A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\β'Cop

General Information
SymbolDmel\β'CopSpeciesD. melanogaster
Nameβ'-coatomer proteinAnnotation symbolCG6699
Feature typeprotein_coding_geneFlyBase IDFBgn0025724
Created / Updated2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)2LRecombination map
Cytogenetic map34B9-34B9Sequence location2L:13,378,897..13,382,391 [+]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
The gene β'-coatomer protein is referred to in FlyBase by the symbol β'Cop (CG6699, FBgn0025724). It has the cytological map location 34B9. Its sequence location is 2L:13378897..13382391. Its molecular function is described as: protein binding; structural molecule activity. It is involved in the biological processes: ER to Golgi vesicle-mediated transport; Golgi vesicle budding; retrograde vesicle-mediated transport, Golgi to ER; intracellular protein transport; vesicle-mediated transport. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
34B9-34B9  
Limits computationally determined from genome sequence between P{lacW}l(2)k00302k00302 and P{PZ}kuz03782&P{lacW}kuzk14817  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
34B5-34B9
(determined by in situ hybridisation)  
(Merdes, 1998.12.20)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Please see the GBrowse view of Dmel\β'Cop for information on other features
detailed view FBtr0080470 FBtr0080469 FBtr0080498 FBtr0100220 FBtr0080497 FBpp0080049 FBpp0080048 FBpp0080076 FBpp0099590 FBpp0080075 FBti0075839 FBti0006934 FBti0039280 FBti0069892 FBti0041938
Comments on Gene Model
DGC clone GH16479 appears problematic: incomplete CDS
DGC clone SD17630 appears problematic: incomplete CDS
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
β'Cop-RA
FBtr0080469
 NM_080097
  3080
  914
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
β'Cop-PA  
FBpp0080048  
102.7  
914  
4.90  
  NP_524836
  AAF53294
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
•
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
WD40/YVTN repeat-like (IPR015943)
WD40 repeat (IPR001680)
Coatomer, WD associated region (IPR006692)
WD40 repeat-like (IPR011046)
Coatomer, beta' subunit (IPR016453)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AA264134
 
AA438274
 
AA438276
 
AA438326
 
AA567350
 
AA698258
 
AA698893
 
AA736162
 
AA802426
 
AA802427
 
AA802967
 
AE003639
AAF53294
 
AI063563
 
AI135761
 
AI135771
 
AI258512
 
AI260519
 
AI293311
 
AI387691
 
AI389321
 
AI456603
 
AI530788
 
AI530929
 
AI530982
 
AI531353
 
AI531513
 
AI531850
 
AI532424
 
AI532509
 
AI532698
 
AI533064
 
AI533345
 
AI533525
 
AI533539
 
AI534522
 
AI534531
 
AI534931
 
AI542027
 
AI542782
 
AI542888
 
AI543089
 
AI544382
 
AI546460
 
AJ006523
CAA07084
 
AJ006524
CAA07085
 
AW940627
 
AY119527
AAM50181
 
BF506426
 
BG640482
 
BI164536
 
BI166397
 
BI168279
 
BI212929
 
BI213259
 
BI215441
 
BI228590
 
BI228642
 
BI230064
 
BI230103
 
BI232475
 
BI238921
 
BI355173
 
BI365720
 
BI373650
 
BI374548
 
BI375835
 
BI482366
 
BI484582
 
BI485774
 
BI578049
 
BI578643
 
BI616451
 
BI623334
 
BI632314
 
BI635260
 
BI635517
 
BI635916
 
BI636707
 
BI637860
 
BI638343
 
BI639732
 
BI639799
 
BI640828
 
BT023906
 
CK659547
 
CK660417
 
CO264886
 
CO265461
 
CO295740
 
CO297227
 
CO302431
 
CO303329
 
CO306170
 
CO335959
 
CO337123
 
CO338084
 
EC062035
 
EC084265
 
EC088552
 
EC198734
 
EC198996
 
EC213210
 
EC234533
 
EC237395
 
EC241537
 
EC261380
 
EC261518
 
EC267987
 
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    (BDGP Project Members, 2000-)
    (Dunne et al., 2002)
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide Microarray Data
        Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002)
        Untitled Document detailed view FBtr0080470 FBtr0080469 FBtr0080498 FBtr0100220 FBtr0080497
        AI293311
        AI063563
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Phenotype manifest in
        Allele
        hide Classical Alleles ( 0 )
        For All Classical Alleles Show

        Allele of β'CopClassMutagenStocksKnown lesion
        hide Alleles Carried on Transgenic Constructs ( 1 )
        For All Alleles Carried on Transgenic Constructs Show

        Allele of β'CopClassMutagenStocksKnown lesion
        β'CopGD120071 Yes
        hide Aneuploid Aberrations
        Useful duplication
         
        hide Transgenic Constructs & Insertions
        Transgenic Constructs
        Type of construct
        Name
        Expression data
        Insertions
        Type of insertions
        Name
        Expression data
        insertion of mobile activating element
        P{XP}d08097
        NA
        hide Related Comments
        Please look at the allele reports for the complete phenotype data
        hide Gene Ontology: Function, Process & Cellular Component ( 9 )
        hide Molecular Function
        CV term
        Evidence
        References
        protein binding
        inferred from electronic annotation with InterPro:IPR006692
        (FlyBase Curators et al., 2004-)
        structural molecule activity
        inferred from electronic annotation with InterPro:IPR006692
        (FlyBase Curators et al., 2004-)
        hide Biological Process
        CV term
        Evidence
        References
        ER to Golgi vesicle-mediated transport
        non-traceable author statement
        (Merdes, 1998.6.2)
        Golgi vesicle budding
        non-traceable author statement
        (Merdes, 1998.6.2)
        intracellular protein transport
        inferred from electronic annotation with InterPro:IPR006692
        (FlyBase Curators et al., 2004-)
        retrograde vesicle-mediated transport, Golgi to ER
        non-traceable author statement
        (Merdes, 1998.6.2)
        non-traceable author statement
        (Merdes, 1998.6.2)
        non-traceable author statement
        (Swiss-Prot Project Members, 2000.10.1)
        vesicle-mediated transport
        inferred from electronic annotation with InterPro:IPR006692
        (FlyBase Curators et al., 2004-)
        hide Cellular Component
        CV term
        Evidence
        References
        COPI vesicle coat
        non-traceable author statement
        (Merdes, 1998.6.2)
        non-traceable author statement
        (Merdes, 1998.6.2)
        non-traceable author statement
        (Swiss-Prot Project Members, 2000.10.1)
        membrane coat
        inferred from electronic annotation with InterPro:IPR006692
        (FlyBase Curators et al., 2004-)
        hide Sequence Ontology: Class of Gene
        protein_coding_gene
         
        nuclear_gene
         
        hide Interactions & Pathways
        hide Summary of Genetic Interactions
        Interacts with
        Please look at the allele data for full details of the genetic interactions
        β'Cop allele
        Gene
        References
        hide External Data
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        hide Orthologs
        Genome-wide drosophilid orthologs
        Curated drosophilid orthologs
         
        Linkouts
        InParanoid orthologs - Eukaryotic orthologs
        •
        hide Functional Complementation between Species
        hide Inter-Species Misexpression Data
        Produces phenotype in
        Produces NO phenotype in
        hide Stocks & Reagents
        hide Stocks Listed in FlyBase ( 1 )
        VDRC
        v42071
        w1118; P{GD12007}v42071
        hide Genomic Clones ( 2 )
        hide cDNA Clones ( 90 )
        Please Note
        This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
        cDNA Clones, Fully Sequenced
        BDGP DGC clones
        Other clones
        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        hide RNAi & Array Information
        Affy Oligo
        Linkouts
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        hide Antibody Information
        hide Other Information
        hide Discoverer
        hide Etymology
        hide Identification
        hide Position Effect Variegation Data
        hide Relationship to Other Genes
        Source for database identity of
        Source for identity of: β'Cop CG6699
        (Guan, 1999.11)
        Source for database merge of
        Additional comments
        hide Comments About Role
        hide Comments About Molecular Function