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Gene Dmel\Acp29AB

General Information
Symbol	Dmel\Acp29AB	Species	D. melanogaster
Name	Accessory gland-specific peptide 29AB	Annotation symbol	CG17797
Feature type	protein_coding_gene	FlyBase ID	FBgn0015583
Created / Updated	2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	29C1-29C1	Sequence location	2L:8,392,466..8,393,239 [-]
Map ( GBrowse )	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Accessory gland-specific peptide 29AB is referred to in FlyBase by the symbol Acp29AB (CG17797, FBgn0015583). It has the cytological map location 29C1. Its sequence location is 2L:8392466..8393239. Its molecular function is described as: galactose binding; sugar binding; hormone activity; binding. It is involved in the biological processes: sperm displacement; sperm competition; post-mating behavior. 43 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 29C1-29C1   Limits computationally determined from genome sequence between P{lacW}l(2)k12914k12914&P{lacW}Akap200k07118a and P{lacW}l(2)k03706k03706&P{lacW}Acerk07704
Experimentally Determined Cytological Location
Cytogenetic map Notes References 29C1-29C5   (Celniker, 1998.3.17) 29A-29B   (Aguade, 1999.2.19) 29A-29B (determined by in situ hybridisation)   (Wolfner et al., 1997) 29B-29B (determined by in situ hybridisation)   (Clark et al., 1995)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology) References Gene Order (overall orientation not stated) References Overall orientation not stated: Peritrophin-15a+ Peritrophin-15b+ lectin-29Ca? Acp29AB? (Wijffels et al., 2001)
Gene Model & Products
Please see the GBrowse view of Dmel\Acp29AB for information on other features
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Acp29AB-RA FBtr0079716  NM_078788   774   234
Additional Transcript Data & Comments
Reported size (kB)	0.95 (northern blot) (Wolfner et al., 1997)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kD) Length (aa) Theoretical pI RefSeq ID GenBank protein Acp29AB-PA   FBpp0079321   27.2   234   7.96     NP_523512   AAF52665
Additional Polypeptide Data & Comments
Reported size (kD)	234 (aa) (Wolfner et al., 1997)
Comments
External Data
Linkouts	PANTHER - Protein classification by function, families, and pathways • FBgn0015583
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • C-type lectin (IPR001304) C-type lectin-like (IPR016186) C-type lectin fold (IPR016187)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AC004423   AE003621 AAF52665   AJ240513 CAB53187   AJ240514 CAB53188   AJ240515 CAB53189   AJ240516 CAB53190   AJ240517 CAB53191   AJ240518 CAB53192   AJ240519 CAB53193   AJ240520 CAB53194   AJ240521 CAB53195   AJ240522 CAB53196   AJ240523 CAB53197   AJ240524 CAB53198   AJ240525 CAB53199   AJ240526 CAB53200   AJ240527 CAB53201   AJ240528 CAB53202   AJ240529 CAB53203   AJ240530 CAB53204   AJ240531 CAB53205   AJ240532 CAB53206   AJ240533 CAB53207   AJ240534 CAB53208   AJ240535 CAB53209   AJ240536 CAB53210   AJ240537 CAB53211   AJ240538 CAB53212   AJ240539 CAB53213   AJ240540 CAB53214   AJ240541 CAB53215   AJ240542 CAB53216   AJ240543 CAB53217   AJ240544 CAB53218   AJ240545 CAB53219   AJ240546 CAB53220   AJ240547 CAB53221   AJ240548 CAB53222   AJ240549 CAB53223   AJ240550 CAB53224   AJ240551 CAB53225   AY010527 AAG32559   AY010528 AAG32560   AY010529 AAG32561   AY010530 AAG32562   AY010531 AAG32563   AY010532 AAG32564   AY010533 AAG32565   AY010534 AAG32566   AY010535 AAG32567   AY010536 AAG32568   AY010537 AAG32569   AY010538 AAG32570   AY010539 AAG32571   AY010540 AAG32572   AY010541 AAG32573   AY010542 AAG32574   AY010543 AAG32575   AY344305 AAR05024   AY344306 AAR05025   AY344307 AAR05026   AY344308 AAR05027   AY344309 AAR05028   AY344310 AAR05029   AY344311 AAR05030   AY344312 AAR05031   AY344313 AAR05032   AY344314 AAR05033   AY344315 AAR05034   AY344316 AAR05035   AY344317 AAR05036   AY344318 AAR05037   AY344319 AAR05038   AY344320 AAR05039   AY344321 AAR05040   AY344322 AAR05041   AY344323 AAR05042   AY344324 AAR05043   AY635210 AAT49116   AY635211 AAT49117   AY635212 AAT49118   AY635213 AAT49119   AY635214 AAT49120   AY635215 AAT49121   AY635216 AAT49122   AY635217 AAT49123   EL869984   EL869985   EL869986   EL869987   EL869988   EL869989   EL869990   EL869991   U85758 AAB96382
UniProtKB/Swiss-Prot	O46197
UniProtKB/TrEMBL
Maps to	DS02110 (Theopold et al., 1999, Celniker, 1998.3.17)
Does NOT map to
Identified with
Mapped Features & Mutations
Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here Type Symbol & Location Additional Notes References
External Data
Linkouts	DEDB - Drosophila exon database: splicing graphs • 6918
Crossreferences
Expression Data
FlyBase-Curated Data
Transcript and Protein data	Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
Summary of Transcript Expression
Stage Tissue/Position Reference  adult stage | male  male accessory gland main cell (Wolfner et al., 1997)  adult stage | male  male accessory gland (Wolfner et al., 1997)
Marker for
Subcellular Localization
CV Term
Summary of Polypeptide Expression
Stage Tissue/Position Reference
Marker for
Subcellular Localization
CV Term
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0015583 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • FBgn0015583 GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies • FBgn0015583
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4hs.PB Acp29ABScer\UAS.cLa viable, with Scer\GAL4αTub84B.PL Acp29ABScer\UAS.cLa Phenotype manifest in Allele
Classical Alleles ( 41 )
For All Classical Alleles Show
Allele of Acp29AB Class Mutagen Stocks Known lesion Acp29AB1 0 -- Acp29AB2 0 -- Acp29ABLa13 natural population 0 -- Acp29ABLa14 natural population 0 -- Acp29ABLa15 natural population 0 -- Acp29ABLa16 natural population 0 -- Acp29ABLa1 natural population 0 -- Acp29ABLa21 natural population 0 -- Acp29ABLa25 natural population 0 -- Acp29ABLa34 natural population 0 -- Acp29ABLa35 natural population 0 -- Acp29ABLa3 natural population 0 -- Acp29ABLa4 natural population 0 -- Acp29ABLa5 natural population 0 -- Acp29ABLa6 natural population 0 -- Acp29ABLa9 natural population 0 -- Acp29ABMa13 natural population 0 -- Acp29ABMa18 natural population 0 -- Acp29ABMa20 natural population 0 -- Acp29ABMa21 natural population 0 -- Acp29ABMa43 natural population 0 -- Acp29ABMa45 natural population 0 -- Acp29ABMa48 natural population 0 -- Acp29ABMa50 natural population 0 -- Acp29ABMa52 natural population 0 -- Acp29ABMa5 natural population 0 -- Acp29ABMa67 natural population 0 -- Acp29ABMa7 natural population 0 -- Acp29ABMa8 natural population 0 -- Acp29ABMo15b natural population 0 -- Acp29ABMo1b natural population 0 -- Acp29ABMo2b natural population 0 -- Acp29ABMo34a natural population 0 -- Acp29ABMo36a natural population 0 -- Acp29ABMo37a natural population 0 -- Acp29ABMo40b natural population 0 -- Acp29ABMo47a natural population 0 -- Acp29ABMo52b natural population 0 -- Acp29ABMo58b natural population 0 -- Acp29ABMo80b natural population 0 -- Acp29ABMo8b natural population 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Acp29AB Class Mutagen Stocks Known lesion Acp29ABGD5362 in vitro construct | RNAi in vitro construct | regulatory fusion 2 Yes Acp29ABScer\UAS.cLa in vitro construct | regulatory fusion 0 Yes
Aneuploid Aberrations
Useful deficiency	Df(2L)TE29Aa-16
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5362} NA P{UAS-Acp29AB.L} NA
Insertions
	Type of insertions Name Expression data
Related Comments
	Please look at the allele reports for the complete phenotype data
Gene Ontology: Function, Process & Cellular Component ( 8 )
Molecular Function
CV term Evidence References
binding inferred from electronic annotation with InterPro:IPR001304, InterPro:IPR016186, InterPro:IPR016187 (FlyBase Curators et al., 2004-)
galactose binding inferred from sequence or structural similarity (Theopold et al., 1999)
hormone activity non-traceable author statement (FlyBase, 1992-)
sugar binding inferred from sequence or structural similarity (Mueller et al., 2004)
Biological Process
CV term Evidence References
post-mating behavior non-traceable author statement (Swiss-Prot Project Members, 2000.10.1)
sperm competition traceable author statement (Chapman, 2001)
sperm displacement non-traceable author statement (FlyBase, 1992-) non-traceable author statement (Billeter et al., 2002)
Cellular Component
CV term Evidence References
extracellular region non-traceable author statement (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	protein_coding_gene   nuclear_gene
Interactions & Pathways
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Acp29AB allele Gene References
External Data
Linkouts	BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions • 60286
Orthologs
Genome-wide drosophilid orthologs	Dana\GF15345 Dsec\Acp29AB Dsim\Acp29AB
Curated drosophilid orthologs	Dmau\Acp29AB (Jones et al., 2003) Dsec\Acp29AB (Jones et al., 2003) Dsim\Acp29AB (Aguade, 1999) Dyak\Acp29AB (Jones et al., 2003)
Linkouts
Functional Complementation between Species
Inter-Species Misexpression Data
Produces phenotype in
Produces NO phenotype in
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )