A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\CG10349

General Information
SymbolDmel\CG10349SpeciesD. melanogaster
NameCG10349Annotation symbolCG10349
Feature typeprotein_coding_geneFlyBase IDFBgn0015350
Created / Updated2005-01-10/2005-01-10
Genomic Location
Chromosome (arm)3RRecombination map3-
Cytogenetic map89E3-89E3Sequence location3R:12,705,450..12,710,832 [+]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
This gene is referred to in FlyBase by the symbol CG10349 (FBgn0015350). It has the cytological map location 89E3. Its sequence location is 3R:12705450..12710832. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
89E3-89E3  
Limits computationally determined from genome sequence between P{lacW}CSN5L4032 and P{EP}MESK4EP1015  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
3-
 
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
In direction of increasing cytology: Fas1+ nonA-l+ Cctγ+ CG14906- CG31217- CG31217- Ubx- bxd- Glut3+ abd-A- iab-4+ CG10349+ Abd-B- Actn3- Ahcy89E-
(Martin et al., 1995)
Gene Order (overall orientation not stated)
References
Overall orientation not stated: abd-A- iab-4? CG10349? anon-89Ec? Abd-B-
(Casares and Sanchez-Herrero, 1995)
hide Gene Model & Products
Please see the GBrowse view of Dmel\CG10349 for information on other features
detailed view FBtr0083364 FBpp0082807
Comments on Gene Model
Gene model uncertain: Comparative genomics of Drosophila species show conservation patterns atypical for protein-coding regions, suggesting that this gene might not have protein function (FBrf0204466).
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
CG10349-RA
FBtr0083364
 NM_142319
  1298
  417
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
CG10349-PA  
FBpp0082807  
45.2  
417  
10.71  
  NP_650576
  AAF55361
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
•
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
EGF-like region, conserved site (IPR013032)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AE003715
AAF55361
 
AE003715
AAO41570
 
U31961
AAA84404
 
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Phenotype manifest in
        Allele
        hide Classical Alleles ( 0 )
        For All Classical Alleles Show

        Allele of CG10349ClassMutagenStocksKnown lesion
        hide Alleles Carried on Transgenic Constructs ( 1 )
        For All Alleles Carried on Transgenic Constructs Show

        Allele of CG10349ClassMutagenStocksKnown lesion
        CG10349GD69531 Yes
        hide Aneuploid Aberrations
        Useful deficiency
         
        Useful duplication
         
        hide Transgenic Constructs & Insertions
        Transgenic Constructs
        Type of construct
        Name
        Expression data
        UAS construct
        P{GD6953}
        NA
        Insertions
        Type of insertions
        Name
        Expression data
        hide Related Comments
        Please look at the allele reports for the complete phenotype data
        hide Gene Ontology: Function, Process & Cellular Component ( 3 )
        hide Molecular Function
        CV term
        Evidence
        References
        molecular_function
        no biological data available
        (FlyBase Curators, 2002-)
        hide Biological Process
        CV term
        Evidence
        References
        biological_process
        no biological data available
        (FlyBase Curators, 2002-)
        hide Cellular Component
        CV term
        Evidence
        References
        cellular_component
        no biological data available
        (FlyBase Curators, 2002-)
        hide Sequence Ontology: Class of Gene
        protein_coding_gene
         
        nuclear_gene
         
        hide Interactions & Pathways
        hide Summary of Genetic Interactions
        Interacts with
        Please look at the allele data for full details of the genetic interactions
        CG10349 allele
        Gene
        References
        hide External Data
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        hide Orthologs
        Genome-wide drosophilid orthologs
        Curated drosophilid orthologs
         
        Linkouts
        hide Functional Complementation between Species
        hide Inter-Species Misexpression Data
        Produces phenotype in
        Produces NO phenotype in
        hide Stocks & Reagents
        hide Stocks Listed in FlyBase ( 1 )
        VDRC
        v42924
        w1118; P{GD6953}v42924/CyO
        hide Genomic Clones ( 1 )
        hide cDNA Clones ( 0 )
        Please Note
        This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
        cDNA Clones, Fully Sequenced
        BDGP DGC clones
        Other clones
        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        hide RNAi & Array Information
        Affy Oligo
        Linkouts
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        hide Antibody Information
        hide Other Information
        hide Discoverer
        hide Etymology
        hide Identification
        hide Position Effect Variegation Data
        hide Relationship to Other Genes
        Source for database identity of
        Source for database merge of
        Additional comments
        hide Comments About Role
        hide Comments About Molecular Function
        hide Other Comments
        Located near the iab-5 and iab-6 cis-regulatory regions. The complete sequence of the bithorax complex is available.
        (Martin et al., 1995)
        hide External Crossreferences & Linkouts
        Sequence Crossreferences
        RefSeq (Transcripts)
        •
        RefSeq (Proteins)
        •
        DDBJ / EMBL / GenBank
        •
        UniProtKB/Swiss-Prot
        •
        Other Crossreferences
        InterPro domains - A database of protein families, domains, and functional sites
        •
        EGF-like region, conserved site (IPR013032)
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        DEDB - Drosophila exon database: splicing graphs
        •
        DRSC - RNAi screening (Harvard): high-throughput cell culture data and design
        •
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data
        •
        PANTHER - Protein classification by function, families, and pathways
        •
        hide Synonyms & Secondary IDs ( 7 )
        Reported As
        Symbol Synonym
        anon-89Ea
         
        CG10349
        (Lin and Kellis, 2006.12.15)
        CG-CG10349
        (Moshkin et al., 2001)
        CT29078
        (Hynes and Zhao, 2000)
        II
        (Casares and Sanchez-Herrero, 1995)
        Name Synonym
        candidate gene 5
        (Martin et al., 1995, )
        CG10349
         
        domain II
        (Sanchez-Herrero and Akam, 1989)
        Secondary FlyBase IDs
          hide References ( 10 )
          Research paper
          Moshkin et al., 2001, Proc. Natl. Acad. Sci. USA 98(2): 570--574
          The Bithorax complex of Drosophila melanogaster. Underreplication and morphology in polytene chromosomes. [FBrf0134831]
          Singh et al., 1997, Nucleic Acids Res. 25(7): 1419--1425
          Mathematical model to predict regions of chromatin attachment to the nuclear matrix. [FBrf0093731]
          Casares and Sanchez-Herrero, 1995, Development 121(6): 1855--1866
          Regulation of infraabdominal regions of the Bithorax complex of Drosophila by gap genes. [FBrf0078174]
          Martin et al., 1995, Proc. Natl. Acad. Sci. USA 92(18): 8398--8402
          Complete sequence of the bithorax complex of Drosophila. [FBrf0083285]
          Sanchez-Herrero and Akam, 1989, Development 107: 321--329
          Spatially ordered transcription of regulatory DNA in the Bithorax complex of Drosophila. [FBrf0049550]
          Supplementary material
          Hynes and Zhao, 2000, J. Cell Biol. 150(2):
          Table S6. EGF repeat and related adhesion proteins. [FBrf0132110]
          Personal communication to FlyBase
          Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center
          RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
          Lin and Kellis, 2006.12.15, Gene models flagged as uncertain or dubious.
          Gene models flagged as uncertain or dubious. [FBrf0204466]
          FlyBase analysis
          FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase.
          Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398]
          Protein sequence record
          Swiss-Prot Project Members, 1996.10.1, UniProtKB: P53404
          Hypothetical protein CG10349 in chromosome 3. [FBrf0156830]