Gene Dmel\Set

Help

Close All Open All

General Information

Symbol

Dmel\Set

Species

D. melanogaster

Name

Set

Annotation symbol

CG4299

Feature type

protein_coding_gene

FlyBase ID

FBgn0014879

Created / Updated

2003-12-01/2003-12-01

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

88E8-88E8

Sequence location

3R:11,089,257..11,090,975 [+]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Set (CG4299, FBgn0014879). It has the cytological map location 88E8. Its sequence location is 3R:11089257..11090975. Its molecular function is described as cyclin binding. It is involved in the biological process nucleosome assembly. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

88E8-88E8

Limits computationally determined from genome sequence between P{lacW}Hsc70-4^L3929 and P{lacW}MRG15^j6A3

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\Set for information on other features

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

Set-RA

FBtr0083062

NM_142181

1186

269

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

Set-PA

FBpp0082521

31.0

269

3.99

NP_650438

AAF55155

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

PANTHER - Protein classification by function, families, and pathways

•

FBgn0014879

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Nucleosome assembly protein (NAP) (IPR002164)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

P53997

UniProtKB/TrEMBL

Q540W9

Maps to

Does NOT map to

Identified with

LD23703

(BDGP Project Members, 2000-)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

DEDB - Drosophila exon database: splicing graphs

•

9536

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0014879

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

FBgn0014879

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0014879

BDGP expression data

•

Show all BDGP original images, annotations and embryonic microarray data for Set

FlyExpress - Embryonic expression images (BDGP data)

•

Show all FlyExpress processed images for Set

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

Set^EY09821

Sterility

Allele

fertile

Set^EY09821

Phenotype manifest in

Allele

Classical Alleles ( 2 )

For All Classical Alleles Show

Allele of Set	Class	Mutagen	Stocks	Known lesion
Set^EY09821		P-element activity	1	--
Set^f03083		piggyBac transposase	1	--

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of Set	Class	Mutagen	Stocks	Known lesion
Set^GD11279		in vitro construct \| RNAi in vitro construct \| regulatory fusion	1	Yes

Aneuploid Aberrations

Useful duplication

Dp(3;3)C123.3

Disrupted in

Df(3R)E(mod)4-1^P11

(Pai et al., 2004)

Df(3R)Exel7323

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD11279}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

PBac{WH}Set^f03083

insertion of mobile activating element

P{EPgy2}EY02255

P{EPgy2}Set^EY09821

Related Comments

Please look at the allele reports for the complete phenotype data

A Set cDNA has been cloned and sequenced.

(Kellogg et al., 1995)

Gene Ontology: Function, Process & Cellular Component ( 3 )

Molecular Function

CV term

Evidence

References

cyclin binding

non-traceable author statement

(Swiss-Prot Project Members, 1996.10.1)

Biological Process

CV term

Evidence

References

nucleosome assembly

inferred from electronic annotation with InterPro:IPR002164

(FlyBase Curators et al., 2004-)

Cellular Component

CV term

Evidence

References

nucleus

inferred from sequence or structural similarity with EMBL:AB015613; protein_id:BAA34736.1

(FlyBase, 1992-)

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

Set allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

66908

Orthologs

Genome-wide drosophilid orthologs

Dana\GF11410

Dere\GG16903

Dgri\GH18852

Dmoj\GI22922

Dper\GL12537

Dpse\GA18091

Dsec\GM24211

Dsim\GD19001

Dvir\GJ23206

Dwil\GK13791

Dyak\GE24285

Curated drosophilid orthologs

Dpse\GA18091

Linkouts

InParanoid orthologs - Eukaryotic orthologs

•

ENSANGP00000011355
Anopheles gambiae (Ensembl)
ENSBTAP00000027913
Bos taurus (Ensembl)
ENSCAFP00000026226
Canis familiaris (Ensembl)
ENSCINP00000000521
Ciona intestinalis (Ensembl)
NEWSINFRUP00000155617
Takifugu rubripes (Ensembl)
ENSGALP00000007476
Gallus gallus (Ensembl)
ENSP00000238274
Homo sapiens (Ensembl)
ENSMMUP00000011186
Macaca mulatta (Ensembl)
ENSMODP00000007870
Monodelphis domestica (Ensembl)
ENSPTRP00000036650
Pan troglodytes (Ensembl)
ENSRNOP00000039454
Rattus norvegicus (Ensembl)
GSTENP00030996001
Tetraodon nigroviridis (Ensembl)
Q69JW2
Oryza sativa (Gramene)
AT1G74560.2
Arabidopsis thaliana (Arabidopsis)
WBGene00040415
Caenorhabditis briggsae (Wormbase)
WBGene00005007
Caenorhabditis elegans (Wormbase)
ZDB-CDNA-040425-819
Danio rerio (Zfin)
ZDB-GENE-030131-433
Danio rerio (Zfin)
MGI:1860267
Mus musculus (Informatics)
MGI:3612444
Mus musculus (Informatics)
SPBC36B7.08c
Schizosaccharomyces pombe (Sanger)

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 4 )

Harvard

PBac{WH}Set^f03083

VDRC

v21827

w¹¹¹⁸; P{GD11279}v21827/TM3

Bloomington

15409

y¹ w^67c23; P{EPgy2}EY02255

16954

y¹ w^67c23; P{EPgy2}Set^EY09821

Genomic Clones ( 2 )

cDNA Clones ( 71 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones