A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\CG6891

General Information
SymbolDmel\CG6891SpeciesD. melanogaster
NameCG6891Annotation symbolCG6891
Feature typeprotein_coding_geneFlyBase IDFBgn0030955
Created / Updated2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)XRecombination map
Cytogenetic map17D4-17D5Sequence locationX:18,669,263..18,675,378 [+]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
This gene is referred to in FlyBase by the symbol CG6891 (FBgn0030955). It has the cytological map location 17D4-17D5. Its sequence location is X:18669263..18675378. Its molecular function is described as actin binding. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides.

hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
17D4-17D5  
Limits computationally determined from genome sequence between P{EP}EP443EP443&P{EP}BxEP1383 and P{EP}Pk17EEP438  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Please see the GBrowse view of Dmel\CG6891 for information on other features
detailed view FBtr0113003 FBtr0074631 FBtr0074632 FBtr0074661 FBpp0111916 FBpp0074402 FBpp0074403 FBpp0074432 FBti0021476 FBti0035744 FBti0024150 FBti0071214 FBti0018675
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
CG6891-RA
FBtr0074631
 NM_133095
  992
  163
CG6891-RB
FBtr0074632
 NM_167630
  736
  146
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
CG6891-PA  
FBpp0074402  
18.6  
163  
4.61  
  NP_573323
  AAF48881
CG6891-PB  
FBpp0074403  
16.6  
146  
4.63  
  NP_728196
  AAN09475
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
Actin-binding, cofilin/tropomyosin type (IPR002108)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AE003510
AAF48881
 
AE003510
AAN09475
 
AI260509
 
AI295342
 
AI296852
 
AI534384
 
AW944108
 
AY122215
AAM52727
 
BG637442
 
BH214645
 
BI163502
 
BI169586
 
BI170299
 
BI236859
 
BI241700
 
BI486504
 
BI581269
 
BI616478
 
BI633536
 
BI635114
 
BI637678
 
BP553541
 
BP553542
 
BP560282
 
BP560283
 
CA803904
 
CK657137
 
CK658058
 
CK659096
 
CK659124
 
CK659488
 
CK662180
 
CO184447
 
CO194834
 
CO281856
 
CO283140
 
CO318641
 
CO330898
 
CO338529
 
EC062330
 
EC203537
 
EC204443
 
EC245687
 
EC250171
 
EC250243
 
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    (BDGP Project Members, 2000-)
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Phenotype manifest in
        Allele
        hide Classical Alleles ( 1 )
        For All Classical Alleles Show

        Allele of CG6891ClassMutagenStocksKnown lesion
        CG6891KG033061 --
        hide Alleles Carried on Transgenic Constructs ( 2 )
        For All Alleles Carried on Transgenic Constructs Show

        Allele of CG6891ClassMutagenStocksKnown lesion
        CG6891GD107580 Yes
        CG6891GD172942 Yes
        hide Aneuploid Aberrations
        Useful deficiency
         
        Useful duplication
         
        Disrupted in
        (Ryder, 2004.4.26)
        hide Transgenic Constructs & Insertions
        Transgenic Constructs
        Type of construct
        Name
        Expression data
        UAS construct
        P{GD10758}
        NA
        P{GD13712}
        NA
        P{GD17294}
        NA
        Insertions
        Type of insertions
        Name
        Expression data
        miscellaneous insertions
        P{SUPor-P}CG6891KG03306
        NA
        hide Related Comments
        Please look at the allele reports for the complete phenotype data
        hide Gene Ontology: Function, Process & Cellular Component ( 2 )
        hide Molecular Function
        CV term
        Evidence
        References
        actin binding
        inferred from electronic annotation with InterPro:IPR002108
        (FlyBase Curators et al., 2004-)
        hide Biological Process
        CV term
        Evidence
        References
        hide Cellular Component
        CV term
        Evidence
        References
        intracellular
        inferred from electronic annotation with InterPro:IPR002108
        (FlyBase Curators et al., 2004-)
        hide Sequence Ontology: Class of Gene
        protein_coding_gene
         
        nuclear_gene
         
        hide Interactions & Pathways
        hide Summary of Genetic Interactions
        Interacts with
        Please look at the allele data for full details of the genetic interactions
        CG6891 allele
        Gene
        References
        hide External Data
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        hide Orthologs
        Genome-wide drosophilid orthologs
        Curated drosophilid orthologs
         
        Linkouts
        InParanoid orthologs - Eukaryotic orthologs
        •
        hide Functional Complementation between Species
        hide Inter-Species Misexpression Data
        Produces phenotype in
        Produces NO phenotype in
        hide Stocks & Reagents
        hide Stocks Listed in FlyBase ( 3 )
        VDRC
        v50054
        w1118; P{GD17294}v50054
        v50055
        w1118; P{GD17294}v50055/CyO
        Bloomington
        12888
        y1 P{SUPor-P}CG6891KG03306
        hide Genomic Clones ( 1 )
        hide cDNA Clones ( 30 )
        Please Note
        This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
        cDNA Clones, Fully Sequenced
        BDGP DGC clones
        Other clones
        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        hide RNAi & Array Information
        Affy Oligo
        Linkouts
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        hide Antibody Information
        hide Other Information
        hide Discoverer
        hide Etymology
        hide Identification
        hide Position Effect Variegation Data
        hide Relationship to Other Genes
        Source for database identity of
        Source for database merge of
        Additional comments
        hide Comments About Role
        hide Comments About Molecular Function
        hide Other Comments
        hide External Crossreferences & Linkouts
        Sequence Crossreferences
        RefSeq (Transcripts)
        •
        RefSeq (Proteins)
        •
        DDBJ / EMBL / GenBank
        •
        UniProtKB/TrEMBL
        •
        Other Crossreferences
        InterPro domains - A database of protein families, domains, and functional sites
        •
        Actin-binding, cofilin/tropomyosin type (IPR002108)
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        DEDB - Drosophila exon database: splicing graphs
        •
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        InParanoid orthologs - Eukaryotic orthologs
        •
        hide Synonyms & Secondary IDs ( 1 )
        Reported As
        Symbol Synonym
        CG6891
         
        Name Synonym
        CG6891
         
        Secondary FlyBase IDs
          hide References ( 10 )
          Research paper
          de Morais Guedes et al., 2003, Biochem. biophys. Res. Commun. 312(3): 545--554
          Drosophila melanogaster larval hemolymph protein mapping. [FBrf0167337]
          Supplementary material
          Dietzl et al., 2007, Nature 448(7150):
          Supplementary Table 1. [FBrf0202579]
          Giot et al., 2003, Science 302(5651):
          Tables S1 to S7. [FBrf0166452]
          Personal communication to FlyBase
          Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center
          RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
          FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.
          Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
          Ryder, 2004.4.26, Exelixis CG deletion data.
          Exelixis CG deletion data. [FBrf0184335]
          FlyBase analysis
          FlyBase, 1992-, FlyBase curation
          FlyBase curation. [FBrf0105495]
          Computer file
          Gene Disruption Project members, 2001-, [title not yet available]
          [title not yet available] [FBrf0132177]
          BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.
          Berkeley Drosophila Genome Project. [FBrf0125078]
          Curated genome annotation
          Kodira, 1999.11, [Annotations performed at the Celera Jamboreee.]
          [Annotations performed at the Celera Jamboreee.] [FBrf0126678]