Gene Dmel\CG31012

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General Information

Symbol

Dmel\CG31012

Species

D. melanogaster

Name

CG31012

Annotation symbol

CG31012

Feature type

protein_coding_gene

FlyBase ID

FBgn0027598

Created / Updated

2003-12-01/2003-12-01

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

100A6-100A6

Sequence location

3R:26,634,349..26,652,542 [+]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol CG31012 (FBgn0027598). It has the cytological map location 100A6. Its sequence location is 3R:26634349..26652542. Its molecular function is described as SH3/SH2 adaptor activity. The biological processes in which it is involved are not known. 10 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

100A6-100A6

Limits computationally determined from genome sequence between P{lacW}l(3)s2500^s2500 and P{PZ}Aph-4⁰⁷⁰²⁸&P{PZ}dco^rK215

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\CG31012 for information on other features

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG31012-RA

FBtr0085707

NM_170527

1886

545

CG31012-RB

FBtr0085706

NM_143570

2309

537

CG31012-RC

FBtr0085704

NM_170526

3800

882

CG31012-RD

FBtr0085705

NM_170528

2801

635

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG31012-PA

FBpp0085069

57.3

545

10.48

NP_733406

AAF57088

CG31012-PB

FBpp0085068

56.1

537

10.32

NP_651827

AAF57089

CG31012-PC

FBpp0085066

92.4

882

9.60

NP_733405

AAF57087

CG31012-PD

FBpp0085067

67.1

635

9.99

NP_733407

AAN14260

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

PANTHER - Protein classification by function, families, and pathways

•

FBgn0027598

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Neutrophil cytosol factor 2 (IPR000108)

Src homology-3 (IPR001452)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Maps to

Does NOT map to

Identified with

(BDGP Project Members, 2000-)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

DEDB - Drosophila exon database: splicing graphs

•

11404

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Microarray Data

Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002)

Untitled Document detailed view

AI542410
AI063388
AI292730

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0027598

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0027598

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

Phenotype manifest in

Allele

Classical Alleles ( 9 )

For All Classical Alleles Show

Allele of CG31012	Mutagen	Stocks	Known lesion
CG31012^CA06686	P-element activity	0	Yes
CG31012^CA06810	P-element activity	0	Yes
CG31012^EP3700	P-element activity	1	--
CG31012^EY02524	P-element activity	1	--
CG31012^KG05741	P-element activity	1	--
CG31012^c01086	piggyBac transposase	1	--
CG31012^c02040	piggyBac transposase	0	--
CG31012^f01073	piggyBac transposase	1	--
CG31012^f05244	piggyBac transposase	1	--

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG31012	Class	Mutagen	Stocks	Known lesion
CG31012^GD8679		in vitro construct \| RNAi in vitro construct \| regulatory fusion	1	Yes

Aneuploid Aberrations

Useful deficiency

Df(3R)tll-e

Useful duplication

Dp(3;3)516

Disrupted in

Df(3R)Exel8194

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD8679}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

PBac{PB}CG31012^c01086

PBac{PB}CG31012^c02040

PBac{WH}CG31012^f01073

PBac{WH}CG31012^f05244

P{PTT-GA}CG31012^CA06686

P{PTT-GA}CG31012^CA06810

P{SUPor-P}CG31012^KG05741

insertion of mobile activating element

P{EPgy2}CG31012^EY02524

P{EP}CG31012^EP3700

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 1 )

Molecular Function

CV term

Evidence

References

SH3/SH2 adaptor activity

inferred from sequence or structural similarity with EMBL:AF077003

(FlyBase, 1992-)

Biological Process

CV term

Evidence

References

Cellular Component

CV term

Evidence

References

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG31012 allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

68504

Drosophila PIMRider - The Drosophila Protein Interaction map

•

521609

Orthologs

Genome-wide drosophilid orthologs

Dana\GF22925

Dere\GG11778

Dgri\GH14216

Dpse\GA26879

Dsim\GD21548

Dvir\GJ24244

Dwil\GK14156

Dyak\GE10904

Curated drosophilid orthologs

Dmad\CG31012

(Munte, 2004.9.23)

Dpse\GA15936

Dsub\CG31012

(Munte, 2004.9.23)

Linkouts

InParanoid orthologs - Eukaryotic orthologs

•

ENSANGP00000012848
Anopheles gambiae (Ensembl)
ENSCAFP00000011855
Canis familiaris (Ensembl)
NEWSINFRUP00000143559
Takifugu rubripes (Ensembl)
ENSP00000302913
Homo sapiens (Ensembl)
ENSMMUP00000019194
Macaca mulatta (Ensembl)
ENSMODP00000010617
Monodelphis domestica (Ensembl)
ENSPTRP00000037241
Pan troglodytes (Ensembl)
ENSRNOP00000015803
Rattus norvegicus (Ensembl)
ENSXETP00000013641
Xenopus tropicalis (Ensembl)
WBGene00035339
Caenorhabditis briggsae (Wormbase)
WBGene00021549
Caenorhabditis elegans (Wormbase)
ZDB-GENE-041212-3
Danio rerio (Zfin)
MGI:1330281
Mus musculus (Informatics)

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 7 )

Szeged

P{EP}CG31012^EP3700

Harvard

PBac{PB}CG31012^c01086

PBac{WH}CG31012^f01073

PBac{WH}CG31012^f05244

VDRC

v38854

w¹¹¹⁸; P{GD8679}v38854

Bloomington

15869

y¹ w^67c23; P{EPgy2}CG31012^EY02524

14211

y¹ w^67c23; ry⁵⁰⁶ P{SUPor-P}CG31012^KG05741

Genomic Clones ( 1 )

BACR48I02

cDNA Clones ( 45 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones