Gene Dmel\Dup99B

Help

Close All Open All

General Information

Symbol

Dmel\Dup99B

Species

D. melanogaster

Name

Ductus ejaculatorius peptide 99B

Annotation symbol

CG33495

Feature type

protein_coding_gene

FlyBase ID

FBgn0250832

Created / Updated

2008-02-21/2008-02-21

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

99B8-99B8

Sequence location

3R:25,540,725..25,541,153 [-]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

The gene Ductus ejaculatorius peptide 99B is referred to in FlyBase by the symbol Dup99B (CG33495, FBgn0250832). It has the cytological map location 99B8. Its sequence location is 3R:25540725..25541153. Its molecular function is described as hormone activity. It is involved in the biological processes: negative regulation of female receptivity, post-mating; oviposition; regulation of oviposition; negative regulation of female receptivity. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

99B8-99B8

Limits computationally determined from genome sequence between P{PZ}l(3)06743⁰⁶⁷⁴³ and P{PZ}ncd⁰⁵⁸⁸⁴ 99B8

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

99B-99B

(determined by in situ hybridisation)

(Saudan et al., 2002)

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\Dup99B for information on other features

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

Dup99B-RA

FBtr0089608

NM_206582

376

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

Dup99B-PA

FBpp0088975

6.2

10.05

NP_996305

AAS65225

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Sex peptide (IPR012608)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

P81160

UniProtKB/TrEMBL

Maps to

Does NOT map to

Identified with

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

External Data & Images

Linkouts

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 2 )

For All Classical Alleles Show

Allele of Dup99B	Class	Mutagen	Stocks	Known lesion
Dup99B^DG07301			1	--
Dup99B^TM6B			0	Yes

Alleles Carried on Transgenic Constructs ( 0 )

For All Alleles Carried on Transgenic Constructs Show

Allele of Dup99B	Class	Mutagen	Stocks	Known lesion

Aneuploid Aberrations

Useful deficiency

Df(3R)01215

Useful duplication

Dp(3;3)501

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

reporter construct

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

P{wHy}Dup99B^DG07301

Related Comments

Please look at the allele reports for the complete phenotype data

Dup99B peptide injected into the hemolymph of sexually mature, virgin females elicits postmating responses (increased oviposition and reduced receptivity).

(Saudan et al., 2002)

Gene Ontology: Function, Process & Cellular Component ( 6 )

Molecular Function

CV term

Evidence

References

hormone activity

inferred from electronic annotation with InterPro:IPR012608

(FlyBase Curators et al., 2004-)

Biological Process

CV term

Evidence

References

negative regulation of female receptivity

traceable author statement

(Kubli, 2003)

negative regulation of female receptivity, post-mating

inferred from mutant phenotype

(Saudan et al., 2002)

non-traceable author statement

(Billeter et al., 2002)

oviposition

inferred from mutant phenotype

(Saudan et al., 2002)

regulation of oviposition

non-traceable author statement

(Billeter et al., 2002)

traceable author statement

(Kubli, 2003)

Cellular Component

CV term

Evidence

References

extracellular region

non-traceable author statement

(Swiss-Prot Project Members, 1998.2.1)

inferred from electronic annotation with InterPro:IPR012608

(FlyBase Curators et al., 2004-)

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

Dup99B allele

Gene

References

External Data

Linkouts

Orthologs

Genome-wide drosophilid orthologs

Dsec\GM12229

Dsim\GD17687

Curated drosophilid orthologs

Linkouts

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 1 )

Bloomington

17431

y¹ w^67c23; P{wHy}Dup99B^DG07301

Genomic Clones ( 2 )

cDNA Clones ( 5 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

Nfly-013

RNAi & Array Information

Affy Oligo

Linkouts

Antibody Information

Other Information

Discoverer

Etymology

Identification

Position Effect Variegation Data

Relationship to Other Genes

Source for database identity of

Source for database merge of

Source for merge of: Dup99B anon-SAGE:Wang-013

(FlyBase, 1996-)

Additional comments

Comments About Role

Encodes a male peptide involved in mating elicited reduction of sexual receptivity increase of oviposition.

(Kubli et al., 1998)

Comments About Molecular Function

Other Comments

New annotation (CG33495) in release 3.2 of the genome annotation.

(FlyBase Genome Annotators, 2004)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_206582

RefSeq (Proteins)

•

NP_996305

DDBJ / EMBL / GenBank

•

UniProtKB/Swiss-Prot

•

P81160

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Sex peptide (IPR012608)

Linkouts

Synonyms & Secondary IDs ( 6 )

Reported As

Symbol Synonym

anon-SAGE:Wang-013

CG33495

DUP

(Gage, 2005, Peng et al., 2005)

DUP99B

(Yapici et al., 2008, Amrein, 2004, Peng et al., 2003, Peng et al., 2003, Liu et al., 2003, Peng et al., 2001, Rexhepaj et al., 2001, Nakayama and Aigaki, 2001, Rexhepaj et al., 2001)

Dup99B

Name Synonym

anon-SAGE:Wang-013

Ductus ejaculatorius peptide 99B

(Saudan et al., 2002, )

Secondary FlyBase IDs

FBgn0024381
FBgn0053495
FBgn0066985

References ( 39 )

Generate a list of

All references relating to this gene ( 39 )

List References by type

Recent research papers ( 1 )

Yapici et al., 2008, Nature 451(7174): 33--37: A receptor that mediates the post-mating switch in Drosophila reproductive behaviour. [FBrf0202765]

Show all research papers ...

Recent reviews (0)

All reviews listed in FlyBase were published before 2006

Show reviews ...