Gene Dmel\snRNA:U1:95Cc

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General Information

Symbol

Dmel\snRNA:U1:95Cc

Species

D. melanogaster

Name

small nuclear RNA U1 at 95Cc

Annotation symbol

CR31185

Feature type

snRNA_gene

FlyBase ID

FBgn0004187

Created / Updated

2003-12-01/2003-12-01

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

95C1-95C1

Sequence location

3R:19,652,056..19,652,219 [+]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

The gene small nuclear RNA U1 at 95Cc is referred to in FlyBase by the symbol snRNA:U1:95Cc (CR31185, FBgn0004187). It has the cytological map location 95C1. Its sequence location is 3R:19652056..19652219. Its molecular function is unknown. It is involved in the biological process nuclear mRNA splicing via U2-type spliceosome. No alleles are reported. It has one annotated transcript.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

95C1-95C1

Limits computationally determined from genome sequence between P{PZ}l(3)04684⁰⁴⁶⁸⁴ and P{PZ}Atg6⁰⁰⁰⁹⁶

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

95C-95C

(determined by in situ hybridisation)

(Lo and Mount, 1990)

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

Gene Order (overall orientation not stated)

References

Overall orientation not stated: snRNA:U1:95Cc+ snRNA:U1:95Cb+ snRNA:U1:95Ca-

(Lo and Mount, 1990)

Gene Model & Products

Please see the GBrowse view of Dmel\snRNA:U1:95Cc for information on other features

Comments on Gene Model

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

snRNA:U1:95Cc-RA

FBtr0084487

NR_002076

164

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Name

M17639

X53544

Maps to

Does NOT map to

Identified with

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0004187

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of snRNA:U1:95Cc	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 0 )

For All Alleles Carried on Transgenic Constructs Show

Allele of snRNA:U1:95Cc	Class	Mutagen	Stocks	Known lesion

Aneuploid Aberrations

Useful deficiency

Df(3R)mbc-R.1

Useful duplication

Dp(3;3)M95A⁺13

Disrupted in

Df(3R)Exel9014

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{GSV1}C933.1^C933.1

Related Comments

Please look at the allele reports for the complete phenotype data

snRNA:U1:95Cc has been cloned and sequenced.

(Lo and Mount, 1990)

Gene Ontology: Function, Process & Cellular Component ( 2 )

Molecular Function

CV term

Evidence

References

Biological Process

CV term

Evidence

References

nuclear mRNA splicing via U2-type spliceosome

inferred from sequence or structural similarity

(Mount and Salz, 2000)

Cellular Component

CV term

Evidence

References

snRNP U1

inferred from sequence or structural similarity

(Mount and Salz, 2000)

Sequence Ontology: Class of Gene

snRNA_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

snRNA:U1:95Cc allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

534059

Orthologs

Genome-wide drosophilid orthologs

Curated drosophilid orthologs

Linkouts

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 0 )

Genomic Clones ( 1 )

BACR11E07

cDNA Clones ( 0 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Affy Oligo

Linkouts

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0004187

Other Information

Discoverer

Etymology

Identification

Position Effect Variegation Data

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Comments About Role

Comments About Molecular Function

Coordinates (on date of analysis) on AE003745:22328..22491.

(Mount, 2000.5)

Other Comments

New annotation (CR31185) in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NR_002076

DDBJ / EMBL / GenBank

•

Other Crossreferences

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

534059

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0004187

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0004187

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0004187

Synonyms & Secondary IDs ( 14 )

Reported As

Symbol Synonym

CR31185

(Molnar et al., 2006)

(Wooley et al., 1982)

snRNA:U1

snRNA:U1:95Cc

(Molnar et al., 2006)

snRNA-U1-95.3

(Dominski et al., 2003, Yuan et al., 2003, Harding et al., 2002, Price et al., 1998, Wang and Stumph, 1998, Wang et al., 1996, Deshpande et al., 1996, Matunis et al., 1993, Saluz et al., 1988, Myslinski et al., 1984, Li et al., 2004)

U1-95.3

(Jensen et al., 1998, Lo and Mount, 1990)

U1:95Cc

(Lai et al., 2005, Hernandez et al., 2007)

U1c-95Cc

(Mount and Salz, 2000)

U1 snRNA

(Labourier et al., 2001, Nagengast et al., 2001, Reim et al., 1999, Gonsalvez et al., 2006)

U1snRNA

(Horowitz and Krainer, 1994, Wang and Stumph, 1995, Duckett et al., 1995, )

U1snRNA95Cc

Name Synonym

small nuclear RNA U1

small nuclear RNA U1 at 95Cc

Secondary FlyBase IDs

FBgn0003915
FBgn0003918
FBgn0051185

References ( 30 )

Generate a list of

All references relating to this gene ( 30 )

List References by type

Recent research papers ( 3 )

Hernandez et al., 2007, Nucleic Acids Res. 35(1): 21--34: Insect small nuclear RNA gene promoters evolve rapidly yet retain conserved features involved in determining promoter activity and RNA polymerase specificity. [FBrf0194208]
Gonsalvez et al., 2006, Curr. Biol. 16(11): 1077--1089: The Sm-protein methyltransferase, dart5, is essential for germ-cell specification and maintenance. [FBrf0193526]
Molnar et al., 2006, Genetics 174(3): 1635--1659: A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. [FBrf0195387]

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Recent reviews (0)

All reviews listed in FlyBase were published before 2006

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