HomeGene Dmel\JIL-1
| General Information | |||
|---|---|---|---|
| Symbol | Dmel\JIL-1 | Species | D. melanogaster |
| Name | JIL-1 | Annotation symbol | CG6297 |
| Feature type | protein_coding_gene | FlyBase ID | FBgn0020412 |
| Created / Updated | 2003-12-01/2003-12-01 | ||
| Genomic Location | |||
| Chromosome (arm) | 3L | Recombination map | 3-31.4 |
| Cytogenetic map | 68A5-68A6 | Sequence location | 3L:11,071,849..11,086,239 [-] |
| Map ( GBrowse ) | 
| ||
Summary Information
| |||
|
Automatically generated summary
See sections below for more information | This gene is referred to in FlyBase by the symbol JIL-1 (CG6297, FBgn0020412). It has the cytological map location 68A5-68A6. Its sequence location is 3L:11071849..11086239. Its molecular function is described as: protein kinase activity; protein serine/threonine kinase activity; histone serine kinase activity (H3-S10 specific); ATP binding. It is involved in the biological processes: establishment and/or maintenance of chromatin architecture; protein amino acid phosphorylation; histone phosphorylation; negative regulation of chromatin silencing; female meiosis chromosome segregation; oogenesis; chromosome organization and biogenesis. 41 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; anatomical structure; intracellular organelle part; intracellular non-membrane-bounded organelle; intracellular organelle; chromatin; adult segment; adult; spindle; nucleus; egg; nervous system; abdominal sternite 5. It has 2 annotated transcripts and 2 annotated polypeptides. | ||
| External Summaries | |||
|
Detailed Mapping Data
| |||
| FlyBase Computed Cytological Location | |||
Cytogenetic map Evidence for location 68A5-68A6
Limits computationally determined from genome sequence between P{PZ}l(3)0123901239&P{lacW}l(3)01239j9B4 and P{PZ}CycA02461&P{PZ}CycA03946
| |||
| Experimentally Determined Cytological Location | |||
Cytogenetic map Notes References 68A-68A (determined by in situ hybridisation)
68A4-68A5 68A4-68A5 Localised by deficiency mapping, chromosomes unspecified.
| |||
| Experimentally Determined Recombination Data | |||
| Location | 3-31.4 3-31.4 +/- 0.8 3- | ||
| Left of (cM) | |||
| Right of (cM) | |||
| Notes | |||
| Molecular Map Data | |||
Gene Order (in direction of increasing cytology)
References Gene Order (overall orientation not stated) References | |||
|
Gene Model & Products
| |||
Please see the
GBrowse view of
Dmel\JIL-1
for information on other features
| |||
| Comments on Gene Model | |||
DGC clone appears problematic (LD01190): incomplete CDS. | |||
|
Transcript Data
| |||
| Annotated Transcripts | |||
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) | |||
| Additional Transcript Data & Comments | |||
| Reported size (kB) | |||
| Comments | |||
| External Data | |||
| Crossreferences | |||
|
Polypeptide Data
| |||
| Annotated Polypeptides | |||
Name FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
| |||
| Additional Polypeptide Data & Comments | |||
| Reported size (kD) | |||
| Comments | |||
| External Data | |||
| Linkouts | PANTHER
- Protein classification by function, families, and pathways
| ||
| Crossreferences | InterPro
domains - A database of protein families, domains, and functional sites
• Protein kinase, core (IPR000719)
Protein kinase, C-terminal (IPR000961)
Serine/threonine protein kinase (IPR002290)
Serine/threonine protein kinase, active site (IPR008271)
Protein kinase-like (IPR011009)
Protein kinase ATP binding, conserved site (IPR017441)
Serine/threonine protein kinase-related (IPR017442)
| ||
|
Sequences Consistent with the Gene Model
| |||
| DDBJ
/
EMBL / GenBank | DNA sequence Protein sequence Name | ||
| UniProtKB/Swiss-Prot | |||
| UniProtKB/TrEMBL | |||
| Maps to | |||
| Does NOT map to | |||
| Identified with | |||
|
Mapped Features & Mutations
| |||
Please see
GBrowse
or insertion reports for information on insertions of transgenic
constructs and features not listed here
Type Symbol & Location Additional Notes References point mutation JIL-1[3] 3L:11,074,223..11,074,223 comment=Position of mutation on reference sequence inferred by FlyBase curator based on author statement. Mutation truncates C terminal by 166 amino acids. evidence=experimental na_change=C11074223T pr_change=Q1042|JIL-1-PB,Q1042|JIL-1-PA reported_pr_change=??@ | |||
|
External Data
| |||
| Linkouts | DEDB
- Drosophila exon database: splicing graphs
• | ||
| Crossreferences | |||
|
Expression Data
| |||
| FlyBase-Curated Data | |||
|
Transcript and Protein data | Please see the FlyBase Gene Expression Report for details of gene expression from the literature. | ||
|
Summary of Transcript Expression
| |||
Stage Tissue/Position
Reference
| |||
| Marker for | |||
| Subcellular Localization | |||
| CV Term | |||
|
Summary of Polypeptide Expression
| |||
Stage Tissue/Position
Reference
| |||
| Marker for | |||
| Subcellular Localization | |||
| CV Term | |||
|
Microarray Data
|
|||
|
Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002) 
| |||
|
External Data & Images
| |||
| Linkouts | FLIGHT
- Cell culture data for RNAi and other high-throughput technologies
GEO (NCBI)
- Gene expression data: microarray and other high-throughput technologies
| ||
|
Alleles & Phenotypes
| |||
|
Summary of Allele Phenotypes
| |||
Lethality Allele semi-lethal (with JIL-1z60) semi-lethal (with JIL-1z2) Other Phenotypes Allele Sterility Allele female sterile (with JIL-1h9) female sterile (with JIL-1z2) Phenotype manifest in Allele egg chamber (with JIL-1z2) nurse cell (with JIL-1z2) oocyte nucleus (with JIL-1z2) egg chamber (with JIL-1h9) nurse cell (with JIL-1h9) oocyte nucleus (with JIL-1h9) | |||
