A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\OstStt3

General Information
SymbolDmel\OstStt3SpeciesD. melanogaster
NameOligosaccharyl transferase 3Annotation symbolCG7748
Feature typeprotein_coding_geneFlyBase IDFBgn0011336
Created / Updated2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)3RRecombination map
Cytogenetic map96B19-96B20Sequence location3R:20,892,434..20,895,372 [-]
Map ( GBrowse ) detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
The gene Oligosaccharyl transferase 3 is referred to in FlyBase by the symbol OstStt3 (CG7748, FBgn0011336). It has the cytological map location 96B19-96B20. Its sequence location is 3R:20892434..20895372. Its molecular function is described as: oligosaccharyl transferase activity; phosphopantetheine binding. It is involved in the biological process protein amino acid glycosylation. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
96B19-96B20  
Limits computationally determined from genome sequence between P{PZ}ssh01207 and P{lacW}OstStt3j2D9  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
96B19-96B20
(determined by in situ hybridisation)  
(Spradling et al., 1999)
96B19-96B20
 
(BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Please see the GBrowse view of Dmel\OstStt3 for information on other features
detailed view FBtr0084787 FBtr0084788 FBtr0084765 FBtr0084786 FBtr0084766 FBtr0084767 FBtr0084768 FBtr0113284 FBpp0084163 FBpp0084162 FBpp0084140 FBpp0084161 FBpp0084141 FBti0058223 FBti0045175 FBti0048449 FBti0004931 FBti0050303 FBti0025591 FBti0042143 FBti0029395 FBti0029182
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
OstStt3-RA
FBtr0084786
 NM_079770
  2716
  774
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
OstStt3-PA  
FBpp0084161  
87.6  
774  
9.27  
  NP_524494
  AAF56391
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
•
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
Oligosaccharyl transferase, STT3 subunit (IPR003674)
Phosphopantetheine attachment site (IPR006162)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AA694951
 
AA949890
 
AE003750
AAF56391
 
AF132552
AAD27851
 
AI107144
 
AI133998
 
AI135629
 
AI257750
 
AI295381
 
AI297771
 
AI513252
 
AI514952
 
AI531138
 
AI532108
 
AI533035
 
AI533215
 
AI542327
 
AQ026308
 
AX799088
 
BF486090
 
BF489372
 
BF496296
 
BF502026
 
BF502679
 
BF503420
 
BF504378
 
BF506253
 
BG636414
 
BG640860
 
BG641064
 
BG641172
 
BI162865
 
BI163592
 
BI166509
 
BI167839
 
BI168455
 
BI170396
 
BI170481
 
BI171940
 
BI172808
 
BI173041
 
BI173583
 
BI227902
 
BI237763
 
BI242003
 
BI354111
 
BI357074
 
BI362994
 
BI363168
 
BI364613
 
BI364972
 
BI370013
 
BI373819
 
BI374189
 
BI374334
 
BI484774
 
BI579570
 
BI586931
 
BI632973
 
BI635692
 
BP550015
 
CK657451
 
CK657649
 
CK659033
 
CK659064
 
CK659968
 
CO182924
 
CO194814
 
CO270232
 
CO273325
 
CO278537
 
CO284658
 
CO295419
 
CO296113
 
CO319309
 
CO321157
 
CO330260
 
CO337666
 
CO341294
 
CO341542
 
CZ469647
 
CZ481465
 
DN154327
 
EC059386
 
EC064073
 
EC074032
 
EC076510
 
EC083968
 
EC195019
 
EC198666
 
EC201931
 
EC216272
 
EC220812
 
EC221600
 
EC224746
 
EC231374
 
EC235995
 
EC237049
 
EC238052
 
EC238884
 
EC240821
 
EC252202
 
EC255950
 
EC263407
 
EL871090
 
EL871091
 
EL871207
 
EL871208
 
EL871325
 
EL871326
 
EL871442
 
EL871443
 
EL876366
 
EL876367
 
GH13452
 
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    (Spradling et al., 1999, BDGP Project Members, 2000-)
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    DEDB - Drosophila exon database: splicing graphs
    •
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide Microarray Data
        Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002)
        Untitled Document detailed view FBtr0084787 FBtr0084788 FBtr0084765 FBtr0084786 FBtr0084766 FBtr0084767 FBtr0084768 FBtr0113284
        AI135629
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        FlyExpress - Embryonic expression images (BDGP data)
        •
        Show all FlyExpress processed images for OstStt3
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Lethality
        Allele
        lethal | recessive
        Phenotype manifest in
        Allele
        hide Classical Alleles ( 3 )
        For All Classical Alleles Show

        Allele of OstStt3ClassMutagenStocksKnown lesion
        OstStt3c049690 --
        OstStt3e037101 --
        OstStt3j2D91 --
        hide Alleles Carried on Transgenic Constructs ( 1 )
        For All Alleles Carried on Transgenic Constructs Show

        Allele of OstStt3ClassMutagenStocksKnown lesion
        OstStt3GD2610 Yes
        hide Aneuploid Aberrations
        Useful deficiency
         
        Useful duplication
         
        Disrupted in
        (Christensen et al., 2008.4.15)
        (Christensen et al., 2008.4.15)
        Not disrupted in
        (Spradling et al., 1999, BDGP Project Members, 1994-1999)
        hide Transgenic Constructs & Insertions
        Transgenic Constructs
        Type of construct
        Name
        Expression data
        UAS construct
        P{GD261}
        NA
        Insertions
        Type of insertions
        Name
        Expression data
        miscellaneous insertions
        PBac{PB}OstStt3c04969
        NA
        PBac{RB}OstStt3e03710
        NA
        insertion of enhancer trap
        P{lacW}OstStt3j2D9
        No
        hide Related Comments
        Please look at the allele reports for the complete phenotype data
        hide Gene Ontology: Function, Process & Cellular Component ( 4 )
        hide Molecular Function
        CV term
        Evidence
        References
        oligosaccharyl transferase activity
        inferred from sequence or structural similarity
        (Spradling et al., 1999)
        inferred from sequence or structural similarity with SGD_LOCUS:STT3; SGD:S0002990
        (FlyBase, 1992-)
        phosphopantetheine binding
        inferred from electronic annotation with InterPro:IPR006162
        (FlyBase Curators et al., 2004-)
        hide Biological Process
        CV term
        Evidence
        References
        protein amino acid glycosylation
        inferred from electronic annotation with InterPro:IPR003674
        (FlyBase Curators et al., 2004-)
        hide Cellular Component
        CV term
        Evidence
        References
        oligosaccharyl transferase complex
        inferred from sequence or structural similarity
        (Spradling et al., 1999)
        inferred from sequence or structural similarity with SGD_LOCUS:STT3; SGD:S0002990
        (FlyBase, 1992-)
        hide Sequence Ontology: Class of Gene
        protein_coding_gene
         
        nuclear_gene
         
        hide Interactions & Pathways
        hide Summary of Genetic Interactions
        Interacts with
        Please look at the allele data for full details of the genetic interactions
        OstStt3 allele
        Gene
        References
        hide External Data
        Linkouts
        BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
        •
        hide Orthologs
        Genome-wide drosophilid orthologs
        Curated drosophilid orthologs
        Linkouts
        InParanoid orthologs - Eukaryotic orthologs
        •
        hide Functional Complementation between Species
        hide Inter-Species Misexpression Data
        Produces phenotype in
        Produces NO phenotype in
        hide Stocks & Reagents
        hide Stocks Listed in FlyBase ( 2 )
        Harvard
        -
        PBac{RB}OstStt3e03710
        Bloomington
        10340
        y1 w1118; P{lacW}OstStt3j2D9/TM3, Sb1
        hide Genomic Clones ( 2 )
        hide cDNA Clones ( 80 )
        Please Note
        This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
        cDNA Clones, Fully Sequenced
        BDGP DGC clones
        Other clones
        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones