Gene Dmel\CG16833

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General Information

Symbol

Dmel\CG16833

Species

D. melanogaster

Name

CG16833

Annotation symbol

CG16833

Feature type

protein_coding_gene

FlyBase ID

FBgn0026147

Created / Updated

2003-12-01/2003-12-01

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

32C1-32C1

Sequence location

2L:10,989,305..10,995,024 [+]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol CG16833 (FBgn0026147). It has the cytological map location 32C1. Its sequence location is 2L:10989305..10995024. Its molecular function is described as tubulin-tyrosine ligase activity. It is involved in the biological process protein modification process. 3 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

32C1-32C1

Limits computationally determined from genome sequence between P{lacW}l(2)k05812^k05812&P{lacW}l(2)k09104^k09104 and P{EP}ppo^EP2478&P{lacW}l(2)k15817^k15817

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Overall orientation not stated: piwi- CG12253+ CG16833+

(Cox et al., 1998)

Gene Model & Products

Please see the GBrowse view of Dmel\CG16833 for information on other features

Comments on Gene Model

DGC clone appears problematic: incomplete CDS (GH09663)

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG16833-RA

FBtr0080151

NM_143798

3973

827

CG16833-RB

FBtr0080150

NM_164953

4747

1070

CG16833-RC

FBtr0080152

NM_164954

4687

1070

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG16833-PA

FBpp0079740

95.2

827

9.74

NP_652055

AAF53045

CG16833-PB

FBpp0079739

123.0

1070

9.71

NP_723642

AAN10770

CG16833-PC

FBpp0079741

123.0

1070

9.71

NP_723643

AAN10771

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

PANTHER - Protein classification by function, families, and pathways

•

FBgn0026147

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Tubulin-tyrosine ligase (IPR004344)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Maps to

Does NOT map to

Identified with

bs33h01

(Oliver, 2001.8.16)

(BDGP Project Members, 2000-)

LD13681

(Cox et al., 1998, BDGP Project Members, 2000-)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

DEDB - Drosophila exon database: splicing graphs

•

7266

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Microarray Data

Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002)

Untitled Document detailed view

AI543850
AI110165

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0026147

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0026147

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 2 )

For All Classical Alleles Show

Allele of CG16833	Class	Mutagen	Stocks	Known lesion
CG16833^EY23195		P-element activity	1	--
CG16833^e01119		piggyBac transposase	2	--

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG16833	Class	Mutagen	Stocks	Known lesion
CG16833^GD9214		in vitro construct \| RNAi in vitro construct \| regulatory fusion	2	Yes

Aneuploid Aberrations

Useful duplication

Dp(2;2)Mdh3

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD9214}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

PBac{RB}CG16833^e01119

insertion of mobile activating element

P{EPgy2}CG16833^EY23195

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 2 )

Molecular Function

CV term

Evidence

References

tubulin-tyrosine ligase activity

inferred from sequence or structural similarity with UniProtKB:P38160

(FlyBase, 1992-)

Biological Process

CV term

Evidence

References

protein modification process

inferred from electronic annotation with InterPro:IPR004344

(FlyBase Curators et al., 2004-)

Cellular Component

CV term

Evidence

References

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG16833 allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

70901

Orthologs

Genome-wide drosophilid orthologs

Dere\GG23690

Dgri\GH10972

Dmoj\GI18156

Dper\GL19014

Dsim\GD23748

Dvir\GJ14582

Dwil\GK15248

Dyak\GE18502

Curated drosophilid orthologs

Dpse\GA14171

Linkouts

InParanoid orthologs - Eukaryotic orthologs

•

ENSANGP00000021502
Anopheles gambiae (Ensembl)
ENSCAFP00000022006
Canis familiaris (Ensembl)
NEWSINFRUP00000128674
Takifugu rubripes (Ensembl)
ENSGALP00000018519
Gallus gallus (Ensembl)
ENSP00000258398
Homo sapiens (Ensembl)
ENSMMUP00000008889
Macaca mulatta (Ensembl)
ENSMODP00000019197
Monodelphis domestica (Ensembl)
ENSRNOP00000023067
Rattus norvegicus (Ensembl)
GSTENP00029112001
Tetraodon nigroviridis (Ensembl)
WBGene00031388
Caenorhabditis briggsae (Wormbase)
WBGene00014232
Caenorhabditis elegans (Wormbase)
MGI:1914784
Mus musculus (Informatics)

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 5 )

VDRC

v32741

w¹¹¹⁸ P{GD9214}v32741

v32742

w¹¹¹⁸; P{GD9214}v32742

Harvard

PBac{RB}CG16833^e01119

Bloomington

17925

w¹¹¹⁸; PBac{RB}CG16833^e01119/CyO

22659

y¹ w^67c23; P{EPgy2}CG16833^EY23195

Genomic Clones ( 2 )

cDNA Clones ( 68 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones