Gene Dmel\CG11696

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General Information

Symbol

Dmel\CG11696

Species

D. melanogaster

Name

CG11696

Annotation symbol

CG11696

Feature type

protein_coding_gene

FlyBase ID

FBgn0030314

Created / Updated

2003-12-01/2003-12-01

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

10C7-10C7

Sequence location

X:11,467,834..11,470,183 [+]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol CG11696 (FBgn0030314). It has the cytological map location 10C7. Its sequence location is X:11467834..11470183. Its molecular function is described as zinc ion binding. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

10C7-10C7

Limits computationally determined from genome sequence between P{EP}CG32666^EP1452 and P{EP}Ptp10D^EP1172

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\CG11696 for information on other features

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG11696-RA

FBtr0073512

NM_132503

2163

664

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG11696-PA

FBpp0073361

75.8

664

7.11

NP_572731

AAF48061

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

PANTHER - Protein classification by function, families, and pathways

•

FBgn0030314

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

HMG-I and HMG-Y, DNA-binding (IPR000637)

Zinc finger, C2H2-type (IPR007087)

Zinc finger, AD-type (IPR012934)

Zinc finger, C2H2-like (IPR015880)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VYX2

Maps to

Does NOT map to

Identified with

LD18373

(BDGP Project Members, 2000-)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

DEDB - Drosophila exon database: splicing graphs

•

2506

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0030314

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0030314

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0030314

BDGP expression data

•

Show all BDGP original images, annotations and embryonic microarray data for CG11696

FlyExpress - Embryonic expression images (BDGP data)

•

Show all FlyExpress processed images for CG11696

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of CG11696	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG11696	Class	Mutagen	Stocks	Known lesion
CG11696^GD7365		in vitro construct \| RNAi in vitro construct \| regulatory fusion	0	Yes

Aneuploid Aberrations

Useful deficiency

Df(1)m259-4

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD7365}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

P{SUPor-P}KG01708

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 2 )

Molecular Function

CV term

Evidence

References

zinc ion binding

inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR012934, InterPro:IPR015880

(FlyBase Curators et al., 2004-)

Biological Process

CV term

Evidence

References

Cellular Component

CV term

Evidence

References

nucleus

inferred from electronic annotation with InterPro:IPR012934

(FlyBase Curators et al., 2004-)

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG11696 allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

58514

Drosophila PIMRider - The Drosophila Protein Interaction map

•

521984

Orthologs

Genome-wide drosophilid orthologs

Dana\GF20321

Dper\GL26740

Dpse\GA11148

Dyak\GE15947

Curated drosophilid orthologs

Dpse\GA11148

Linkouts

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 1 )

Bloomington

14382

y¹ P{SUPor-P}KG01708; ry⁵⁰⁶

Genomic Clones ( 1 )

BACR26B05

cDNA Clones ( 7 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

LD18373

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Affy Oligo

Linkouts

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0030314

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0030314

Antibody Information

Other Information

Discoverer

Etymology

Identification

Position Effect Variegation Data

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Comments About Role

Comments About Molecular Function

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_132503

RefSeq (Proteins)

•

NP_572731

DDBJ / EMBL / GenBank

•

UniProtKB/TrEMBL

•

Q9VYX2

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

HMG-I and HMG-Y, DNA-binding (IPR000637)

Zinc finger, C2H2-type (IPR007087)

Zinc finger, AD-type (IPR012934)

Zinc finger, C2H2-like (IPR015880)

Linkouts

BDGP expression data

•

Show all BDGP original images, annotations and embryonic microarray data for CG11696

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

58514

DEDB - Drosophila exon database: splicing graphs

•

2506

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0030314

Drosophila PIMRider - The Drosophila Protein Interaction map

•

521984

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0030314

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0030314

FlyExpress - Embryonic expression images (BDGP data)

•

FBgn0030314

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0030314

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0030314

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0030314

PANTHER - Protein classification by function, families, and pathways

•

FBgn0030314

Synonyms & Secondary IDs ( 2 )

Reported As

Symbol Synonym

(Lee et al., 2004)

CG11696

Name Synonym

CG11696

Secondary FlyBase IDs

References ( 10 )

Research paper

Lee et al., 2004, J. Biol. Chem. 279(46): 47740--47745: MLE functions as a transcriptional regulator of the roX2 gene. [FBrf0179837]
Brody et al., 2002, Mech. Dev. 113(1): 41--59: Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. [FBrf0147137]

Supplementary material

Dietzl et al., 2007, Nature 448(7150):: Supplementary Table 1. [FBrf0202579]
Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]

Personal communication to FlyBase

FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]

FlyBase analysis

FlyBase, 1992-, FlyBase curation: FlyBase curation. [FBrf0105495]

Computer file

Gene Disruption Project members, 2001-, [title not yet available]: [title not yet available] [FBrf0132177]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.: Berkeley Drosophila Genome Project. [FBrf0125078]

Automatic genome annotation

FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126705]

Curated genome annotation

Lei, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126680]