Gene Dmel\CG13369

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General Information

Symbol

Dmel\CG13369

Species

D. melanogaster

Name

CG13369

Annotation symbol

CG13369

Feature type

protein_coding_gene

FlyBase ID

FBgn0025640

Created / Updated

2003-12-01/2003-12-01

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

1B12-1B12

Sequence location

X:517,497..518,798 [+]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol CG13369 (FBgn0025640). It has the cytological map location 1B12. Its sequence location is X:517497..518798. Its molecular function is described as ribokinase activity. It is involved in the biological process D-ribose metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

1B12-1B12

Limits computationally determined from genome sequence between P{EP}svr^EP356&P{EP}arg^EP452 and P{EP}Dredd^EP1412&P{EP}Suv4-20^EP1216a

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\CG13369 for information on other features

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG13369-RA

FBtr0070115

NM_130494

1179

304

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG13369-PA

FBpp0070110

31.6

304

5.98

NP_569850

AAF45527

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

PANTHER - Protein classification by function, families, and pathways

•

FBgn0025640

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Ribokinase (IPR002139)

Carbohydrate/puine kinase, PfkB, conserved site (IPR002173)

Carbohydrate/purine kinase (IPR011611)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

O77425

Maps to

Does NOT map to

Identified with

LP11157

(Benos et al., 2001)

RH09469

(BDGP Project Members, 2000-)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

DEDB - Drosophila exon database: splicing graphs

•

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0025640

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0025640

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

CG13369^d06819

Sterility

Allele

fertile

CG13369^d06819

Phenotype manifest in

Allele

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of CG13369	Class	Mutagen	Stocks	Known lesion
CG13369^d06819		P-element activity	2	--

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG13369	Class	Mutagen	Stocks	Known lesion
CG13369^GD8000		in vitro construct \| RNAi in vitro construct \| regulatory fusion	2	Yes

Aneuploid Aberrations

Useful deficiency

Df(1)su(s)83

Useful duplication

Dp(1;2)E1

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD8000}

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{XP}CG13369^d06819

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 2 )

Molecular Function

CV term

Evidence

References

ribokinase activity

inferred from sequence or structural similarity

(EDGP Project Members, 1994-)

inferred from sequence or structural similarity with SGD_LOCUS:RBK1; SGD:S0000632

(FlyBase, 1992-)

Biological Process

CV term

Evidence

References

D-ribose metabolic process

inferred from electronic annotation with InterPro:IPR002139

(FlyBase Curators et al., 2004-)

Cellular Component

CV term

Evidence

References

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG13369 allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

57576

Orthologs

Genome-wide drosophilid orthologs

Dana\GF22103

Dere\GG12798

Dgri\GH12089

Dmoj\GI11097

Dper\GL21383

Dpse\GA12236

Dsec\GM19077

Dsim\GD16516

Dvir\GJ15781

Dwil\GK25613

Dyak\GE16624

Curated drosophilid orthologs

Dpse\GA12236

Linkouts

InParanoid orthologs - Eukaryotic orthologs

•

ENSANGP00000010594
Anopheles gambiae (Ensembl)
ENSCAFP00000007761
Canis familiaris (Ensembl)
ENSCINP00000012547
Ciona intestinalis (Ensembl)
NEWSINFRUP00000173799
Takifugu rubripes (Ensembl)
ENSGALP00000016302
Gallus gallus (Ensembl)
ENSP00000306817
Homo sapiens (Ensembl)
ENSMMUP00000018984
Macaca mulatta (Ensembl)
ENSMODP00000019446
Monodelphis domestica (Ensembl)
ENSPTRP00000020233
Pan troglodytes (Ensembl)
ENSRNOP00000006452
Rattus norvegicus (Ensembl)
GSTENP00034745001
Tetraodon nigroviridis (Ensembl)
ENSXETP00000014188
Xenopus tropicalis (Ensembl)
Q5SN59
Oryza sativa (Gramene)
AT1G17160.1
Arabidopsis thaliana (Arabidopsis)
WBGene00025817
Caenorhabditis briggsae (Wormbase)
WBGene00008548
Caenorhabditis elegans (Wormbase)
ZDB-CDNA-040625-167
Danio rerio (Zfin)
ZDB-GENE-040625-112
Danio rerio (Zfin)
MGI:1918586
Mus musculus (Informatics)
YCR036W
Saccharomyces cerevisiae (Yeastgenome)
NP_418208.1
Escherichia coliK12 (NCBI)
SPBC16G5.02c
Schizosaccharomyces pombe (Sanger)

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 4 )

Harvard

P{XP}CG13369^d06819

VDRC

v17158

w¹¹¹⁸; P{GD8000}v17158/CyO

v17161

w¹¹¹⁸; P{GD8000}v17161/TM3

Bloomington

19252

P{XP}CG13369^d06819 w¹¹¹⁸

Genomic Clones ( 1 )

BACR16G06

cDNA Clones ( 16 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

RH09469

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Affy Oligo

Linkouts

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0025640

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0025640

Antibody Information

Other Information

Discoverer

Etymology

Identification

Position Effect Variegation Data

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Comments About Role

Comments About Molecular Function

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_130494

RefSeq (Proteins)

•

NP_569850

DDBJ / EMBL / GenBank

•

UniProtKB/TrEMBL

•

O77425

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Ribokinase (IPR002139)

Carbohydrate/puine kinase, PfkB, conserved site (IPR002173)

Carbohydrate/purine kinase (IPR011611)

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

57576

DEDB - Drosophila exon database: splicing graphs

•

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0025640

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0025640

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0025640

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0025640

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0025640

InParanoid orthologs - Eukaryotic orthologs

•

ENSANGP00000010594
Anopheles gambiae (Ensembl)
ENSCAFP00000007761
Canis familiaris (Ensembl)
ENSCINP00000012547
Ciona intestinalis (Ensembl)
NEWSINFRUP00000173799
Takifugu rubripes (Ensembl)
ENSGALP00000016302
Gallus gallus (Ensembl)
ENSP00000306817
Homo sapiens (Ensembl)
ENSMMUP00000018984
Macaca mulatta (Ensembl)
ENSMODP00000019446
Monodelphis domestica (Ensembl)
ENSPTRP00000020233
Pan troglodytes (Ensembl)
ENSRNOP00000006452
Rattus norvegicus (Ensembl)
GSTENP00034745001
Tetraodon nigroviridis (Ensembl)
ENSXETP00000014188
Xenopus tropicalis (Ensembl)
Q5SN59
Oryza sativa (Gramene)
AT1G17160.1
Arabidopsis thaliana (Arabidopsis)
WBGene00025817
Caenorhabditis briggsae (Wormbase)
WBGene00008548
Caenorhabditis elegans (Wormbase)
ZDB-CDNA-040625-167
Danio rerio (Zfin)
ZDB-GENE-040625-112
Danio rerio (Zfin)
MGI:1918586
Mus musculus (Informatics)
YCR036W
Saccharomyces cerevisiae (Yeastgenome)
NP_418208.1
Escherichia coliK12 (NCBI)
SPBC16G5.02c
Schizosaccharomyces pombe (Sanger)

PANTHER - Protein classification by function, families, and pathways

•

FBgn0025640

Synonyms & Secondary IDs ( 2 )

Reported As

Symbol Synonym

CG13369

EG:115C2.1

(Benos et al., 2001, Giot et al., 2003, )

Name Synonym

CG13369

Secondary FlyBase IDs

References ( 10 )

Research paper

Benos et al., 2001, Genome Res. 11(5): 710--730: From First Base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies. [FBrf0135823]

Supplementary material

Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]

Personal communication to FlyBase

Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase.: Exelixis insertion alleles that are not in FlyBase. [FBrf0179797]
FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
Benos, 2000.12.13, FlyBase error report on Wed Dec 13 14:35:56 2000.: FlyBase error report on Wed Dec 13 14:35:56 2000. [FBrf0133222]

FlyBase analysis

FlyBase, 1992-, FlyBase curation: FlyBase curation. [FBrf0105495]

Computer file

BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.: Berkeley Drosophila Genome Project. [FBrf0125078]
EDGP Project Members, 1994-, European Drosophila Genome Mapping Project.: European Drosophila Genome Mapping Project. [FBrf0071734]

Automatic genome annotation

FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126705]