification by function, families, and pathways
        •
        hide Synonyms & Secondary IDs ( 2 )
        Reported As
        Symbol Synonym
        BEST:LD24839
         
        CG15141
        (Altenhein et al., 2006, Bienz, 2006)
        Name Synonym
        CG15141
         
        Secondary FlyBase IDs
        • FBgn0046264
        hide References ( 14 )
        Research paper
        Altenhein et al., 2006, Dev. Biol. 296(2): 545--560
        Expression profiling of glial genes during Drosophila embryogenesis. [FBrf0195367]
        Herr and Harris, 2004, FEBS Lett. 572(1-3): 147--153
        Close head-to-head juxtaposition of genes favors their coordinate regulation in Drosophila melanogaster. [FBrf0179781]
        Supplementary material
        Giot et al., 2003, Science 302(5651):
        Tables S1 to S7. [FBrf0166452]