Gene Dmel\CG2839

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General Information

Symbol

Dmel\CG2839

Species

D. melanogaster

Name

CG2839

Annotation symbol

CG2839

Feature type

protein_coding_gene

FlyBase ID

FBgn0031273

Created / Updated

2003-12-01/2003-12-01

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

21E2-21E2

Sequence location

2L:625,663..628,143 [+]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol CG2839 (FBgn0031273). It has the cytological map location 21E2. Its sequence location is 2L:625663..628143. Its molecular function is described as binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

21E2-21E2

Limits computationally determined from genome sequence between P{lacW}l(2)k09610^k09610&P{lacW}S^k09538a and P{PZ}l(2)10685¹⁰⁶⁸⁵&P{lacW}Tango14^k00619

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\CG2839 for information on other features

Comments on Gene Model

<new comment>No stop codon prior to A-rich repeat region (GA[n] repeats); results in transcript of low complexity in 3' region (approximately 1.63 kb). Protein homology to accessory gland proteins restricted to 5' non-repeat region.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG2839-RA

FBtr0077999

NM_134696

2481

826

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG2839-PA

FBpp0077664

106.0

826

9.58

NP_608540

AAF51469

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

C-type lectin (IPR001304)

C-type lectin-like (IPR016186)

C-type lectin fold (IPR016187)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VPS3

Maps to

Does NOT map to

Identified with

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

DEDB - Drosophila exon database: splicing graphs

•

5784

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0031273

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0031273

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of CG2839	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 2 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG2839	Class	Mutagen	Stocks	Known lesion
CG2839^GD16617		in vitro construct \| RNAi in vitro construct \| regulatory fusion	0	Yes
CG2839^GD6837		in vitro construct \| RNAi in vitro construct \| regulatory fusion	1	Yes

Aneuploid Aberrations

Useful deficiency

Df(2L)S3

Useful duplication

Dp(2;2)M24F⁺14

Disrupted in

Df(2L)Exel8003

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD16617}

P{GD6837}

Insertions

Type of insertions

Name

Expression data

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 1 )

Molecular Function

CV term

Evidence

References

binding

inferred from electronic annotation with InterPro:IPR001304, InterPro:IPR016186, InterPro:IPR016187

(FlyBase Curators et al., 2004-)

Biological Process

CV term

Evidence

References

Cellular Component

CV term

Evidence

References

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG2839 allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

59499

Orthologs

Genome-wide drosophilid orthologs

Dsim\GD23040

Dyak\GE16990

Curated drosophilid orthologs

Linkouts

InParanoid orthologs - Eukaryotic orthologs

•

ENSBTAP00000009295
Bos taurus (Ensembl)
NEWSINFRUP00000178834
Takifugu rubripes (Ensembl)
ENSGALP00000021314
Gallus gallus (Ensembl)
ENSP00000290632
Homo sapiens (Ensembl)
ENSMMUP00000022408
Macaca mulatta (Ensembl)
ENSMODP00000023725
Monodelphis domestica (Ensembl)
Q7XXP7
Oryza sativa (Gramene)
WBGene00000100
Caenorhabditis elegans (Wormbase)
DDB0188541
Dictyostelium discoideum (Dictybase)
DDB0217043
Dictyostelium discoideum (Dictybase)
MGI:2177944
Mus musculus (Informatics)

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 1 )

VDRC

v17952

w¹¹¹⁸; P{GD6837}v17952

Genomic Clones ( 1 )

BACR48E08

cDNA Clones ( 0 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Affy Oligo

Linkouts

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0031273

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0031273

Antibody Information

Other Information

Discoverer

Etymology

Identification

Position Effect Variegation Data

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Comments About Role

Comments About Molecular Function

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_134696

RefSeq (Proteins)

•

NP_608540

DDBJ / EMBL / GenBank

•

UniProtKB/TrEMBL

•

Q9VPS3

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

C-type lectin (IPR001304)

C-type lectin-like (IPR016186)

C-type lectin fold (IPR016187)

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

59499

DEDB - Drosophila exon database: splicing graphs

•

5784

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0031273

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0031273

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0031273

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0031273

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0031273

InParanoid orthologs - Eukaryotic orthologs

•

ENSBTAP00000009295
Bos taurus (Ensembl)
NEWSINFRUP00000178834
Takifugu rubripes (Ensembl)
ENSGALP00000021314
Gallus gallus (Ensembl)
ENSP00000290632
Homo sapiens (Ensembl)
ENSMMUP00000022408
Macaca mulatta (Ensembl)
ENSMODP00000023725
Monodelphis domestica (Ensembl)
Q7XXP7
Oryza sativa (Gramene)
WBGene00000100
Caenorhabditis elegans (Wormbase)
DDB0188541
Dictyostelium discoideum (Dictybase)
DDB0217043
Dictyostelium discoideum (Dictybase)
MGI:2177944
Mus musculus (Informatics)

Synonyms & Secondary IDs ( 1 )

Reported As

Symbol Synonym

CG2839

(Tanji et al., 2006)

Name Synonym

CG2839

Secondary FlyBase IDs

References ( 9 )

Research paper

Tanji et al., 2006, Biochem. J. 396(1): 127--138: Participation of a galactose-specific C-type lectin in Drosophila immunity. [FBrf0189817]
Bouyain et al., 2002, J. Biol. Chem. 277(25): 22566--22572: An endogenous Drosophila receptor for glycans bearing alpha 1,3-linked core fucose residues. [FBrf0149058]

Supplementary material

Dietzl et al., 2007, Nature 448(7150):: Supplementary Table 1. [FBrf0202579]

Personal communication to FlyBase

Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]

FlyBase analysis

FlyBase, 1992-, FlyBase curation: FlyBase curation. [FBrf0105495]

Curated genome annotation

Ashburner, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126651]

Automatic genome annotation

FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126705]