• Home
• Tools
  • BLAST
  • GBrowse
  • QueryBuilder
  • TermLink
  • ImageBrowse
  • Interactions Browser
  • Apollo
  • CytoSearch
  • QuickSearch
  • Batch Download
  • Coordinate Converter
  • Google™ FlyBase
  • Find A Person
  • Update An Address
  • Add A New Person
• Files
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases FTP
  • Genomes FTP
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Synteny Table
  • Drosophilidae
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All resources
  • Interactive Fly
  • Textpresso for Fly
  • AAA site
  • BDGP
  • DHGP
  • DGRC
  • Model Organisms
  • Stock Collections:
  • Bloomington
  • DrosDel
  • Ehime
  • Exelixis (Harvard)
  • GDP (Baylor)
  • Kyoto
  • NIG-Fly
  • Szeged
  • Tucson
  • VDRC
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Known Problems
  • Contact FlyBase
• Archives
  • Prior Home Page
  • R4.3 BLAST
  • R4.3 GBrowse
  • Older Archives

Gene Dmel\Imp

General Information
Symbol	Dmel\Imp	Species	D. melanogaster
Name	IGF-II mRNA-binding protein	Annotation symbol	CG1691
Feature type	protein_coding_gene	FlyBase ID	FBgn0030235
Created / Updated	2003-12-01/2006-05-09
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	9F2-9F4	Sequence location	X:10,690,030..10,716,815 [-]
Map ( GBrowse )	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene IGF-II mRNA-binding protein is referred to in FlyBase by the symbol Imp (CG1691, FBgn0030235). It has the cytological map location 9F2-9F4. Its sequence location is X:10690030..10716815. Its molecular function is described as mRNA binding. The biological processes in which it is involved are not known. 28 alleles are reported. The phenotype of these alleles is annotated with macrochaeta. It has 9 annotated transcripts and 9 annotated polypeptides.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 9F2-9F4   Limits computationally determined from genome sequence between P{EP}sesBEP319&P{EP}ImpEP760 and P{EP}EP1321EP1321&P{EP}CG2061EP1537
Experimentally Determined Cytological Location
Cytogenetic map Notes References 9F1-9F4 (determined by in situ hybridisation)   (Schaefer et al., 1999.6.15) 9C3-9C4 (determined by in situ hybridisation)   (Schaefer et al., 1999.3.29)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology) References Gene Order (overall orientation not stated) References Overall orientation not stated: sbr- Imp- (Korey et al., 2001)
Gene Model & Products
Please see the GBrowse view of Dmel\Imp for information on other features
Comments on Gene Model
	High degree of variablity in transcription start sites, number and structure of 5' exons; EST data suggest additional transcripts, producing additional 5' variations. EST data suggest variability in extent of 3' UTR.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Imp-RA FBtr0073420  NM_078556   3296   566 Imp-RB FBtr0073419  NM_167254   2856   566 Imp-RC FBtr0073418  NM_167255   3269   566 Imp-RD FBtr0073416  NM_167249   3549   573 Imp-RE FBtr0073417  NM_167250   3636   573 Imp-RF FBtr0073413  NM_167251   3917   573 Imp-RG FBtr0073415  NM_167252   3919   573 Imp-RH FBtr0073414  NM_167253   3884   573 Imp-RI FBtr0110967  NM_001042803   2839   588
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kD) Length (aa) Theoretical pI RefSeq ID GenBank protein Imp-PA   FBpp0073276   62.1   566   10.16     NP_511111   AAF47958 Imp-PB   FBpp0073275   62.1   566   10.16     NP_727456   AAN09274 Imp-PC   FBpp0073274   62.1   566   10.16     NP_727457   AAN09275 Imp-PD   FBpp0073272   62.7   573   9.32     NP_727451   AAN09269 Imp-PE   FBpp0073273   62.7   573   9.32     NP_727452   AAN09270 Imp-PF   FBpp0073269   62.7   573   9.32     NP_727453   AAN09271 Imp-PG   FBpp0073271   62.7   573   9.32     NP_727454   AAN09272 Imp-PH   FBpp0073270   62.7   573   9.32     NP_727455   AAN09273 Imp-PI   FBpp0110267   64.5   588   9.33     NP_001036268   ABI30974
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts	PANTHER - Protein classification by function, families, and pathways • FBgn0030235
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • K Homology (IPR004087) K Homology, type 1 (IPR004088)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA142188   AA142189   AA433245   AA735742   AE003484 AAF47958   AE003484 AAN09269   AE003484 AAN09270   AE003484 AAN09271   AE003484 AAN09272   AE003484 AAN09273   AE003484 AAN09274   AE003484 AAN09275   AF241237 AAF63331   AI534274   AI543547   AJ426851   AJ569406   AJ569407   AJ569408   AJ569409   AJ569410   AJ569411   AJ569412   AJ569414   AJ569415   AJ569416   AJ569417   AJ569418   AJ569419   AJ569420   AJ569421   AJ569422   AJ569423   AJ569425   AJ569426   AJ569427   AJ569428   AJ569429   AJ569430   AJ569431   AQ025352   AQ254772   AW941345   AW944480   AX154690   AY060967 AAL28515   AY069821 AAL39966   BE977342   BF489876   BF501371   BI164823   BI169440   BI173815   BI212268   BI214030   BI214244   BI232134   BI234694   BI361533   BI367336   BI483833   BI487061   BI569187   BI569188   BI578973   BI638664   BI641373   BP540412   BP540998   BP541000   BP546202   BP553621   BP553622   BP557609   BP557610   BP559738   BP559739   BT001739 AAN71494   CK00322   CO152662   CO155151   CO177242   CO264794   CO279808   CO286424   CO286447   CO308953   CO321272   CO324121   CO338342   CZ471596   CZ472474   CZ472695   CZ472696   CZ474115   CZ474753   CZ476107   CZ476112   CZ476309   CZ482294   CZ482305   CZ482306   CZ488707   CZ490556   CZ490557   DQ327759   EC056664   EC070021   EC073182   EC083878   EC086154   EC196779   EC196780   EC198358   EC200736   EC249649   EC261718   EC262891   EC263119   EC265193   EC268003   EG974120   ES690006
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IGK4 Q8IR99 Q95S41 Q9VZ69
Maps to
Does NOT map to
Identified with	CK00322 SD10340 (Nielsen et al., 2000) GM09708 RE72930 (BDGP Project Members, 2000-) SD07045 (BDGP Project Members, 2000-, Nielsen et al., 2000)
Mapped Features & Mutations
Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here Type Symbol & Location Additional Notes References
External Data
Linkouts	DEDB - Drosophila exon database: splicing graphs • 2449
Crossreferences
Expression Data
FlyBase-Curated Data
Transcript and Protein data	Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
Summary of Transcript Expression
Stage Tissue/Position Reference
Marker for
Subcellular Localization
CV Term
Summary of Polypeptide Expression
Stage Tissue/Position Reference
Marker for
Subcellular Localization
CV Term
Microarray Data
	Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002) AI534274
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030235 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • FBgn0030235 GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies • FBgn0030235
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable ImpCB04573 lethal | recessive ImpG0072 lethal | adult stage ImpG0072 lethal | pharate adult stage ImpG0072 Other Phenotypes Allele neuroanatomy defective | larval stage, with Scer\GAL4elav-C155 ImpEP1433 Phenotype manifest in Allele macrochaeta ImpBG01822 anterior fascicle & synapse, with Scer\GAL4elav-C155 ImpEP1433
Classical Alleles ( 27 )
For All Classical Alleles Show
Allele of Imp Class Mutagen Stocks Known lesion Imp2 P-element activity 0 Yes Imp7 P-element activity 0 Yes Imp8 P-element activity 0 Yes ImpBG01822 P-element activity 0 Yes ImpCB04573 P-element activity 0 Yes ImpEP1330 P-element activity 1 -- ImpEP1433 P-element activity 1 Yes ImpEP760 P-element activity 2 -- ImpG00080 P-element activity 0 -- ImpG00152 P-element activity 0 Yes ImpG0072 P-element activity 1 -- ImpG0293X 0 Yes ImpHC133 0 -- ImpYB0057 Δ2-3 0 -- ImpYD0166 piggyBac transposase 0 Yes Impd00435 P-element activity 1 -- Impd01837 P-element activity 1 -- Impd02239 P-element activity 1 -- Impd04757 P-element activity 1 -- Impd05843 P-element activity 0 -- Impd08180 P-element activity 0 -- Impd08187 P-element activity 0 -- Impd08578 P-element activity 1 -- Impe04542 piggyBac transposase 1 --