HomeGene Dmel\Rac1
| General Information | |||
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| Symbol | Dmel\Rac1 | Species | D. melanogaster |
| Name | Rac1 | Annotation symbol | CG2248 |
| Feature type | protein_coding_gene | FlyBase ID | FBgn0010333 |
| Created / Updated | 2003-12-01/2003-12-01 | ||
| Genomic Location | |||
| Chromosome (arm) | 3L | Recombination map | 3- |
| Cytogenetic map | 61F5-61F5 | Sequence location | 3L:1,300,879..1,302,683 [-] |
| Map ( GBrowse ) | 
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Summary Information
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Automatically generated summary
See sections below for more information | This gene is referred to in FlyBase by the symbol Rac1 (CG2248, FBgn0010333). It has the cytological map location 61F5. Its sequence location is 3L:1300879..1302683. Its molecular function is described as: GTPase activity; GTP binding. It is involved in the biological processes described with 43 unique terms, many of which group under: anatomical structure development; cell motility; ovarian follicle cell development; regulation of neurogenesis; regulation of developmental process; cell projection organization and biogenesis; transport; cell proliferation; actin filament-based process; organelle organization and biogenesis. 41 alleles are reported. The phenotypes of these alleles are annotated with 79 unique terms, many of which group under: organ system; nervous system; embryonic nervous system; peripheral nervous system; adult segment; embryonic neuron; embryonic/larval tracheal system; adult brain; adult mesothoracic segment; embryonic/larval hemocoel. It has one annotated transcript and one annotated polypeptide. | ||
| External Summaries | |||
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Detailed Mapping Data
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| FlyBase Computed Cytological Location | |||
Cytogenetic map Evidence for location 61F5-61F5
Limits computationally determined from genome sequence between P{PZ}l(3)0596705967 and P{PZ}l(3)0264002640
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| Experimentally Determined Cytological Location | |||
Cytogenetic map Notes References 61F-61F (determined by in situ hybridisation)
61F-61F (determined by in situ hybridisation)
61F5-61F5 | |||
| Experimentally Determined Recombination Data | |||
| Location | 3- | ||
| Left of (cM) | |||
| Right of (cM) | |||
| Notes | |||
| Molecular Map Data | |||
Gene Order (in direction of increasing cytology)
References Gene Order (overall orientation not stated) References | |||
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Gene Model & Products
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Please see the
GBrowse view of
Dmel\Rac1
for information on other features
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| Comments on Gene Model | |||
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Transcript Data
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| Annotated Transcripts | |||
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) | |||
| Additional Transcript Data & Comments | |||
| Reported size (kB) | 2.4 (northern blot) 2.0 (northern blot) 2.2 (northern blot) | ||
| Comments | |||
| External Data | |||
| Crossreferences | |||
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Polypeptide Data
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| Annotated Polypeptides | |||
Name FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
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| Additional Polypeptide Data & Comments | |||
| Reported size (kD) | |||
| Comments | |||
| External Data | |||
| Linkouts | PANTHER
- Protein classification by function, families, and pathways
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| Crossreferences | InterPro
domains - A database of protein families, domains, and functional sites
• Ras GTPase (IPR001806)
Ras small GTPase, Rho type (IPR003578)
Small GTP-binding protein (IPR005225)
Ras (IPR013753)
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Sequences Consistent with the Gene Model
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| DDBJ
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EMBL / GenBank | DNA sequence Protein sequence Name | ||
| UniProtKB/Swiss-Prot | |||
| UniProtKB/TrEMBL | |||
| Maps to | |||
| Does NOT map to | |||
| Identified with | |||
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Mapped Features & Mutations
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Please see
GBrowse
or insertion reports for information on insertions of transgenic
constructs and features not listed here
Type Symbol & Location Additional Notes References deletion Rac1[Df] 3L:1,232,627..1,302,283 point mutation Rac1[J10] 3L:1,302,246..1,302,246 comment=Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change. evidence=experimental na_change=C1285778T pr_change=P34L|Rac1-PA reported_pr_change=P?L point mutation Rac1[J11] 3L:1,302,168..1,302,168 comment=Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change. evidence=experimental na_change=G1285700A pr_change=G60E|Rac1-PA reported_pr_change=G?E point mutation Rac1[J6] 3L:1,302,150..1,302,150 comment=Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change. evidence=experimental na_change=G1285682A pr_change=R66Q|Rac1-PA reported_pr_change=R?Q | |||
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External Data
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| Linkouts | DEDB
- Drosophila exon database: splicing graphs
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| Crossreferences | |||
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Expression Data
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| FlyBase-Curated Data | |||
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Transcript and Protein data | Please see the FlyBase Gene Expression Report for details of gene expression from the literature. | ||
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Summary of Transcript Expression
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Stage Tissue/Position
Reference
embryonic stage
embryonic stage
embryonic stage | stage 10-12
somatic mesoderm
embryonic stage | blastoderm
embryonic stage
embryonic/larval digestive system
embryonic stage
embryonic central nervous system
embryonic stage-adult stage | |||
| Marker for | |||
| Subcellular Localization | |||
| CV Term | |||
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Summary of Polypeptide Expression
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Stage Tissue/Position
Reference
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| Marker for | |||
| Subcellular Localization | |||
| CV Term | |||
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External Data & Images
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| Linkouts | FLIGHT
- Cell culture data for RNAi and other high-throughput technologies
FlyAtlas
- Adult expression by tissue, using Affymetrix Dros2 array
GEO (NCBI)
- Gene expression data: microarray and other high-throughput technologies
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Alleles & Phenotypes
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Summary of Allele Phenotypes
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Lethality Allele Other Phenotypes Allele Phenotype manifest in Allele ventral adult lateral neuron & commissure axon & dorsal cluster neuron | somatic clone photoreceptor cell & axon, with Scer\GAL4GMR.PF microchaeta & wing, with Scer\GAL4ptc-559.1 indirect flight muscle & larva, with Scer\GAL41151 ventral nerve cord & embryo, with Scer\GAL4crq.PO | |||