A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\AP-1γ

General Information
SymbolDmel\AP-1γSpeciesD. melanogaster
NameAP-1γAnnotation symbolCG9113
Feature typeprotein_coding_geneFlyBase IDFBgn0030089
Created / Updated2003-12-01/2007-03-20
Genomic Location
Chromosome (arm)XRecombination map
Cytogenetic map8C9-8C9Sequence locationX:9,002,726..9,011,773 [+]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
This gene is referred to in FlyBase by the symbol AP-1γ (CG9113, FBgn0030089). It has the cytological map location 8C9. Its sequence location is X:9002726..9011773. Its molecular function is described as: protein transporter activity; protein binding. It is involved in the biological processes: neurotransmitter secretion; synaptic vesicle coating; vesicle coating; intracellular protein transport; vesicle-mediated transport. 2 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides.

hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
8C9-8C9  
Limits computationally determined from genome sequence between P{EP}CG10962EP1565&P{EP}EP1030 and P{EP}EP1450&P{EP}EP1356  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Please see the GBrowse view of Dmel\AP-1γ for information on other features
detailed view FBtr0071293 FBtr0071294 FBtr0071296 FBtr0112965 FBtr0071298 FBtr0071295 FBtr0071297 FBpp0071229 FBpp0071232 FBpp0071230 FBpp0071231 FBpp0111878 FBpp0071233 FBpp0089134 FBti0058899 FBti0041832 FBti0069102
Comments on Gene Model
EST data suggest additional 3' exon(s)
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
AP-1gamma-RA
FBtr0071295
 NM_132299
  4692
  963
AP-1gamma-RB
FBtr0071294
 NM_167178
  4647
  976
AP-1gamma-RC
FBtr0071297
 NM_176717
  4710
  969
AP-1gamma-RD
FBtr0071296
 NM_176718
  4665
  982
AP-1gamma-RE
FBtr0071298
 NM_206671
  4630
  963
AP-1gamma-RF
FBtr0112965
 NM_001103448
  4970
  963
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
AP-1gamma-PA  
FBpp0071231  
104.5  
963  
5.55  
  NP_572527
  AAF46446
AP-1gamma-PB  
FBpp0071230  
106.3  
976  
5.47  
  NP_727311
  AAN09243
AP-1gamma-PC  
FBpp0071233  
105.1  
969  
5.46  
  NP_788890
  AAO41643
AP-1gamma-PD  
FBpp0071232  
106.9  
982  
5.39  
  NP_788891
  AAO41644
AP-1gamma-PE  
FBpp0089134  
104.5  
963  
5.55  
  NP_996394
  AAS65301
AP-1gamma-PF  
FBpp0111878  
104.5  
963  
5.55  
  NP_001096918
  ABW09366
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
•
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
Clathrin/coatomer adaptor, adaptin-like, N-terminal (IPR002553)
Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain (IPR008152)
Clathrin adaptor, gamma-adaptin, appendage (IPR008153)
Armadillo-like helical (IPR011989)
Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain (IPR013041)
Armadillo-type fold (IPR016024)
Adaptor protein complex AP-1, gamma subunit (IPR017107)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AA263940
 
AA567227
 
AE003446
AAF46446
 
AE003446
AAN09243
 
AE003446
AAO41643
 
AE003446
AAO41644
 
AE003446
AAS65301
 
AI106778
 
AI455103
 
BG633535
 
BG638255
 
BI163071
 
BI212596
 
BI215090
 
BI228291
 
BI352363
 
BI364094
 
BI364106
 
BI367619
 
BI369857
 
BI605915
 
BI607421
 
BI607500
 
BI608611
 
BI608876
 
BI609953
 
BI628273
 
BI630420
 
BT023757
 
CK661061
 
CK662018
 
CO152808
 
CO179327
 
CO179912
 
CO180401
 
CO186463
 
CO189407
 
CO190864
 
CO262426
 
CO264330
 
CO270695
 
CO277735
 
CO284162
 
CO290571
 
CO293513
 
CO293549
 
CO296565
 
CO299033
 
CO305079
 
CO310540
 
CO311652
 
CO315479
 
CO328761
 
CO332750
 
CO332802
 
CO340280
 
CZ482298
 
EC054246
 
EC058401
 
EC069322
 
EC070143
 
EC077533
 
EC078007
 
EC087550
 
EC087973
 
EC089279
 
EC090328
 
EC090660
 
EC196573
 
EC197367
 
EC198581
 
EC202310
 
EC203290
 
EC206947
 
EC207833
 
EC208740
 
EC209758
 
EC217346
 
EC224257
 
EC224267
 
EC228246
 
EC235717
 
EC236229
 
EC250634
 
EC259173
 
GM01375
 
LD21172
 
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    (BDGP Project Members, 2000-)
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Phenotype manifest in
        Allele
        hide Classical Alleles ( 1 )
        For All Classical Alleles Show

        Allele of AP-1γClassMutagenStocksKnown lesion
        AP-1γe045462 --
        hide Alleles Carried on Transgenic Constructs ( 1 )
        For All Alleles Carried on Transgenic Constructs Show

        Allele of AP-1γClassMutagenStocksKnown lesion
        AP-1γGD17111 Yes
        hide Aneuploid Aberrations
        Useful deficiency
         
        Useful duplication
         
        hide Transgenic Constructs & Insertions
        Transgenic Constructs
        Type of construct
        Name
        Expression data
        Insertions
        Type of insertions
        Name
        Expression data
        miscellaneous insertions
        PBac{RB}AP-1gammae04546
        NA
        insertion of mobile activating element
        P{EP}EP1500
        NA
        hide Related Comments
        Please look at the allele reports for the complete phenotype data
        hide Gene Ontology: Function, Process & Cellular Component ( 11 )
        hide Molecular Function
        CV term
        Evidence
        References
        protein binding
        inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR008152, InterPro:IPR008153, InterPro:IPR013041, InterPro:IPR017107
        (FlyBase Curators et al., 2004-)
        protein transporter activity
        inferred from electronic annotation with InterPro:IPR017107
        (FlyBase Curators et al., 2004-)
        hide Biological Process
        CV term
        Evidence
        References
        intracellular protein transport
        inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR008152, InterPro:IPR008153, InterPro:IPR013041
        (FlyBase Curators et al., 2004-)
        neurotransmitter secretion
        non-traceable author statement
        (Stimson and Ramaswami, 1999)
        synaptic vesicle coating
        traceable author statement
        (Stimson and Ramaswami, 1999)
        vesicle coating
        traceable author statement
        (Stimson and Ramaswami, 1999)
        vesicle-mediated transport
        inferred from electronic annotation with InterPro:IPR002553, InterPro:IPR008152, InterPro:IPR008153, InterPro:IPR013041
        (FlyBase Curators et al., 2004-)
        hide Cellular Component
        CV term
        Evidence
        References
        Golgi apparatus
        inferred from electronic annotation with InterPro:IPR017107
        (FlyBase Curators et al., 2004-)
        clathrin adaptor complex
        inferred from electronic annotation with InterPro:IPR008152, InterPro:IPR008153
        (FlyBase Curators et al., 2004-)
        coated vesicle
        traceable author statement
        (Stimson and Ramaswami, 1999)
        synaptic vesicle
        traceable author statement
        (Stimson and Ramaswami, 1999)
        hide Sequence Ontology: Class of Gene
        protein_coding_gene
         
        nuclear_gene
         
        hide Interactions & Pathways
        hide Summary of Genetic Interactions
        Interacts with
        Please look at the allele data for full details of the genetic interactions
        AP-1γ allele
        Gene
        References
        hide External Data
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        hide Orthologs
        Genome-wide drosophilid orthologs
        Curated drosophilid orthologs
         
        Linkouts
        InParanoid orthologs - Eukaryotic orthologs
        •
        hide Functional Complementation between Species
        hide Inter-Species Misexpression Data
        Produces phenotype in
        Produces NO phenotype in
        hide Stocks & Reagents
        hide Stocks Listed in FlyBase ( 5 )
        Szeged
        -
        P{EP}EP1500
        Bloomington
        17228
        w1118 P{EP}EP1500
        18271
        w1118 PBac{RB}AP-1gammae04546/FM7c
        Harvard
        -
        PBac{RB}AP-1gammae04546
        VDRC
        v3275
        w1118; P{GD1711}v3275/TM3
        hide Genomic Clones ( 2 )
        hide cDNA Clones ( 49 )
        Please Note
        This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
        cDNA Clones, Fully Sequenced
        BDGP DGC clones
        Other clones
        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        hide RNAi & Array Information
        Affy Oligo
        Linkouts
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        hide Antibody Information
        hide Other Information
        hide Discoverer
        hide Etymology
        hide Identification
        hide Position Effect Variegation Data
        hide Relationship to Other Genes
        Source for database identity of
        Source for identity of: AP-1γ CG9113
        (Verstreken and Bellen, 2000.9.4)
        Source for database merge of
        Additional comments
        hide Comments About Role
        hide Comments About Molecular Function
        hide Other Comments
        dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
        (Kiger et al., 2003)
        hide External Crossreferences & Linkouts
        Sequence Crossreferences
        RefSeq (Transcripts)
        •