Gene Dmel\Ank2

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General Information

Symbol

Dmel\Ank2

Species

D. melanogaster

Name

Ank2

Annotation symbol

CG34416

Feature type

protein_coding_gene

FlyBase ID

FBgn0085445

Created / Updated

2006-05-09/2007-06-18

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

66A8-66A10

Sequence location

3L:7,648,480..7,711,439 [-]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Ank2 (CG34416, FBgn0085445). It has the cytological map location 66A8-66A10. Its sequence location is 3L:7648480..7711439. Its molecular function is described as: structural constituent of cytoskeleton; cytoskeletal protein binding; protein binding. It is involved in the biological processes: cytoskeletal anchoring; axon extension; signal transduction. 9 alleles are reported. No phenotypic data is available. It has 10 annotated transcripts and 10 annotated polypeptides.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

66A8-66A10

Limits computationally determined from genome sequence between P{PZ}l(3)07217⁰⁸²²³&P{EP}Rac2^EP3118 and P{lacW}Nmt^j1C7

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

66A-66A

(Hortsch, 1999.9.28)

66A8-66A9

(Serano, 2000.2.28)

66A-66A

(determined by in situ hybridisation)

(EDGP Project Members, 1994-)

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\Ank2 for information on other features

Comments on Gene Model

DGC clone GH01626 appears problematic: incomplete CDS

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

Ank2-RE

FBtr0112697

NM_001104064

2722

697

Ank2-RF

FBtr0112698

NM_001104065

13802

4114

Ank2-RG

FBtr0112699

NM_001104066

8895

2532

Ank2-RH

FBtr0112700

NM_001104067

6839

1716

Ank2-RI

FBtr0112693

NM_001043127

8841

2516

Ank2-RJ

FBtr0112701

NM_001104068

14027

4189

Ank2-RK

FBtr0112702

NM_001104069

14262

4264

Ank2-RL

FBtr0112694

NM_168227

13709

4083

Ank2-RM

FBtr0112695

NM_139891

7820

2404

Ank2-RN

FBtr0112696

NM_001104063

4757

1159

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

Ank2-PE

FBpp0111609

75.7

697

7.85

NP_001097534

ABW08484

Ank2-PF

FBpp0111610

452.5

4114

4.64

NP_001097535

ABW08485

Ank2-PG

FBpp0111611

279.2

2532

5.69

NP_001097536

ABW08486

Ank2-PH

FBpp0111612

188.0

1716

4.14

NP_001097537

AAG22324

Ank2-PI

FBpp0111605

275.2

2516

4.09

NP_001036592

ABI31241

Ank2-PJ

FBpp0111613

460.7

4189

4.61

NP_001097538

ABW08487

Ank2-PK

FBpp0111614

468.9

4264

4.83

NP_001097539

ABW08488

Ank2-PL

FBpp0111606

448.9

4083

4.65

NP_729285

AAF50525

Ank2-PM

FBpp0111607

264.8

2404

6.12

NP_648148

AAN12046

Ank2-PN

FBpp0111608

125.8

1159

7.33

NP_001097533

ABW08483

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

DEATH-like (IPR011029)

Ankyrin (IPR002110)

ZU5 (IPR000906)

Death (IPR000488)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Maps to

Does NOT map to

Identified with

GH01626

(BDGP Project Members, 2000-, Bouley et al., 2000)

GH14650

(BDGP Project Members, 2000-)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

External Data & Images

Linkouts

Alleles & Phenotypes

Summary of Allele Phenotypes

Other Phenotypes

Allele

neuroanatomy defective, with Scer\GAL4^IG1-1

Ank2^{dsRNA.Scer\UAS}

Phenotype manifest in

Allele

dorsal multidendritic neuron ddaE & axon, with Scer\GAL4^IG1-1

Ank2^{dsRNA.Scer\UAS}

Classical Alleles ( 5 )

For All Classical Alleles Show

Allele of Ank2	Mutagen	Stocks	Known lesion
Ank2^MB00005		1	--
Ank2^MB02773		1	--
Ank2^MB04517		1	--
Ank2^f00518	piggyBac transposase	1	--
Ank2^f02001		2	--

Alleles Carried on Transgenic Constructs ( 4 )

For All Alleles Carried on Transgenic Constructs Show

Allele of Ank2	Mutagen	Stocks	Known lesion
Ank2^GD10869	in vitro construct \| RNAi in vitro construct \| regulatory fusion	2	Yes
Ank2^GD12247	in vitro construct \| RNAi in vitro construct \| regulatory fusion	1	Yes
Ank2^GD9649	in vitro construct \| RNAi in vitro construct \| regulatory fusion	0	Yes
Ank2^{dsRNA.Scer\UAS}	in vitro construct \| regulatory fusion in vitro construct \| RNAi	0	Yes