Gene Dmel\ctp

General Information
Symbol	Dmel\ctp	Species	D. melanogaster
Name	cut up	Annotation symbol	CG6998
Feature type	protein_coding_gene	FlyBase ID	FBgn0011760
Created / Updated	2003-12-01/2006-05-09
Genomic Location
Chromosome (arm)	X	Recombination map	1-
Cytogenetic map	4C13-4C14	Sequence location	X:4,581,834..4,593,918 [+]
Map ( GBrowse )
Summary Information
Automatically generated summary See sections below for more information	The gene cut up is referred to in FlyBase by the symbol ctp (CG6998, FBgn0011760). It has the cytological map location 4C13-4C14. Its sequence location is X:4581834..4593918. Its molecular function is described as: ATPase activity, coupled; microtubule motor activity; protein binding; dynein intermediate chain binding; protein homodimerization activity. It is involved in the biological processes: microtubule-based movement; bristle morphogenesis; spermatogenesis; imaginal disc-derived wing morphogenesis; sperm individualization; spermatid nuclear elongation; actin filament bundle formation; microtubule-based process. 41 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; anatomical structure; nervous system; peripheral nervous system; adult segment; adult mesothoracic segment; nuclear part; embryonic nervous system; spermatocyte; spermatozoon; thoracic segment; adult; commissure. It has 4 annotated transcripts and 4 annotated polypeptides.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 4C13-4C14 Limits computationally determined from genome sequence between P{EP}CG2930^EP1352 and P{EP}EP425
Experimentally Determined Cytological Location
Cytogenetic map Notes References 4C15-4D2 (determined by in situ hybridisation) 4C5--8 (determined by in situ hybridisation) 4C7--8 (determined by in situ hybridisation) 4D1--2 (determined by in situ hybridisation) 4C13--16 (determined by in situ hybridisation) 4C11--14 (determined by in situ hybridisation) 4C15--CD3 (determined by in situ hybridisation) (Peter et al., 2002) 4C7-4C8 (determined by in situ hybridisation) (Schaefer et al., 1999.12.2) 4D-4D (Li, 1996.2.9) 4E1-4E2 (Dick, 1995.8.1) 4C15-4D3 (determined by in situ hybridisation) 4D1--2 (determined by in situ hybridisation) 4C5--8 (determined by in situ hybridisation) 4C15--D2 (determined by in situ hybridisation) 4D1--2 (determined by in situ hybridisation) (Schaefer et al., 1999.8.12) 4C11-4C14 (determined by in situ hybridisation) 4C13--16 (determined by in situ hybridisation) (Schaefer et al., 1999.6.15) 4D1-4D3 (determined by in situ hybridisation) (Phillis et al., 1996) 4E1-4E2 (determined by in situ hybridisation) (Dick et al., 1996) 4D-4D (determined by in situ hybridisation) (Gramates and Phillis, 1995)
Experimentally Determined Recombination Data
Location	1- (Dick, 1995.8.1)
Left of (cM)	ct (Phillis et al., 1994)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology) References Gene Order (overall orientation not stated) References Overall orientation not stated: ctp- Pp2C1+ (Dick et al., 1997)
Gene Model & Products
Please see the GBrowse view of Dmel\ctp for information on other features
Comments on Gene Model
	A longer orf, downstream of the one chosen, can be made from these gene models but BLAST evidence supports the one shown. GenBank record U48848 suggests additional 3prime exons
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) ctp-RA FBtr0070706 NM_080336 1472 89 ctp-RB FBtr0070704 NM_167014 1605 89 ctp-RC FBtr0070707 NM_167015 2205 89 ctp-RD FBtr0070705 NM_167016 1463 89
Additional Transcript Data & Comments
Reported size (kB)	4.5, 2.4 (northern blot) (Dick et al., 1996)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kD) Length (aa) Theoretical pI RefSeq ID GenBank protein ctp-PA FBpp0070674 10.4 89 7.50 NP_525075 AAF45975 ctp-PB FBpp0070672 10.4 89 7.50 NP_726942 AAN09126 ctp-PC FBpp0070675 10.4 89 7.50 NP_726943 AAN09127 ctp-PD FBpp0070673 10.4 89 7.50 NP_726944 AAN09128
Additional Polypeptide Data & Comments
Reported size (kD)	89 (aa); 10 (kD predicted) (Dick et al., 1996)
Comments
External Data
Linkouts	PANTHER - Protein classification by function, families, and pathways • FBgn0011760
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Dynein light chain, type 1 and 2 (IPR001372)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201563 AA263959 AA391327 AA392231 AA392261 AA440053 AA440510 AA735238 AA802175 AA820434 AA821093 AA948807 AA949175 AA978560 AA979427 AE003431 AAF45975 AE003431 AAN09126 AE003431 AAN09127 AE003431 AAN09128 AI109315 AI238641 AI257308 AI260785 AI260824 AI292550 AI293363 AI387858 AI389488 AI389839 AI403372 AI403469 AI405765 AI512087 AI512810 AI516163 AI518701 AI543711 AI945386 AI946354 AJ426676 AJ426678 AJ426679 AJ426683 AJ426684 AJ426685 AJ426686 AJ426687 AX777274 AY094798 AAM11151 BF489003 BG632235 BG632347 BG633413 BG633495 BG635226 BG639355 BG639371 BG641463 BH011447 BI161702 BI161703 BI163360 BI163895 BI164259 BI166013 BI166242 BI167026 BI167426 BI167539 BI170506 BI172772 BI173029 BI173107 BI173306 BI173490 BI173746 BI173964 BI212748 BI215891 BI215957 BI228825 BI229077 BI229178 BI231296 BI231887 BI232911 BI233048 BI234063 BI234143 BI235697 BI237956 BI240081 BI241270 BI241820 BI243122 BI352656 BI355418 BI355565 BI356162 BI356262 BI357115 BI357913 BI361957 BI362327 BI362478 BI364805 BI365177 BI366659 BI367215 BI367746 BI368509 BI368779 BI369070 BI370468 BI370959 BI371145 BI372125 BI372605 BI372827 BI373381 BI375001 BI375412 BI482425 BI482866 BI483012 BI564701 BI577601 BI578845 BI579126 BI579448 BI580511 BI580721 BI581882 BI593518 BI614140 BI620281 BI620445 BI635213 BI635893 BI640317 BP543994 BP546016 BP546486 BP548546 BP553563 BP557941 BP557942 CK445265 CK662020 CO154245 CO177267 CO195020 CO196146 CO266944 CO274747 CO275123 CO279720 CO280535 CO285065 CO285832 CO290882 CO295571 CO296536 CO307812 CO308121 CO308645 CO316680 CO320413 CO320898 CO321905 CO325131 CO330619 CO333017 CO335860 CZ474730 EC056970 EC057788 EC063008 EC067452 EC069297 EC069390 EC070426 EC072141 EC073090 EC079327 EC080783 EC083691 EC086949 EC088559 EC090045 EC194719 EC200374 EC201484 EC204782 EC205255 EC205590 EC207369 EC216285 EC219273 EC220981 EC222228 EC222471